97 related articles for article (PubMed ID: 19729231)
1. A class of novel N-(3S-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)-L-amino acid derivatives: their synthesis, anti-thrombotic activity evaluation, and 3D QSAR analysis.
Cheng S; Zhang X; Wang W; Zhao M; Zheng M; Chang HW; Wu J; Peng S
Eur J Med Chem; 2009 Dec; 44(12):4904-19. PubMed ID: 19729231
[TBL] [Abstract][Full Text] [Related]
2. (3S)-N-(L-Aminoacyl)-1,2,3,4-tetrahydroisoquinolines, a class of novel antithrombotic agents: synthesis, bioassay, 3D QSAR, and ADME analysis.
Zheng M; Zhang X; Zhao M; Chang HW; Wang W; Wang Y; Peng S
Bioorg Med Chem; 2008 Nov; 16(21):9574-87. PubMed ID: 18835178
[TBL] [Abstract][Full Text] [Related]
3. 2-Substituted (S)-2-(3,3-dimethyl-1-oxo-10,10a-dihydroimidazo[1,5-b]isoquinolin-2(1H,3H,5H)-yl)acetic acids: Conformational prediction, synthesis, anti-thrombotic and vasodilative evaluation.
Wang H; Peng L; Zhao M; Liu J; Zhang X; Wang Y; Wu J; Li L; Peng S
Bioorg Med Chem; 2011 Jan; 19(2):871-82. PubMed ID: 21193315
[TBL] [Abstract][Full Text] [Related]
4. A class of oral N-[(1S,3S)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carbonyl]- N'-(amino-acid-acyl)hydrazine: discovery, synthesis, in vitro anti-platelet aggregation/in vivo anti-thrombotic evaluation and 3D QSAR analysis.
Yao K; Zhao M; Zhang X; Wang Y; Li L; Zheng M; Peng S
Eur J Med Chem; 2011 Aug; 46(8):3237-49. PubMed ID: 21571404
[TBL] [Abstract][Full Text] [Related]
5. A class of 3S-2-aminoacyltetrahydro-beta-carboline-3-carboxylic acids: their facile synthesis, inhibition for platelet activation, and high in vivo anti-thrombotic potency.
Liu J; Jiang X; Zhao M; Zhang X; Zheng M; Peng L; Peng S
J Med Chem; 2010 Apr; 53(8):3106-16. PubMed ID: 20329729
[TBL] [Abstract][Full Text] [Related]
6. 2,3-Diamino acid modifying 3S-tetrahydroisoquinoline-3-carboxylic acids: leading to a class of novel agents with highly unfolded conformation, selective in vitro anti-platelet aggregation and potent in vivo anti-thrombotic activity.
Zhang X; Wang W; Cheng S; Zhao M; Zheng M; Chang HW; Wu J; Peng S
Bioorg Med Chem; 2010 Feb; 18(4):1536-54. PubMed ID: 20122838
[TBL] [Abstract][Full Text] [Related]
7. A class of novel N-(1-methyl-β-carboline-3-carbonyl)-N'-(aminoacid-acyl)-hydrazines: aromatization leaded design, synthesis, in vitro anti-platelet aggregation/in vivo anti-thrombotic evaluation and 3D QSAR analysis.
Li C; Zhang X; Zhao M; Wang Y; Wu J; Liu J; Zheng M; Peng S
Eur J Med Chem; 2011 Nov; 46(11):5598-608. PubMed ID: 21983333
[TBL] [Abstract][Full Text] [Related]
8. The application of tetrahydroisoquinoline-3-carbonyl-TARGD(F)F as an anti-thrombotic agent having dual mechanisms of action.
Yang G; Zhu H; Zhao M; Wu J; Wang Y; Wang Y; Zheng M; Chen M; Liu J; Peng S
Mol Biosyst; 2012 Oct; 8(10):2672-9. PubMed ID: 22801714
[TBL] [Abstract][Full Text] [Related]
9. A new class of anti-thrombosis hexahydropyrazino-[1',2':1,6]pyrido-[3,4-b]-indole-1,4-dions: design, synthesis, logK determination, and QSAR analysis.
