170 related articles for article (PubMed ID: 19737573)
1. Exploring kainate receptor pharmacology using molecular dynamics simulations.
Postila PA; Swanson GT; Pentikäinen OT
Neuropharmacology; 2010 Feb; 58(2):515-27. PubMed ID: 19737573
[TBL] [Abstract][Full Text] [Related]
2. Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine.
Frydenvang K; Lash LL; Naur P; Postila PA; Pickering DS; Smith CM; Gajhede M; Sasaki M; Sakai R; Pentikaïnen OT; Swanson GT; Kastrup JS
J Biol Chem; 2009 May; 284(21):14219-29. PubMed ID: 19297335
[TBL] [Abstract][Full Text] [Related]
3. Binding and selectivity of the marine toxin neodysiherbaine A and its synthetic analogues to GluK1 and GluK2 kainate receptors.
Unno M; Shinohara M; Takayama K; Tanaka H; Teruya K; Doh-ura K; Sakai R; Sasaki M; Ikeda-Saito M
J Mol Biol; 2011 Oct; 413(3):667-83. PubMed ID: 21893069
[TBL] [Abstract][Full Text] [Related]
4. Pharmacological activity of C10-substituted analogs of the high-affinity kainate receptor agonist dysiherbaine.
Lash-Van Wyhe LL; Postila PA; Tsubone K; Sasaki M; Pentikäinen OT; Sakai R; Swanson GT
Neuropharmacology; 2010 Mar; 58(3):640-9. PubMed ID: 19962997
[TBL] [Abstract][Full Text] [Related]
5. Novel analogs and stereoisomers of the marine toxin neodysiherbaine with specificity for kainate receptors.
Lash LL; Sanders JM; Akiyama N; Shoji M; Postila P; Pentikäinen OT; Sasaki M; Sakai R; Swanson GT
J Pharmacol Exp Ther; 2008 Feb; 324(2):484-96. PubMed ID: 18032572
[TBL] [Abstract][Full Text] [Related]
6. Determination of binding site residues responsible for the subunit selectivity of novel marine-derived compounds on kainate receptors.
Sanders JM; Pentikäinen OT; Settimo L; Pentikäinen U; Shoji M; Sasaki M; Sakai R; Johnson MS; Swanson GT
Mol Pharmacol; 2006 Jun; 69(6):1849-60. PubMed ID: 16537793
[TBL] [Abstract][Full Text] [Related]
7. Subtype selective kainic acid receptor agonists: discovery and approaches to rational design.
Bunch L; Krogsgaard-Larsen P
Med Res Rev; 2009 Jan; 29(1):3-28. PubMed ID: 18623169
[TBL] [Abstract][Full Text] [Related]
8. Divergent pharmacological activity of novel marine-derived excitatory amino acids on glutamate receptors.
Sanders JM; Ito K; Settimo L; Pentikäinen OT; Shoji M; Sasaki M; Johnson MS; Sakai R; Swanson GT
J Pharmacol Exp Ther; 2005 Sep; 314(3):1068-78. PubMed ID: 15914675
[TBL] [Abstract][Full Text] [Related]
9. Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors.
Møllerud S; Pinto A; Marconi L; Frydenvang K; Thorsen TS; Laulumaa S; Venskutonytė R; Winther S; Moral AMC; Tamborini L; Conti P; Pickering DS; Kastrup JS
ACS Chem Neurosci; 2017 Sep; 8(9):2056-2064. PubMed ID: 28691798
[TBL] [Abstract][Full Text] [Related]
10. Lessons from crystal structures of kainate receptors.
Møllerud S; Frydenvang K; Pickering DS; Kastrup JS
Neuropharmacology; 2017 Jan; 112(Pt A):16-28. PubMed ID: 27236079
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, and biological evaluation of a scaffold for iGluR ligands based on the structure of (-)-dysiherbaine.
Cohen JL; Limon A; Miledi R; Chamberlin AR
Bioorg Med Chem Lett; 2006 Apr; 16(8):2189-94. PubMed ID: 16455241
[TBL] [Abstract][Full Text] [Related]
12. Full and partial agonism of ionotropic glutamate receptors indicated by molecular dynamics simulations.
Postila PA; Ylilauri M; Pentikäinen OT
J Chem Inf Model; 2011 May; 51(5):1037-47. PubMed ID: 21500800
[TBL] [Abstract][Full Text] [Related]
13. Luminescence resonance energy transfer investigation of conformational changes in the ligand binding domain of a kainate receptor.
Du M; Rambhadran A; Jayaraman V
J Biol Chem; 2008 Oct; 283(40):27074-8. PubMed ID: 18658129
[TBL] [Abstract][Full Text] [Related]
14. Structural and pharmacological characterization of phenylalanine-based AMPA receptor antagonists at kainate receptors.
Venskutonytė R; Frydenvang K; Valadés EA; Szymańska E; Johansen TN; Kastrup JS; Pickering DS
ChemMedChem; 2012 Oct; 7(10):1793-8. PubMed ID: 22407805
[TBL] [Abstract][Full Text] [Related]
15. Selective kainate receptor (GluK1) ligands structurally based upon 1H-cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization.
Venskutonyte R; Butini S; Coccone SS; Gemma S; Brindisi M; Kumar V; Guarino E; Maramai S; Valenti S; Amir A; Valadés EA; Frydenvang K; Kastrup JS; Novellino E; Campiani G; Pickering DS
J Med Chem; 2011 Jul; 54(13):4793-805. PubMed ID: 21619066
[TBL] [Abstract][Full Text] [Related]
16. Enantioselective Synthesis of (-)-Dysiherbaine.
Do H; Kang CW; Cho JH; Gilbertson SR
Org Lett; 2015 Aug; 17(16):3972-4. PubMed ID: 26258884
[TBL] [Abstract][Full Text] [Related]
17. Design, total synthesis, and biological evaluation of neodysiherbaine A derivative as potential probes.
Sasaki M; Tsubone K; Shoji M; Oikawa M; Shimamoto K; Sakai R
Bioorg Med Chem Lett; 2006 Nov; 16(22):5784-7. PubMed ID: 16949819
[TBL] [Abstract][Full Text] [Related]
18. N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists: X-ray Crystallography, Structure-Affinity Relationships, and in Vitro Pharmacology.
Pallesen J; Møllerud S; Frydenvang K; Pickering DS; Bornholdt J; Nielsen B; Pasini D; Han L; Marconi L; Kastrup JS; Johansen TN
ACS Chem Neurosci; 2019 Mar; 10(3):1841-1853. PubMed ID: 30620174
[TBL] [Abstract][Full Text] [Related]
19. Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate.
Venskutonytė R; Frydenvang K; Gajhede M; Bunch L; Pickering DS; Kastrup JS
J Struct Biol; 2011 Dec; 176(3):307-14. PubMed ID: 21907808
[TBL] [Abstract][Full Text] [Related]
20. Subtype selectivity and flexibility of ionotropic glutamate receptors upon antagonist ligand binding.
Pentikäinen U; Settimo L; Johnson MS; Pentikäinen OT
Org Biomol Chem; 2006 Mar; 4(6):1058-70. PubMed ID: 16525550
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]