398 related articles for article (PubMed ID: 19726885)
1. The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling.
Micalizzi DS; Christensen KL; Jedlicka P; Coletta RD; Barón AE; Harrell JC; Horwitz KB; Billheimer D; Heichman KA; Welm AL; Schiemann WP; Ford HL
J Clin Invest; 2009 Sep; 119(9):2678-90. PubMed ID: 19726885
[TBL] [Abstract][Full Text] [Related]
2. Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition.
McCoy EL; Iwanaga R; Jedlicka P; Abbey NS; Chodosh LA; Heichman KA; Welm AL; Ford HL
J Clin Invest; 2009 Sep; 119(9):2663-77. PubMed ID: 19726883
[TBL] [Abstract][Full Text] [Related]
3. Homeoprotein Six1 increases TGF-beta type I receptor and converts TGF-beta signaling from suppressive to supportive for tumor growth.
Micalizzi DS; Wang CA; Farabaugh SM; Schiemann WP; Ford HL
Cancer Res; 2010 Dec; 70(24):10371-80. PubMed ID: 21056993
[TBL] [Abstract][Full Text] [Related]
4. Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and transforming growth factor-beta signaling pathways.
Iwanaga R; Wang CA; Micalizzi DS; Harrell JC; Jedlicka P; Sartorius CA; Kabos P; Farabaugh SM; Bradford AP; Ford HL
Breast Cancer Res; 2012 Jul; 14(4):R100. PubMed ID: 22765220
[TBL] [Abstract][Full Text] [Related]
5. Defining a role for the homeoprotein Six1 in EMT and mammary tumorigenesis.
Radisky DC
J Clin Invest; 2009 Sep; 119(9):2528-31. PubMed ID: 19726879
[TBL] [Abstract][Full Text] [Related]
6. Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial-mesenchymal transition, and cancer stem cell properties.
Farabaugh SM; Micalizzi DS; Jedlicka P; Zhao R; Ford HL
Oncogene; 2012 Feb; 31(5):552-62. PubMed ID: 21706047
[TBL] [Abstract][Full Text] [Related]
7. SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer.
Wang CA; Jedlicka P; Patrick AN; Micalizzi DS; Lemmer KC; Deitsch E; Casás-Selves M; Harrell JC; Ford HL
J Clin Invest; 2012 May; 122(5):1895-906. PubMed ID: 22466647
[TBL] [Abstract][Full Text] [Related]
8. The miR-106b-25 cluster targets Smad7, activates TGF-β signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer.
Smith AL; Iwanaga R; Drasin DJ; Micalizzi DS; Vartuli RL; Tan AC; Ford HL
Oncogene; 2012 Dec; 31(50):5162-71. PubMed ID: 22286770
[TBL] [Abstract][Full Text] [Related]
9. The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells.
Taylor MA; Parvani JG; Schiemann WP
J Mammary Gland Biol Neoplasia; 2010 Jun; 15(2):169-90. PubMed ID: 20467795
[TBL] [Abstract][Full Text] [Related]
10. Six1 promotes epithelial-mesenchymal transition and malignant conversion in human papillomavirus type 16-immortalized human keratinocytes.
Xu H; Zhang Y; Altomare D; Peña MM; Wan F; Pirisi L; Creek KE
Carcinogenesis; 2014 Jun; 35(6):1379-88. PubMed ID: 24574515
[TBL] [Abstract][Full Text] [Related]
11. Transcription factor PREP1 induces EMT and metastasis by controlling the TGF-β-SMAD3 pathway in non-small cell lung adenocarcinoma.
