BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 19739101)

  • 1. Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbfbeta in osteosarcoma cells.
    San Martin IA; Varela N; Gaete M; Villegas K; Osorio M; Tapia JC; Antonelli M; Mancilla EE; Pereira BP; Nathan SS; Lian JB; Stein JL; Stein GS; van Wijnen AJ; Galindo M
    J Cell Physiol; 2009 Dec; 221(3):560-71. PubMed ID: 19739101
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts.
    Galindo M; Pratap J; Young DW; Hovhannisyan H; Im HJ; Choi JY; Lian JB; Stein JL; Stein GS; van Wijnen AJ
    J Biol Chem; 2005 May; 280(21):20274-85. PubMed ID: 15781466
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metastatic breast cancer cells inhibit osteoblast differentiation through the Runx2/CBFβ-dependent expression of the Wnt antagonist, sclerostin.
    Mendoza-Villanueva D; Zeef L; Shore P
    Breast Cancer Res; 2011 Oct; 13(5):R106. PubMed ID: 22032690
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cell cycle related modulations in Runx2 protein levels are independent of lymphocyte enhancer-binding factor 1 (Lef1) in proliferating osteoblasts.
    Galindo M; Kahler RA; Teplyuk NM; Stein JL; Lian JB; Stein GS; Westendorf JJ; van Wijnen AJ
    J Mol Histol; 2007 Oct; 38(5):501-6. PubMed ID: 17885813
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).
    Pereira BP; Zhou Y; Gupta A; Leong DT; Aung KZ; Ling L; Pho RW; Galindo M; Salto-Tellez M; Stein GS; Cool SM; van Wijnen AJ; Nathan SS
    J Cell Physiol; 2009 Dec; 221(3):778-88. PubMed ID: 19746444
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The cancer-related transcription factor Runx2 modulates cell proliferation in human osteosarcoma cell lines.
    Lucero CM; Vega OA; Osorio MM; Tapia JC; Antonelli M; Stein GS; van Wijnen AJ; Galindo MA
    J Cell Physiol; 2013 Apr; 228(4):714-23. PubMed ID: 22949168
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cbfβ deletion in mice recapitulates cleidocranial dysplasia and reveals multiple functions of Cbfβ required for skeletal development.
    Chen W; Ma J; Zhu G; Jules J; Wu M; McConnell M; Tian F; Paulson C; Zhou X; Wang L; Li YP
    Proc Natl Acad Sci U S A; 2014 Jun; 111(23):8482-7. PubMed ID: 24850862
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cbfβ governs osteoblast-adipocyte lineage commitment through enhancing β-catenin signaling and suppressing adipogenesis gene expression.
    Wu M; Wang Y; Shao JZ; Wang J; Chen W; Li YP
    Proc Natl Acad Sci U S A; 2017 Sep; 114(38):10119-10124. PubMed ID: 28864530
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma.
    Thomas DM; Johnson SA; Sims NA; Trivett MK; Slavin JL; Rubin BP; Waring P; McArthur GA; Walkley CR; Holloway AJ; Diyagama D; Grim JE; Clurman BE; Bowtell DD; Lee JS; Gutierrez GM; Piscopo DM; Carty SA; Hinds PW
    J Cell Biol; 2004 Dec; 167(5):925-34. PubMed ID: 15583032
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Core binding factor β of osteoblasts maintains cortical bone mass via stabilization of Runx2 in mice.
    Lim KE; Park NR; Che X; Han MS; Jeong JH; Kim SY; Park CY; Akiyama H; Kim JE; Ryoo HM; Stein JL; Lian JB; Stein GS; Choi JY
    J Bone Miner Res; 2015 Apr; 30(4):715-22. PubMed ID: 25358268
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitotic control of RUNX2 phosphorylation by both CDK1/cyclin B kinase and PP1/PP2A phosphatase in osteoblastic cells.
