BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

395 related articles for article (PubMed ID: 19734945)

  • 1. Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation.
    Jacinto FV; Ballestar E; Esteller M
    Oncogene; 2009 Nov; 28(47):4212-24. PubMed ID: 19734945
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells.
    Stirzaker C; Song JZ; Davidson B; Clark SJ
    Cancer Res; 2004 Jun; 64(11):3871-7. PubMed ID: 15172996
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA methyltransferase-mediated transcriptional silencing in malignant glioma: a combined whole-genome microarray and promoter array analysis.
    Foltz G; Yoon JG; Lee H; Ryken TC; Sibenaller Z; Ehrich M; Hood L; Madan A
    Oncogene; 2009 Jul; 28(29):2667-77. PubMed ID: 19465937
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dominant-negative histone H3 lysine 27 mutant derepresses silenced tumor suppressor genes and reverses the drug-resistant phenotype in cancer cells.
    Abbosh PH; Montgomery JS; Starkey JA; Novotny M; Zuhowski EG; Egorin MJ; Moseman AP; Golas A; Brannon KM; Balch C; Huang TH; Nephew KP
    Cancer Res; 2006 Jun; 66(11):5582-91. PubMed ID: 16740693
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA methylation and gene silencing in cancer: which is the guilty party?
    Clark SJ; Melki J
    Oncogene; 2002 Aug; 21(35):5380-7. PubMed ID: 12154400
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 5'-azacytidine expression arrays.
    Cairns P
    Methods Mol Biol; 2009; 507():165-74. PubMed ID: 18987814
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of epigenetically masked tumor suppressor genes in endometrial cancer.
    Takai N; Kawamata N; Walsh CS; Gery S; Desmond JC; Whittaker S; Said JW; Popoviciu LM; Jones PA; Miyakawa I; Koeffler HP
    Mol Cancer Res; 2005 May; 3(5):261-9. PubMed ID: 15886297
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.
    Toyota M; Suzuki H; Sasaki Y; Maruyama R; Imai K; Shinomura Y; Tokino T
    Cancer Res; 2008 Jun; 68(11):4123-32. PubMed ID: 18519671
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors.
    Fraga MF; Herranz M; Espada J; Ballestar E; Paz MF; Ropero S; Erkek E; Bozdogan O; Peinado H; Niveleau A; Mao JH; Balmain A; Cano A; Esteller M
    Cancer Res; 2004 Aug; 64(16):5527-34. PubMed ID: 15313885
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning.
    Hinshelwood RA; Melki JR; Huschtscha LI; Paul C; Song JZ; Stirzaker C; Reddel RR; Clark SJ
    Hum Mol Genet; 2009 Aug; 18(16):3098-109. PubMed ID: 19477956
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gene silencing by DNA methylation in haematological malignancies.
    Boultwood J; Wainscoat JS
    Br J Haematol; 2007 Jul; 138(1):3-11. PubMed ID: 17489980
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases.
    Paz MF; Wei S; Cigudosa JC; Rodriguez-Perales S; Peinado MA; Huang TH; Esteller M
    Hum Mol Genet; 2003 Sep; 12(17):2209-19. PubMed ID: 12915469
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Epigenetic silencing of the MGMT gene in cancer.
    Soejima H; Zhao W; Mukai T
    Biochem Cell Biol; 2005 Aug; 83(4):429-37. PubMed ID: 16094446
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Halogenated thymidine analogues restore the expression of silenced genes without demethylation.
    Fan J; Kodama E; Koh Y; Nakao M; Matsuoka M
    Cancer Res; 2005 Aug; 65(15):6927-33. PubMed ID: 16061677
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A profile of methyl-CpG binding domain protein occupancy of hypermethylated promoter CpG islands of tumor suppressor genes in human cancer.
    Lopez-Serra L; Ballestar E; Fraga MF; Alaminos M; Setien F; Esteller M
    Cancer Res; 2006 Sep; 66(17):8342-6. PubMed ID: 16951140
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily.
    Du Y; Carling T; Fang W; Piao Z; Sheu JC; Huang S
    Cancer Res; 2001 Nov; 61(22):8094-9. PubMed ID: 11719434
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The necessity of a human epigenome project.
    Esteller M
    Carcinogenesis; 2006 Jun; 27(6):1121-5. PubMed ID: 16699174
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MUC1 expression is regulated by DNA methylation and histone H3 lysine 9 modification in cancer cells.
    Yamada N; Nishida Y; Tsutsumida H; Hamada T; Goto M; Higashi M; Nomoto M; Yonezawa S
    Cancer Res; 2008 Apr; 68(8):2708-16. PubMed ID: 18413738
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Methylation hot spots in the 5' flanking region denote silencing of the O6-methylguanine-DNA methyltransferase gene.
    Qian XC; Brent TP
    Cancer Res; 1997 Sep; 57(17):3672-7. PubMed ID: 9288770
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Concordant epigenetic silencing of transforming growth factor-beta signaling pathway genes occurs early in breast carcinogenesis.
    Hinshelwood RA; Huschtscha LI; Melki J; Stirzaker C; Abdipranoto A; Vissel B; Ravasi T; Wells CA; Hume DA; Reddel RR; Clark SJ
    Cancer Res; 2007 Dec; 67(24):11517-27. PubMed ID: 18089780
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.