Risolino M; Mandia N; Iavarone F; Dardaei L; Longobardi E; Fernandez S; Talotta F; Bianchi F; Pisati F; Spaggiari L; Harter PN; Mittelbronn M; Schulte D; Incoronato M; Di Fiore PP; Blasi F; Verde P
Proc Natl Acad Sci U S A; 2014 Sep; 111(36):E3775-84. PubMed ID: 25157139
[TBL] [Abstract][Full Text] [Related]
12. Autocrine PDGFR signaling promotes mammary cancer metastasis.
Jechlinger M; Sommer A; Moriggl R; Seither P; Kraut N; Capodiecci P; Donovan M; Cordon-Cardo C; Beug H; Grünert S
J Clin Invest; 2006 Jun; 116(6):1561-70. PubMed ID: 16741576
[TBL] [Abstract][Full Text] [Related]
13. An novel inhibitor of TGF-β type I receptor, IN-1130, blocks breast cancer lung metastasis through inhibition of epithelial-mesenchymal transition.
Park CY; Min KN; Son JY; Park SY; Nam JS; Kim DK; Sheen YY
Cancer Lett; 2014 Aug; 351(1):72-80. PubMed ID: 24887560
[TBL] [Abstract][Full Text] [Related]
14. MiR-203a-3p regulates TGF-β1-induced epithelial-mesenchymal transition (EMT) in asthma by regulating Smad3 pathway through SIX1.
Fan Q; Jian Y
Biosci Rep; 2020 Feb; 40(2):. PubMed ID: 32065213
[TBL] [Abstract][Full Text] [Related]
15. Identification of a Small-Molecule Inhibitor That Disrupts the SIX1/EYA2 Complex, EMT, and Metastasis.
Zhou H; Blevins MA; Hsu JY; Kong D; Galbraith MD; Goodspeed A; Culp-Hill R; Oliphant MUJ; Ramirez D; Zhang L; Trinidad-Pineiro J; Mathews Griner L; King R; Barnaeva E; Hu X; Southall NT; Ferrer M; Gustafson DL; Regan DP; D'Alessandro A; Costello JC; Patnaik S; Marugan J; Zhao R; Ford HL
Cancer Res; 2020 Jun; 80(12):2689-2702. PubMed ID: 32341035
[TBL] [Abstract][Full Text] [Related]
16. [Effect of Six1,TGF-β,VEGF-C that promoting tumor lymphangiogenesis in human laryngeal carcinoma xenografts in nude mice].
Wang L; Zhu MS; Tian JH; Xue HT; Liu HL; Zhang JH
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2016 Dec; 30(24):1960-1964. PubMed ID: 29798275
[No Abstract] [Full Text] [Related]
17. Engagement of I-branching {beta}-1, 6-N-acetylglucosaminyltransferase 2 in breast cancer metastasis and TGF-{beta} signaling.
Zhang H; Meng F; Wu S; Kreike B; Sethi S; Chen W; Miller FR; Wu G
Cancer Res; 2011 Jul; 71(14):4846-56. PubMed ID: 21750175
[TBL] [Abstract][Full Text] [Related]
18. HER-2 overexpression differentially alters transforming growth factor-beta responses in luminal versus mesenchymal human breast cancer cells.
Wilson CA; Cajulis EE; Green JL; Olsen TM; Chung YA; Damore MA; Dering J; Calzone FJ; Slamon DJ
Breast Cancer Res; 2005; 7(6):R1058-79. PubMed ID: 16457687
[TBL] [Abstract][Full Text] [Related]
19. A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition.
Vincent T; Neve EP; Johnson JR; Kukalev A; Rojo F; Albanell J; Pietras K; Virtanen I; Philipson L; Leopold PL; Crystal RG; de Herreros AG; Moustakas A; Pettersson RF; Fuxe J
Nat Cell Biol; 2009 Aug; 11(8):943-50. PubMed ID: 19597490
[TBL] [Abstract][Full Text] [Related]
20. Loss of RAB1B promotes triple-negative breast cancer metastasis by activating TGF-β/SMAD signaling.
Jiang HL; Sun HF; Gao SP; Li LD; Hu X; Wu J; Jin W
Oncotarget; 2015 Jun; 6(18):16352-65. PubMed ID: 25970785
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