    Rajgopal A; Young DW; Mujeeb KA; Stein JL; Lian JB; van Wijnen AJ; Stein GS
    J Cell Biochem; 2007 Apr; 100(6):1509-17. PubMed ID: 17171635
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The interaction between RUNX2 and core binding factor beta as a potential therapeutic target in canine osteosarcoma.
    Alegre F; Ormonde AR; Godinez DR; Illendula A; Bushweller JH; Wittenburg LA
    Vet Comp Oncol; 2020 Mar; 18(1):52-63. PubMed ID: 31381810
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma.
    van der Deen M; Taipaleenmäki H; Zhang Y; Teplyuk NM; Gupta A; Cinghu S; Shogren K; Maran A; Yaszemski MJ; Ling L; Cool SM; Leong DT; Dierkes C; Zustin J; Salto-Tellez M; Ito Y; Bae SC; Zielenska M; Squire JA; Lian JB; Stein JL; Zambetti GP; Jones SN; Galindo M; Hesse E; Stein GS; van Wijnen AJ
    J Biol Chem; 2013 Jul; 288(29):21307-21319. PubMed ID: 23720736
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma.
    Nathan SS; Pereira BP; Zhou YF; Gupta A; Dombrowski C; Soong R; Pho RW; Stein GS; Salto-Tellez M; Cool SM; van Wijnen AJ
    Mol Biol Rep; 2009 Jan; 36(1):153-8. PubMed ID: 18931939
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation.
    Qiao M; Shapiro P; Fosbrink M; Rus H; Kumar R; Passaniti A
    J Biol Chem; 2006 Mar; 281(11):7118-28. PubMed ID: 16407259
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression of the ectodomain-releasing protease ADAM17 is directly regulated by the osteosarcoma and bone-related transcription factor RUNX2.
    Araya HF; Sepulveda H; Lizama CO; Vega OA; Jerez S; Briceño PF; Thaler R; Riester SM; Antonelli M; Salazar-Onfray F; Rodríguez JP; Moreno RD; Montecino M; Charbonneau M; Dubois CM; Stein GS; van Wijnen AJ; Galindo MA
    J Cell Biochem; 2018 Nov; 119(10):8204-8219. PubMed ID: 29923217
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The cancer-related transcription factor RUNX2 modulates expression and secretion of the matricellular protein osteopontin in osteosarcoma cells to promote adhesion to endothelial pulmonary cells and lung metastasis.
    Villanueva F; Araya H; Briceño P; Varela N; Stevenson A; Jerez S; Tempio F; Chnaiderman J; Perez C; Villarroel M; Concha E; Khani F; Thaler R; Salazar-Onfray F; Stein GS; van Wijnen AJ; Galindo M
    J Cell Physiol; 2019 Aug; 234(8):13659-13679. PubMed ID: 30637720
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mitotic Inheritance of mRNA Facilitates Translational Activation of the Osteogenic-Lineage Commitment Factor Runx2 in Progeny of Osteoblastic Cells.
    Varela N; Aranguiz A; Lizama C; Sepulveda H; Antonelli M; Thaler R; Moreno RD; Montecino M; Stein GS; van Wijnen AJ; Galindo M
    J Cell Physiol; 2016 May; 231(5):1001-14. PubMed ID: 26381402
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hypoxia-inducible factor 2α is a novel inhibitor of chondrocyte maturation.
    Che X; Park NR; Jin X; Jung YK; Han MS; Park CY; Chun JS; Kim SG; Jin J; Kim HJ; Lian JB; Stein JL; Stein GS; Choi JY
    J Cell Physiol; 2021 Oct; 236(10):6963-6973. PubMed ID: 33748969
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Menin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2.
    Sowa H; Kaji H; Hendy GN; Canaff L; Komori T; Sugimoto T; Chihara K
    J Biol Chem; 2004 Sep; 279(39):40267-75. PubMed ID: 15150273
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.