BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 19738461)

  • 1. Cisplatin enhances the anticancer effect of beta-lapachone by upregulating NQO1.
    Terai K; Dong GZ; Oh ET; Park MT; Gu Y; Song CW; Park HJ
    Anticancer Drugs; 2009 Nov; 20(10):901-9. PubMed ID: 19738461
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Susceptibility of cancer cells to beta-lapachone is enhanced by ionizing radiation.
    Park HJ; Ahn KJ; Ahn SD; Choi E; Lee SW; Williams B; Kim EJ; Griffin R; Bey EA; Bornmann WG; Gao J; Park HJ; Boothman DA; Song CW
    Int J Radiat Oncol Biol Phys; 2005 Jan; 61(1):212-9. PubMed ID: 15629614
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Anti-cancer effect of bio-reductive drug beta-lapachon is enhanced by activating NQO1 with heat shock.
    Song CW; Chae JJ; Choi EK; Hwang TS; Kim C; Lim BU; Park HJ
    Int J Hyperthermia; 2008 Mar; 24(2):161-9. PubMed ID: 18283592
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heat-induced up-regulation of NAD(P)H:quinone oxidoreductase potentiates anticancer effects of beta-lapachone.
    Park HJ; Choi EK; Choi J; Ahn KJ; Kim EJ; Ji IM; Kook YH; Ahn SD; Williams B; Griffin R; Boothman DA; Lee CK; Song CW
    Clin Cancer Res; 2005 Dec; 11(24 Pt 1):8866-71. PubMed ID: 16361576
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Upregulation of NAD(P)H:quinone oxidoreductase by radiation potentiates the effect of bioreductive beta-lapachone on cancer cells.
    Choi EK; Terai K; Ji IM; Kook YH; Park KH; Oh ET; Griffin RJ; Lim BU; Kim JS; Lee DS; Boothman DA; Loren M; Song CW; Park HJ
    Neoplasia; 2007 Aug; 9(8):634-42. PubMed ID: 17786182
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Heat shock increases expression of NAD(P)H:quinone oxidoreductase (NQO1), mediator of beta-lapachone cytotoxicity, by increasing NQO1 gene activity and via Hsp70-mediated stabilisation of NQO1 protein.
    Dong GZ; Youn H; Park MT; Oh ET; Park KH; Song CW; Choi EK; Park HJ
    Int J Hyperthermia; 2009; 25(6):477-87. PubMed ID: 19657853
    [TBL] [Abstract][Full Text] [Related]  

  • 7. β-Lapachone Induces NAD(P)H:Quinone Oxidoreductase-1- and Oxidative Stress-Dependent Heat Shock Protein 90 Cleavage and Inhibits Tumor Growth and Angiogenesis.
    Wu Y; Wang X; Chang S; Lu W; Liu M; Pang X
    J Pharmacol Exp Ther; 2016 Jun; 357(3):466-75. PubMed ID: 27048660
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hyperthermia enhances the effect of β-lapachone to cause γH2AX formations and cell death in human osteosarcoma cells.
    Hori T; Kondo T; Lee H; Song CW; Park HJ
    Int J Hyperthermia; 2011; 27(1):53-62. PubMed ID: 21070139
    [TBL] [Abstract][Full Text] [Related]  

  • 9. β-Lapachone promotes the recruitment and polarization of tumor-associated neutrophils (TANs) toward an antitumor (N1) phenotype in NQO1-positive cancers.
    Tumbath S; Jiang L; Li X; Zhang T; Zahid KR; Zhao Y; Zhou H; Yin Z; Lu T; Jiang S; Chen Y; Chen X; Fu YX; Huang X
    Oncoimmunology; 2024; 13(1):2363000. PubMed ID: 38846085
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mitochondrial activity is the key to the protective effect of β-Lapachone, a NAD
    Lin SY; Syu JP; Lo YT; Chau YP; Don MJ; Shy HT; Lai SM; Kung HN
    Phytomedicine; 2022 Jul; 101():154094. PubMed ID: 35447421
    [TBL] [Abstract][Full Text] [Related]  

  • 11. beta-Lapachone-induced apoptosis in human prostate cancer cells: involvement of NQO1/xip3.
    Planchon SM; Pink JJ; Tagliarino C; Bornmann WG; Varnes ME; Boothman DA
    Exp Cell Res; 2001 Jul; 267(1):95-106. PubMed ID: 11412042
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone.
    Moore Z; Chakrabarti G; Luo X; Ali A; Hu Z; Fattah FJ; Vemireddy R; DeBerardinis RJ; Brekken RA; Boothman DA
    Cell Death Dis; 2015 Jan; 6(1):e1599. PubMed ID: 25590809
    [TBL] [Abstract][Full Text] [Related]  

  • 13. β-lapachone significantly increases the effect of ionizing radiation to cause mitochondrial apoptosis via JNK activation in cancer cells.
    Park MT; Song MJ; Lee H; Oh ET; Choi BH; Jeong SY; Choi EK; Park HJ
    PLoS One; 2011; 6(10):e25976. PubMed ID: 21998736
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tumor-selective, futile redox cycle-induced bystander effects elicited by NQO1 bioactivatable radiosensitizing drugs in triple-negative breast cancers.
    Cao L; Li LS; Spruell C; Xiao L; Chakrabarti G; Bey EA; Reinicke KE; Srougi MC; Moore Z; Dong Y; Vo P; Kabbani W; Yang CR; Wang X; Fattah F; Morales JC; Motea EA; Bornmann WG; Yordy JS; Boothman DA
    Antioxid Redox Signal; 2014 Jul; 21(2):237-50. PubMed ID: 24512128
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Endoplasmic reticulum stress-induced JNK activation is a critical event leading to mitochondria-mediated cell death caused by β-lapachone treatment.
    Lee H; Park MT; Choi BH; Oh ET; Song MJ; Lee J; Kim C; Lim BU; Park HJ
    PLoS One; 2011; 6(6):e21533. PubMed ID: 21738692
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synergistic enhancement of antitumor effect of β-Lapachone by photodynamic induction of quinone oxidoreductase (NQO1).
    Lamberti MJ; Vittar NB; da Silva Fde C; Ferreira VF; Rivarola VA
    Phytomedicine; 2013 Aug; 20(11):1007-12. PubMed ID: 23746950
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sulindac compounds facilitate the cytotoxicity of β-lapachone by up-regulation of NAD(P)H quinone oxidoreductase in human lung cancer cells.
    Kung HN; Weng TY; Liu YL; Lu KS; Chau YP
    PLoS One; 2014; 9(2):e88122. PubMed ID: 24505400
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Modulating endogenous NQO1 levels identifies key regulatory mechanisms of action of β-lapachone for pancreatic cancer therapy.
    Li LS; Bey EA; Dong Y; Meng J; Patra B; Yan J; Xie XJ; Brekken RA; Barnett CC; Bornmann WG; Gao J; Boothman DA
    Clin Cancer Res; 2011 Jan; 17(2):275-85. PubMed ID: 21224367
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Beta-lapachone-containing PEG-PLA polymer micelles as novel nanotherapeutics against NQO1-overexpressing tumor cells.
    Blanco E; Bey EA; Dong Y; Weinberg BD; Sutton DM; Boothman DA; Gao J
    J Control Release; 2007 Oct; 122(3):365-74. PubMed ID: 17574288
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhancement of radiation effect using beta-lapachone and underlying mechanism.
    Ahn KJ; Lee HS; Bai SK; Song CW
    Radiat Oncol J; 2013 Jun; 31(2):57-65. PubMed ID: 23865001
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.