These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
262 related articles for article (PubMed ID: 19725510)
1. The pyrrolobenzodiazepine dimer SJG-136 forms sequence-dependent intrastrand DNA cross-links and monoalkylated adducts in addition to interstrand cross-links. Rahman KM; Thompson AS; James CH; Narayanaswamy M; Thurston DE J Am Chem Soc; 2009 Sep; 131(38):13756-66. PubMed ID: 19725510 [TBL] [Abstract][Full Text] [Related]
2. Sequence-selective interaction of the minor-groove interstrand cross-linking agent SJG-136 with naked and cellular DNA: footprinting and enzyme inhibition studies. Martin C; Ellis T; McGurk CJ; Jenkins TC; Hartley JA; Waring MJ; Thurston DE Biochemistry; 2005 Mar; 44(11):4135-47. PubMed ID: 15766241 [TBL] [Abstract][Full Text] [Related]
3. Nuclear magnetic resonance solution structures of inter- and intrastrand adducts of DNA cross-linker SJG-136. Hopton SR; Thompson AS Biochemistry; 2011 May; 50(21):4720-32. PubMed ID: 21488658 [TBL] [Abstract][Full Text] [Related]
4. Sequence-selective recognition of duplex DNA through covalent interstrand cross-linking: kinetic and molecular modeling studies with pyrrolobenzodiazepine dimers. Smellie M; Bose DS; Thompson AS; Jenkins TC; Hartley JA; Thurston DE Biochemistry; 2003 Jul; 42(27):8232-9. PubMed ID: 12846572 [TBL] [Abstract][Full Text] [Related]
5. Competitive reactions of interstrand and intrastrand DNA-Pt adducts: A dinuclear-platinum complex preferentially forms a 1,4-interstrand cross-link rather than a 1,2 intrastrand cross-link on binding to a GG 14-mer duplex. Berners-Price SJ; Davies MS; Cox JW; Thomas DS; Farrell N Chemistry; 2003 Feb; 9(3):713-25. PubMed ID: 12569464 [TBL] [Abstract][Full Text] [Related]
6. SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 1: cellular pharmacology, in vitro and initial in vivo antitumor activity. Hartley JA; Spanswick VJ; Brooks N; Clingen PH; McHugh PJ; Hochhauser D; Pedley RB; Kelland LR; Alley MC; Schultz R; Hollingshead MG; Schweikart KM; Tomaszewski JE; Sausville EA; Gregson SJ; Howard PW; Thurston DE Cancer Res; 2004 Sep; 64(18):6693-9. PubMed ID: 15374986 [TBL] [Abstract][Full Text] [Related]
7. An assay combining high-performance liquid chromatography and mass spectrometry to measure DNA interstrand cross-linking efficiency in oligonucleotides of varying sequences. Narayanaswamy M; Griffiths WJ; Howard PW; Thurston DE Anal Biochem; 2008 Mar; 374(1):173-81. PubMed ID: 18082123 [TBL] [Abstract][Full Text] [Related]
8. Highly efficient sequence-specific DNA interstrand cross-linking by pyrrole/imidazole CPI conjugates. Bando T; Narita A; Saito I; Sugiyama H J Am Chem Soc; 2003 Mar; 125(12):3471-85. PubMed ID: 12643709 [TBL] [Abstract][Full Text] [Related]
9. Effect of base sequence on the DNA cross-linking properties of pyrrolobenzodiazepine (PBD) dimers. Rahman KM; James CH; Thurston DE Nucleic Acids Res; 2011 Jul; 39(13):5800-12. PubMed ID: 21427082 [TBL] [Abstract][Full Text] [Related]
10. Structure of a covalent DNA minor groove adduct with a pyrrolobenzodiazepine dimer: evidence for sequence-specific interstrand cross-linking. Jenkins TC; Hurley LH; Neidle S; Thurston DE J Med Chem; 1994 Dec; 37(26):4529-37. PubMed ID: 7799403 [TBL] [Abstract][Full Text] [Related]
