179 related articles for article (PubMed ID: 19734844)
1. MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa.
Hawkins NJ; Lee JH; Wong JJ; Kwok CT; Ward RL; Hitchins MP
Mod Pathol; 2009 Dec; 22(12):1588-99. PubMed ID: 19734844
[TBL] [Abstract][Full Text] [Related]
2. MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer.
Ogino S; Hazra A; Tranah GJ; Kirkner GJ; Kawasaki T; Nosho K; Ohnishi M; Suemoto Y; Meyerhardt JA; Hunter DJ; Fuchs CS
Carcinogenesis; 2007 Sep; 28(9):1985-90. PubMed ID: 17621591
[TBL] [Abstract][Full Text] [Related]
3. Methylation pattern of the O6-methylguanine-DNA methyltransferase gene in colon during progressive colorectal tumorigenesis.
Nagasaka T; Goel A; Notohara K; Takahata T; Sasamoto H; Uchida T; Nishida N; Tanaka N; Boland CR; Matsubara N
Int J Cancer; 2008 Jun; 122(11):2429-36. PubMed ID: 18240147
[TBL] [Abstract][Full Text] [Related]
4. The MGMT promoter SNP rs16906252 is a risk factor for MGMT methylation in glioblastoma and is predictive of response to temozolomide.
Rapkins RW; Wang F; Nguyen HN; Cloughesy TF; Lai A; Ha W; Nowak AK; Hitchins MP; McDonald KL
Neuro Oncol; 2015 Dec; 17(12):1589-98. PubMed ID: 25910840
[TBL] [Abstract][Full Text] [Related]
5. Kras gene mutation and RASSF1A, FHIT and MGMT gene promoter hypermethylation: indicators of tumor staging and metastasis in adenocarcinomatous sporadic colorectal cancer in Indian population.
Sinha R; Hussain S; Mehrotra R; Kumar RS; Kumar K; Pande P; Doval DC; Basir SF; Bharadwaj M
PLoS One; 2013; 8(4):e60142. PubMed ID: 23573237
[TBL] [Abstract][Full Text] [Related]
6. Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma.
Suehiro Y; Wong CW; Chirieac LR; Kondo Y; Shen L; Webb CR; Chan YW; Chan AS; Chan TL; Wu TT; Rashid A; Hamanaka Y; Hinoda Y; Shannon RL; Wang X; Morris J; Issa JP; Yuen ST; Leung SY; Hamilton SR
Clin Cancer Res; 2008 May; 14(9):2560-9. PubMed ID: 18451217
[TBL] [Abstract][Full Text] [Related]
7. Methylation of MGMT in malignant pleural mesothelioma occurs in a subset of patients and is associated with the T allele of the rs16906252 MGMT promoter SNP.
Kristensen LS; Nielsen HM; Hager H; Hansen LL
Lung Cancer; 2011 Feb; 71(2):130-6. PubMed ID: 20627446
[TBL] [Abstract][Full Text] [Related]
8. The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas.
Leng S; Bernauer AM; Hong C; Do KC; Yingling CM; Flores KG; Tessema M; Tellez CS; Willink RP; Burki EA; Picchi MA; Stidley CA; Prados MD; Costello JF; Gilliland FD; Crowell RE; Belinsky SA
Clin Cancer Res; 2011 Apr; 17(7):2014-23. PubMed ID: 21355081
[TBL] [Abstract][Full Text] [Related]
9. MGMT and MLH1 promoter methylation versus APC, KRAS and BRAF gene mutations in colorectal cancer: indications for distinct pathways and sequence of events.
de Vogel S; Weijenberg MP; Herman JG; Wouters KA; de Goeij AF; van den Brandt PA; de Bruïne AP; van Engeland M
Ann Oncol; 2009 Jul; 20(7):1216-22. PubMed ID: 19164452
[TBL] [Abstract][Full Text] [Related]
10. Impact of catechol-O-methyltransferase gene variants on methylation status of P16 and MGMT genes and their downregulation in colorectal cancer.
Wani HA; Majid S; Bhat AA; Amin S; Farooq R; Bhat SA; Naikoo NA; Beigh MA; Kadla SA
Eur J Cancer Prev; 2019 Mar; 28(2):68-75. PubMed ID: 30379684
[TBL] [Abstract][Full Text] [Related]
11. Methylation of MGMT and ADAMTS14 in normal colon mucosa: biomarkers of a field defect for cancerization preferentially targeting elder African-Americans.
