These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 19734844)

  • 1. MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa.
    Hawkins NJ; Lee JH; Wong JJ; Kwok CT; Ward RL; Hitchins MP
    Mod Pathol; 2009 Dec; 22(12):1588-99. PubMed ID: 19734844
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer.
    Ogino S; Hazra A; Tranah GJ; Kirkner GJ; Kawasaki T; Nosho K; Ohnishi M; Suemoto Y; Meyerhardt JA; Hunter DJ; Fuchs CS
    Carcinogenesis; 2007 Sep; 28(9):1985-90. PubMed ID: 17621591
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Methylation pattern of the O6-methylguanine-DNA methyltransferase gene in colon during progressive colorectal tumorigenesis.
    Nagasaka T; Goel A; Notohara K; Takahata T; Sasamoto H; Uchida T; Nishida N; Tanaka N; Boland CR; Matsubara N
    Int J Cancer; 2008 Jun; 122(11):2429-36. PubMed ID: 18240147
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The MGMT promoter SNP rs16906252 is a risk factor for MGMT methylation in glioblastoma and is predictive of response to temozolomide.
    Rapkins RW; Wang F; Nguyen HN; Cloughesy TF; Lai A; Ha W; Nowak AK; Hitchins MP; McDonald KL
    Neuro Oncol; 2015 Dec; 17(12):1589-98. PubMed ID: 25910840
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Kras gene mutation and RASSF1A, FHIT and MGMT gene promoter hypermethylation: indicators of tumor staging and metastasis in adenocarcinomatous sporadic colorectal cancer in Indian population.
    Sinha R; Hussain S; Mehrotra R; Kumar RS; Kumar K; Pande P; Doval DC; Basir SF; Bharadwaj M
    PLoS One; 2013; 8(4):e60142. PubMed ID: 23573237
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma.
    Suehiro Y; Wong CW; Chirieac LR; Kondo Y; Shen L; Webb CR; Chan YW; Chan AS; Chan TL; Wu TT; Rashid A; Hamanaka Y; Hinoda Y; Shannon RL; Wang X; Morris J; Issa JP; Yuen ST; Leung SY; Hamilton SR
    Clin Cancer Res; 2008 May; 14(9):2560-9. PubMed ID: 18451217
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Methylation of MGMT in malignant pleural mesothelioma occurs in a subset of patients and is associated with the T allele of the rs16906252 MGMT promoter SNP.
    Kristensen LS; Nielsen HM; Hager H; Hansen LL
    Lung Cancer; 2011 Feb; 71(2):130-6. PubMed ID: 20627446
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas.
    Leng S; Bernauer AM; Hong C; Do KC; Yingling CM; Flores KG; Tessema M; Tellez CS; Willink RP; Burki EA; Picchi MA; Stidley CA; Prados MD; Costello JF; Gilliland FD; Crowell RE; Belinsky SA
    Clin Cancer Res; 2011 Apr; 17(7):2014-23. PubMed ID: 21355081
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MGMT and MLH1 promoter methylation versus APC, KRAS and BRAF gene mutations in colorectal cancer: indications for distinct pathways and sequence of events.
    de Vogel S; Weijenberg MP; Herman JG; Wouters KA; de Goeij AF; van den Brandt PA; de Bruïne AP; van Engeland M
    Ann Oncol; 2009 Jul; 20(7):1216-22. PubMed ID: 19164452
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Impact of catechol-O-methyltransferase gene variants on methylation status of P16 and MGMT genes and their downregulation in colorectal cancer.
    Wani HA; Majid S; Bhat AA; Amin S; Farooq R; Bhat SA; Naikoo NA; Beigh MA; Kadla SA
    Eur J Cancer Prev; 2019 Mar; 28(2):68-75. PubMed ID: 30379684
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Methylation of MGMT and ADAMTS14 in normal colon mucosa: biomarkers of a field defect for cancerization preferentially targeting elder African-Americans.