11. Determination of chemically reduced pyrrolobenzodiazepine SJG-136 in human plasma by HPLC-MS/MS: application to an anticancer phase I dose escalation study. Wade Calcutt M; Lee W; Puzanov I; Rothenberg ML; Hachey DL J Mass Spectrom; 2008 Jan; 43(1):42-52. PubMed ID: 17683023 [TBL] [Abstract][Full Text] [Related]
12. Interactions of pyrrolobenzodiazepine dimers and duplex DNA from methicillin-resistant Staphylococcus aureus. Hadjivassileva T; Stapleton PD; Thurston DE; Taylor PW Int J Antimicrob Agents; 2007 Jun; 29(6):672-8. PubMed ID: 17350809 [TBL] [Abstract][Full Text] [Related]
13. Molecular interaction of DNA with bisplatinum(II) complexes having bis(vicinal 1,2-diamines) as ligand. Büning H; Altman J; Beck W; Zorbas H Biochemistry; 1997 Sep; 36(38):11408-18. PubMed ID: 9298960 [TBL] [Abstract][Full Text] [Related]
14. Unique properties of DNA interstrand cross-links of antitumor oxaliplatin and the effect of chirality of the carrier ligand. Kasparkova J; Vojtiskova M; Natile G; Brabec V Chemistry; 2008; 14(4):1330-41. PubMed ID: 18022972 [TBL] [Abstract][Full Text] [Related]
15. Linker length modulates DNA cross-linking reactivity and cytotoxic potency of C8/C8' ether-linked C2-exo-unsaturated pyrrolo[2,1-c][1,4]benzodiazepine (PBD) dimers. Gregson SJ; Howard PW; Gullick DR; Hamaguchi A; Corcoran KE; Brooks NA; Hartley JA; Jenkins TC; Patel S; Guille MJ; Thurston DE J Med Chem; 2004 Feb; 47(5):1161-74. PubMed ID: 14971896 [TBL] [Abstract][Full Text] [Related]
16. Reaching for the other side: generating sequence-dependent interstrand cross-links with 5-bromodeoxyuridine and gamma-rays. Dextraze ME; Cecchini S; Bergeron F; Girouard S; Turcotte K; Wagner JR; Hunting DJ Biochemistry; 2009 Mar; 48(9):2005-11. PubMed ID: 19216505 [TBL] [Abstract][Full Text] [Related]
17. Fast interstrand cross-linking of cisplatin-DNA monoadducts compared with intrastrand chelation: a kinetic study using hairpin-stabilized duplex oligonucleotides. Monjardet-Bas V; Chottard JC; Kozelka J Chemistry; 2002 Mar; 8(5):1144-50. PubMed ID: 11891902 [TBL] [Abstract][Full Text] [Related]
18. Formation of inter- and intrastrand imine type DNA-DNA cross-links through secondary reactions of aldehydic adducts. Sanchez AM; Kozekov ID; Harris TM; Lloyd RS Chem Res Toxicol; 2005 Nov; 18(11):1683-90. PubMed ID: 16300377 [TBL] [Abstract][Full Text] [Related]
19. Recognition of DNA interstrand cross-link of antitumor cisplatin by HMGB1 protein. Kasparkova J; Delalande O; Stros M; Elizondo-Riojas MA; Vojtiskova M; Kozelka J; Brabec V Biochemistry; 2003 Feb; 42(5):1234-44. PubMed ID: 12564926 [TBL] [Abstract][Full Text] [Related]
20. Preliminary pharmacokinetic and bioanalytical studies of SJG-136 (NSC 694501), a sequence-selective pyrrolobenzodiazepine dimer DNA-cross-linking agent. Wilkinson GP; Taylor JP; Shnyder S; Cooper P; Howard PW; Thurston DE; Jenkins TC; Loadman PM Invest New Drugs; 2004 Aug; 22(3):231-40. PubMed ID: 15122070 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]