Alonso S; Dai Y; Yamashita K; Horiuchi S; Dai T; Matsunaga A; Sánchez-Muñoz R; Bilbao-Sieyro C; Díaz-Chico JC; Chernov AV; Strongin AY; Perucho M
Oncotarget; 2015 Feb; 6(5):3420-31. PubMed ID: 25638164
[TBL] [Abstract][Full Text] [Related]
12. Promoter methylation status of hMLH1, hMSH2, and MGMT genes in colorectal cancer associated with adenoma-carcinoma sequence.
Lee KH; Lee JS; Nam JH; Choi C; Lee MC; Park CS; Juhng SW; Lee JH
Langenbecks Arch Surg; 2011 Oct; 396(7):1017-26. PubMed ID: 21706233
[TBL] [Abstract][Full Text] [Related]
13. MGMT promoter methylation, loss of expression and prognosis in 855 colorectal cancers.
Shima K; Morikawa T; Baba Y; Nosho K; Suzuki M; Yamauchi M; Hayashi M; Giovannucci E; Fuchs CS; Ogino S
Cancer Causes Control; 2011 Feb; 22(2):301-9. PubMed ID: 21140203
[TBL] [Abstract][Full Text] [Related]
14. Methylation of the MGMT and p16 genes in sporadic colorectal carcinoma and corresponding normal colonic mucosa.
Krakowczyk L; Strzelczyk JK; Adamek B; Zalewska-Ziob M; Arendt J; Półtorak S; Maciejewski B; Wiczkowski A
Med Sci Monit; 2008 Oct; 14(10):BR219-25. PubMed ID: 18830187
[TBL] [Abstract][Full Text] [Related]
15. MGMT promoter methylation and field defect in sporadic colorectal cancer.
Shen L; Kondo Y; Rosner GL; Xiao L; Hernandez NS; Vilaythong J; Houlihan PS; Krouse RS; Prasad AR; Einspahr JG; Buckmeier J; Alberts DS; Hamilton SR; Issa JP
J Natl Cancer Inst; 2005 Sep; 97(18):1330-8. PubMed ID: 16174854
[TBL] [Abstract][Full Text] [Related]
16. SNP rs16906252C>T Is an Expression and Methylation Quantitative Trait Locus Associated with an Increased Risk of Developing MGMT-Methylated Colorectal Cancer.
Kuroiwa-Trzmielina J; Wang F; Rapkins RW; Ward RL; Buchanan DD; Win AK; Clendenning M; Rosty C; Southey MC; Winship IM; Hopper JL; Jenkins MA; Olivier J; Hawkins NJ; Hitchins MP
Clin Cancer Res; 2016 Dec; 22(24):6266-6277. PubMed ID: 27267851
[TBL] [Abstract][Full Text] [Related]
17. Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features.
Rosty C; Young JP; Walsh MD; Clendenning M; Walters RJ; Pearson S; Pavluk E; Nagler B; Pakenas D; Jass JR; Jenkins MA; Win AK; Southey MC; Parry S; Hopper JL; Giles GG; Williamson E; English DR; Buchanan DD
Mod Pathol; 2013 Jun; 26(6):825-34. PubMed ID: 23348904
[TBL] [Abstract][Full Text] [Related]
18. Gene methylation of SFRP2, P16, DAPK1, HIC1, and MGMT and KRAS mutations in sporadic colorectal cancer.
Pehlivan S; Artac M; Sever T; Bozcuk H; Kilincarslan C; Pehlivan M
Cancer Genet Cytogenet; 2010 Sep; 201(2):128-32. PubMed ID: 20682398
[TBL] [Abstract][Full Text] [Related]
19. Detection of MGMT promoter methylation in normal individuals is strongly associated with the T allele of the rs16906252 MGMT promoter single nucleotide polymorphism.
Candiloro IL; Dobrovic A
Cancer Prev Res (Phila); 2009 Oct; 2(10):862-7. PubMed ID: 19789298
[TBL] [Abstract][Full Text] [Related]
20. Molecular features of colorectal hyperplastic polyps and sessile serrated adenoma/polyps from Korea.
Kim KM; Lee EJ; Ha S; Kang SY; Jang KT; Park CK; Kim JY; Kim YH; Chang DK; Odze RD
Am J Surg Pathol; 2011 Sep; 35(9):1274-86. PubMed ID: 21836485
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]