    Alonso S; Dai Y; Yamashita K; Horiuchi S; Dai T; Matsunaga A; Sánchez-Muñoz R; Bilbao-Sieyro C; Díaz-Chico JC; Chernov AV; Strongin AY; Perucho M
    Oncotarget; 2015 Feb; 6(5):3420-31. PubMed ID: 25638164
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Promoter methylation status of hMLH1, hMSH2, and MGMT genes in colorectal cancer associated with adenoma-carcinoma sequence.
    Lee KH; Lee JS; Nam JH; Choi C; Lee MC; Park CS; Juhng SW; Lee JH
    Langenbecks Arch Surg; 2011 Oct; 396(7):1017-26. PubMed ID: 21706233
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MGMT promoter methylation, loss of expression and prognosis in 855 colorectal cancers.
    Shima K; Morikawa T; Baba Y; Nosho K; Suzuki M; Yamauchi M; Hayashi M; Giovannucci E; Fuchs CS; Ogino S
    Cancer Causes Control; 2011 Feb; 22(2):301-9. PubMed ID: 21140203
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Methylation of the MGMT and p16 genes in sporadic colorectal carcinoma and corresponding normal colonic mucosa.
    Krakowczyk L; Strzelczyk JK; Adamek B; Zalewska-Ziob M; Arendt J; Półtorak S; Maciejewski B; Wiczkowski A
    Med Sci Monit; 2008 Oct; 14(10):BR219-25. PubMed ID: 18830187
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MGMT promoter methylation and field defect in sporadic colorectal cancer.
    Shen L; Kondo Y; Rosner GL; Xiao L; Hernandez NS; Vilaythong J; Houlihan PS; Krouse RS; Prasad AR; Einspahr JG; Buckmeier J; Alberts DS; Hamilton SR; Issa JP
    J Natl Cancer Inst; 2005 Sep; 97(18):1330-8. PubMed ID: 16174854
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SNP rs16906252C>T Is an Expression and Methylation Quantitative Trait Locus Associated with an Increased Risk of Developing MGMT-Methylated Colorectal Cancer.
    Kuroiwa-Trzmielina J; Wang F; Rapkins RW; Ward RL; Buchanan DD; Win AK; Clendenning M; Rosty C; Southey MC; Winship IM; Hopper JL; Jenkins MA; Olivier J; Hawkins NJ; Hitchins MP
    Clin Cancer Res; 2016 Dec; 22(24):6266-6277. PubMed ID: 27267851
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features.
    Rosty C; Young JP; Walsh MD; Clendenning M; Walters RJ; Pearson S; Pavluk E; Nagler B; Pakenas D; Jass JR; Jenkins MA; Win AK; Southey MC; Parry S; Hopper JL; Giles GG; Williamson E; English DR; Buchanan DD
    Mod Pathol; 2013 Jun; 26(6):825-34. PubMed ID: 23348904
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gene methylation of SFRP2, P16, DAPK1, HIC1, and MGMT and KRAS mutations in sporadic colorectal cancer.
    Pehlivan S; Artac M; Sever T; Bozcuk H; Kilincarslan C; Pehlivan M
    Cancer Genet Cytogenet; 2010 Sep; 201(2):128-32. PubMed ID: 20682398
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Detection of MGMT promoter methylation in normal individuals is strongly associated with the T allele of the rs16906252 MGMT promoter single nucleotide polymorphism.
    Candiloro IL; Dobrovic A
    Cancer Prev Res (Phila); 2009 Oct; 2(10):862-7. PubMed ID: 19789298
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular features of colorectal hyperplastic polyps and sessile serrated adenoma/polyps from Korea.
    Kim KM; Lee EJ; Ha S; Kang SY; Jang KT; Park CK; Kim JY; Kim YH; Chang DK; Odze RD
    Am J Surg Pathol; 2011 Sep; 35(9):1274-86. PubMed ID: 21836485
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.