BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 19729306)

  • 1. Structure-based design of novel human Pin1 inhibitors (I).
    Guo C; Hou X; Dong L; Dagostino E; Greasley S; Ferre R; Marakovits J; Johnson MC; Matthews D; Mroczkowski B; Parge H; Vanarsdale T; Popoff I; Piraino J; Margosiak S; Thomson J; Los G; Murray BW
    Bioorg Med Chem Lett; 2009 Oct; 19(19):5613-6. PubMed ID: 19729306
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-guided design of alpha-amino acid-derived Pin1 inhibitors.
    Potter AJ; Ray S; Gueritz L; Nunns CL; Bryant CJ; Scrace SF; Matassova N; Baker L; Dokurno P; Robinson DA; Surgenor AE; Davis B; Murray JB; Richardson CM; Moore JD
    Bioorg Med Chem Lett; 2010 Jan; 20(2):586-90. PubMed ID: 19969456
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-based design of novel human Pin1 inhibitors (II).
    Dong L; Marakovits J; Hou X; Guo C; Greasley S; Dagostino E; Ferre R; Johnson MC; Kraynov E; Thomson J; Pathak V; Murray BW
    Bioorg Med Chem Lett; 2010 Apr; 20(7):2210-4. PubMed ID: 20207139
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-based design of novel human Pin1 inhibitors (III): optimizing affinity beyond the phosphate recognition pocket.
    Guo C; Hou X; Dong L; Marakovits J; Greasley S; Dagostino E; Ferre R; Johnson MC; Humphries PS; Li H; Paderes GD; Piraino J; Kraynov E; Murray BW
    Bioorg Med Chem Lett; 2014 Sep; 24(17):4187-91. PubMed ID: 25091930
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Design, synthesis and biological evaluation of novel diaryl ethers bearing a pyrimidine motif as human Pin1 inhibitors].
    Xi YY; Jin J; Sun Y; Chen XG; Song HR; Xu BL
    Yao Xue Xue Bao; 2013 Aug; 48(8):1266-72. PubMed ID: 24187834
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of novel human Pin1 inhibitors with benzophenone skeleton.
    Liu C; Jin J; Chen L; Zhou J; Chen X; Fu D; Song H; Xu B
    Bioorg Med Chem; 2012 May; 20(9):2992-9. PubMed ID: 22459212
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and biological evaluation of novel quinazoline-derived human Pin1 inhibitors.
    Zhu L; Jin J; Liu C; Zhang C; Sun Y; Guo Y; Fu D; Chen X; Xu B
    Bioorg Med Chem; 2011 May; 19(9):2797-807. PubMed ID: 21504850
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of the novel elemonic acid derivatives as Pin1 inhibitors.
    Li X; Li L; Zhou Q; Zhang N; Zhang S; Zhao R; Liu D; Jing Y; Zhao L
    Bioorg Med Chem Lett; 2014 Dec; 24(24):5612-5615. PubMed ID: 25466185
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Recent advances in the study of pin1 and its inhibitors].
    Zhang CJ; Zhang ZH; Xu BL; Wang YL
    Yao Xue Xue Bao; 2008 Jan; 43(1):9-17. PubMed ID: 18357725
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nanomolar inhibitors of the peptidyl prolyl cis/trans isomerase Pin1 from combinatorial peptide libraries.
    Wildemann D; Erdmann F; Alvarez BH; Stoller G; Zhou XZ; Fanghänel J; Schutkowski M; Lu KP; Fischer G
    J Med Chem; 2006 Apr; 49(7):2147-50. PubMed ID: 16570909
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural basis for high-affinity peptide inhibition of human Pin1.
    Zhang Y; Daum S; Wildemann D; Zhou XZ; Verdecia MA; Bowman ME; Lücke C; Hunter T; Lu KP; Fischer G; Noel JP
    ACS Chem Biol; 2007 May; 2(5):320-8. PubMed ID: 17518432
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and biological evaluation of novel thiazole-based derivatives as human Pin1 inhibitors.
    Du L; Wang X; Cui G; Xu B
    Bioorg Med Chem; 2021 Jan; 29():115878. PubMed ID: 33246256
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of prolyl isomerase pin1 in pathogenesis of diseases and remedy for the diseases from natural products.
    Takahashi K; Shimizu T; Kosaka K; Hidaka M; Uchida C; Uchida T
    Curr Drug Targets; 2014; 15(10):973-81. PubMed ID: 25182609
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dipentamethylene thiuram monosulfide is a novel inhibitor of Pin1.
    Tatara Y; Lin YC; Bamba Y; Mori T; Uchida T
    Biochem Biophys Res Commun; 2009 Jul; 384(3):394-8. PubMed ID: 19422802
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery and characterization of a nonphosphorylated cyclic peptide inhibitor of the peptidylprolyl isomerase, Pin1.
    Duncan KE; Dempsey BR; Killip LE; Adams J; Bailey ML; Lajoie GA; Litchfield DW; Brandl CJ; Shaw GS; Shilton BH
    J Med Chem; 2011 Jun; 54(11):3854-65. PubMed ID: 21545152
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Membrane permeable cyclic peptidyl inhibitors against human Peptidylprolyl Isomerase Pin1.
    Liu T; Liu Y; Kao HY; Pei D
    J Med Chem; 2010 Mar; 53(6):2494-501. PubMed ID: 20180533
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Peptidyl prolyl isomerase Pin1-inhibitory activity of D-glutamic and D-aspartic acid derivatives bearing a cyclic aliphatic amine moiety.
    Nakagawa H; Seike S; Sugimoto M; Ieda N; Kawaguchi M; Suzuki T; Miyata N
    Bioorg Med Chem Lett; 2015 Dec; 25(23):5619-24. PubMed ID: 26508545
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A dual inhibitor against prolyl isomerase Pin1 and cyclophilin discovered by a novel real-time fluorescence detection method.
    Mori T; Hidaka M; Lin YC; Yoshizawa I; Okabe T; Egashira S; Kojima H; Nagano T; Koketsu M; Takamiya M; Uchida T
    Biochem Biophys Res Commun; 2011 Mar; 406(3):439-43. PubMed ID: 21333629
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Pin1: a multi-talented peptidyl prolyl cis-trans isomerase and a promising therapeutic target for human cancers].
    Marsolier J; Weitzman JB
    Med Sci (Paris); 2014; 30(8-9):772-8. PubMed ID: 25174754
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A reduced-amide inhibitor of Pin1 binds in a conformation resembling a twisted-amide transition state.
    Xu GG; Zhang Y; Mercedes-Camacho AY; Etzkorn FA
    Biochemistry; 2011 Nov; 50(44):9545-50. PubMed ID: 21980916
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.