Liu J; Wu G; Cui G; Wang WX; Zhao M; Wang C; Zhang Z; Peng S
Bioorg Med Chem; 2007 Sep; 15(17):5672-93. PubMed ID: 17590343
[TBL] [Abstract][Full Text] [Related]
10. (1R,3S)-THCCA-Asn: To show the discovery of selective inhibitor of thrombin by successfully combining virtual screening and biological assay.
Zhang X; Yang Y; Wang Y; Wu J; Fang Q; Wang Y; Zhao M; Peng S
Eur J Med Chem; 2022 Nov; 242():114681. PubMed ID: 36001936
[TBL] [Abstract][Full Text] [Related]
11. pH-Dependent nanostructure based on isoquinoline-cyclodextrin conjugate for thrombosis therapy.
Li L; Zhao M; Li W; Wang Y; Liu C; Zhang Z; Su S; Peng S
Nanomedicine; 2012 Oct; 8(7):1216-22. PubMed ID: 22248818
[TBL] [Abstract][Full Text] [Related]
12. Effects of higenamine and its 1-naphthyl analogs, YS-49 and YS-51, on platelet TXA2 synthesis and aggregation.
Pyo MK; Kim JM; Jin JL; Chang KC; Lee DH; Yun-Choi HS
Thromb Res; 2007; 120(1):81-6. PubMed ID: 17020781
[TBL] [Abstract][Full Text] [Related]
13. Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates.
Bi W; Bi L; Cai J; Liu S; Peng S; Fischer NO; Tok JB; Wang G
Bioorg Med Chem Lett; 2006 Sep; 16(17):4523-7. PubMed ID: 16797986
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis and evaluation of nitric oxide releasing derivatives of 3-n-butylphthalide as antiplatelet and antithrombotic agents.
Wang X; Li Y; Zhao Q; Min Z; Zhang C; Lai Y; Ji H; Peng S; Zhang Y
Org Biomol Chem; 2011 Aug; 9(16):5670-81. PubMed ID: 21706121
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and structure-activity relationships of novel selective factor Xa inhibitors with a tetrahydroisoquinoline ring.
Ueno H; Yokota K; Hoshi J; Yasue K; Hayashi M; Hase Y; Uchida I; Aisaka K; Katoh S; Cho H
J Med Chem; 2005 May; 48(10):3586-604. PubMed ID: 15887966
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and evaluation of anti-thrombotic activity of benzocoumarin amide derivatives.
Sashidhara KV; Palnati GR; Avula SR; Singh S; Jain M; Dikshit M
Bioorg Med Chem Lett; 2012 May; 22(9):3115-21. PubMed ID: 22483393
[TBL] [Abstract][Full Text] [Related]
17. Synthesis of new class dipeptide analogues with improved permeability and antithrombotic activity.
Zhao M; Bi L; Bi W; Wang C; Yang Z; Ju J; Peng S
Bioorg Med Chem; 2006 Jul; 14(14):4761-74. PubMed ID: 16616499
[TBL] [Abstract][Full Text] [Related]
18. A class of novel N-isoquinoline-3-carbonyl-L-amino acid benzylesters: synthesis, anti-tumor evaluation and 3D QSAR analysis.
Zheng M; Yang Y; Zhao M; Zhang X; Wu J; Chen G; Peng L; Wang Y; Peng S
Eur J Med Chem; 2011 May; 46(5):1672-81. PubMed ID: 21414693
[TBL] [Abstract][Full Text] [Related]
19. A class of novel carboline intercalators: Their synthesis, in vitro anti-proliferation, in vivo anti-tumor action, and 3D QSAR analysis.
Wu J; Li C; Zhao M; Wang W; Wang Y; Peng S
Bioorg Med Chem; 2010 Sep; 18(17):6220-9. PubMed ID: 20692841
[TBL] [Abstract][Full Text] [Related]
20. Anti-thrombotic and anti-inflammatory activities of protopine.
Saeed SA; Gilani AH; Majoo RU; Shah BH
Pharmacol Res; 1997 Jul; 36(1):1-7. PubMed ID: 9368908
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
