These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

581 related articles for article (PubMed ID: 19738044)

  • 1. Inactivation of the Carney complex gene 1 (protein kinase A regulatory subunit 1A) inhibits SMAD3 expression and TGF beta-stimulated apoptosis in adrenocortical cells.
    Ragazzon B; Cazabat L; Rizk-Rabin M; Assie G; Groussin L; Fierrard H; Perlemoine K; Martinez A; Bertherat J
    Cancer Res; 2009 Sep; 69(18):7278-84. PubMed ID: 19738044
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and other PRKAR1A induced lesions.
    Griffin KJ; Kirschner LS; Matyakhina L; Stergiopoulos SG; Robinson-White A; Lenherr SM; Weinberg FD; Claflin ES; Batista D; Bourdeau I; Voutetakis A; Sandrini F; Meoli EM; Bauer AJ; Cho-Chung YS; Bornstein SR; Carney JA; Stratakis CA
    J Med Genet; 2004 Dec; 41(12):923-31. PubMed ID: 15591278
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular and functional analysis of PRKAR1A and its locus (17q22-24) in sporadic adrenocortical tumors: 17q losses, somatic mutations, and protein kinase A expression and activity.
    Bertherat J; Groussin L; Sandrini F; Matyakhina L; Bei T; Stergiopoulos S; Papageorgiou T; Bourdeau I; Kirschner LS; Vincent-Dejean C; Perlemoine K; Gicquel C; Bertagna X; Stratakis CA
    Cancer Res; 2003 Sep; 63(17):5308-19. PubMed ID: 14500362
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Depletion of type IA regulatory subunit (RIalpha) of protein kinase A (PKA) in mammalian cells and tissues activates mTOR and causes autophagic deficiency.
    Mavrakis M; Lippincott-Schwartz J; Stratakis CA; Bossis I
    Hum Mol Genet; 2006 Oct; 15(19):2962-71. PubMed ID: 16963469
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Use of mouse models to understand the molecular basis of tissue-specific tumorigenesis in the Carney complex.
    Kirschner LS
    J Intern Med; 2009 Jul; 266(1):60-8. PubMed ID: 19522826
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular cloning, chromosomal localization of human peripheral-type benzodiazepine receptor and PKA regulatory subunit type 1A (PRKAR1A)-associated protein PAP7, and studies in PRKAR1A mutant cells and tissues.
    Liu J; Matyakhina L; Han Z; Sandrini F; Bei T; Stratakis CA; Papadopoulos V
    FASEB J; 2003 Jun; 17(9):1189-91. PubMed ID: 12692076
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cyclic adenosine 3',5'-monophosphate-elevating agents inhibit transforming growth factor-beta-induced SMAD3/4-dependent transcription via a protein kinase A-dependent mechanism.
    Schiller M; Verrecchia F; Mauviel A
    Oncogene; 2003 Dec; 22(55):8881-90. PubMed ID: 14654784
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors.
    Griffin KJ; Kirschner LS; Matyakhina L; Stergiopoulos S; Robinson-White A; Lenherr S; Weinberg FD; Claflin E; Meoli E; Cho-Chung YS; Stratakis CA
    Cancer Res; 2004 Dec; 64(24):8811-5. PubMed ID: 15604237
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Disruption of protein kinase a regulation causes immortalization and dysregulation of D-type cyclins.
    Nadella KS; Kirschner LS
    Cancer Res; 2005 Nov; 65(22):10307-15. PubMed ID: 16288019
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutational analysis of PRKAR1A and Gs(alpha) in sporadic adrenocortical tumors.
    Libé R; Mantovani G; Bondioni S; Lania AG; Pedroni C; Beck-Peccoz P; Spada A
    Exp Clin Endocrinol Diabetes; 2005 May; 113(5):248-51. PubMed ID: 15926108
    [TBL] [Abstract][Full Text] [Related]  

  • 11. cAMP-dependent protein kinase activation inhibits proliferation and enhances apoptotic effect of tumor necrosis factor-alpha in NCI-H295R adrenocortical cells.
    Liu J; Li XD; Ora A; Heikkilä P; Vaheri A; Voutilainen R
    J Mol Endocrinol; 2004 Oct; 33(2):511-22. PubMed ID: 15525605
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulatory subunit type I-alpha of protein kinase A (PRKAR1A): a tumor-suppressor gene for sporadic thyroid cancer.
    Sandrini F; Matyakhina L; Sarlis NJ; Kirschner LS; Farmakidis C; Gimm O; Stratakis CA
    Genes Chromosomes Cancer; 2002 Oct; 35(2):182-92. PubMed ID: 12203783
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evidence that PKA activity is constitutively activated in human GH-secreting adenoma cells in a patient with Carney complex harbouring a PRKAR1A mutation.
    Takano K; Yasufuku-Takano J; Morita K; Mori S; Takei M; Osamura RY; Teramoto A; Fujita T
    Clin Endocrinol (Oxf); 2009 May; 70(5):769-75. PubMed ID: 19178533
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The tumor suppressor KLF11 mediates a novel mechanism in transforming growth factor beta-induced growth inhibition that is inactivated in pancreatic cancer.
    Buck A; Buchholz M; Wagner M; Adler G; Gress T; Ellenrieder V
    Mol Cancer Res; 2006 Nov; 4(11):861-72. PubMed ID: 17114344
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia.
    Bourdeau I; Matyakhina L; Stergiopoulos SG; Sandrini F; Boikos S; Stratakis CA
    J Clin Endocrinol Metab; 2006 Sep; 91(9):3626-32. PubMed ID: 16772351
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protein kinase A alterations in endocrine tumors.
    Yu B; Ragazzon B; Rizk-Rabin M; Bertherat J
    Horm Metab Res; 2012 Sep; 44(10):741-8. PubMed ID: 22752956
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PRKAR1A Mutations and protein kinase A interactions with other signaling pathways in the adrenal cortex.
    Robinson-White A; Meoli E; Stergiopoulos S; Horvath A; Boikos S; Bossis I; Stratakis CA
    J Clin Endocrinol Metab; 2006 Jun; 91(6):2380-8. PubMed ID: 16569736
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transcription of LIPE gene encoding hormone-sensitive lipase/cholesteryl esterase is regulated by SF-1 in human adrenocortical cells: involvement of protein kinase A signal transduction pathway.
    Hołlysz M; Derebecka-Hołysz N; Trzeciak WH
    J Mol Endocrinol; 2011 Feb; 46(1):29-36. PubMed ID: 21081692
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A mouse model for the Carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues.
    Kirschner LS; Kusewitt DF; Matyakhina L; Towns WH; Carney JA; Westphal H; Stratakis CA
    Cancer Res; 2005 Jun; 65(11):4506-14. PubMed ID: 15930266
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Compensatory stabilization of RIIbeta protein, cell cycle deregulation, and growth arrest in colon and prostate carcinoma cells by antisense-directed down-regulation of protein kinase A RIalpha protein.
    Nesterova M; Noguchi K; Park YG; Lee YN; Cho-Chung YS
    Clin Cancer Res; 2000 Sep; 6(9):3434-41. PubMed ID: 10999726
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.