87 related articles for article (PubMed ID: 19740108)
1. Completing the hypusine pathway in Plasmodium.
Frommholz D; Kusch P; Blavid R; Scheer H; Tu JM; Marcus K; Zhao KH; Atemnkeng V; Marciniak J; Kaiser AE
FEBS J; 2009 Oct; 276(20):5881-91. PubMed ID: 19740108
[TBL] [Abstract][Full Text] [Related]
2. Assessment of deoxyhypusine hydroxylase as a putative, novel drug target.
Kerscher B; Nzukou E; Kaiser A
Amino Acids; 2010 Feb; 38(2):471-7. PubMed ID: 19956997
[TBL] [Abstract][Full Text] [Related]
3. Deoxyhypusine hydroxylase from Plasmodium vivax, the neglected human malaria parasite: molecular cloning, expression and specific inhibition by the 5-LOX inhibitor zileuton.
Atemnkeng VA; Pink M; Schmitz-Spanke S; Wu XJ; Dong LL; Zhao KH; May C; Laufer S; Langer B; Kaiser A
PLoS One; 2013; 8(3):e58318. PubMed ID: 23505486
[TBL] [Abstract][Full Text] [Related]
4. A unique modification of the eukaryotic initiation factor 5A shows the presence of the complete hypusine pathway in Leishmania donovani.
Chawla B; Kumar RR; Tyagi N; Subramanian G; Srinivasan N; Park MH; Madhubala R
PLoS One; 2012; 7(3):e33138. PubMed ID: 22438895
[TBL] [Abstract][Full Text] [Related]
5. Molecular cloning, expression, and structural prediction of deoxyhypusine hydroxylase: a HEAT-repeat-containing metalloenzyme.
Park JH; Aravind L; Wolff EC; Kaevel J; Kim YS; Park MH
Proc Natl Acad Sci U S A; 2006 Jan; 103(1):51-6. PubMed ID: 16371467
[TBL] [Abstract][Full Text] [Related]
6. A rapid and robust assay for the determination of the amino acid hypusine as a possible biomarker for a high-throughput screening of antimalarials and for the diagnosis and therapy of different diseases.
Kaiser A; Khomutov AR; Simonian A; Agostinelli E
Amino Acids; 2012 May; 42(5):1651-9. PubMed ID: 21360085
[TBL] [Abstract][Full Text] [Related]
7. New insights into novel inhibitors against deoxyhypusine hydroxylase from plasmodium falciparum: compounds with an iron chelating potential.
von Koschitzky I; Gerhardt H; Lämmerhofer M; Kohout M; Gehringer M; Laufer S; Pink M; Schmitz-Spanke S; Strube C; Kaiser A
Amino Acids; 2015 Jun; 47(6):1155-66. PubMed ID: 25715757
[TBL] [Abstract][Full Text] [Related]
8. Hypusine: its post-translational formation in eukaryotic initiation factor 5A and its potential role in cellular regulation.
Park MH; Wolff EC; Folk JE
Biofactors; 1993 May; 4(2):95-104. PubMed ID: 8347280
[TBL] [Abstract][Full Text] [Related]
9. Cloning, expression and functional activity of deoxyhypusine synthase from Plasmodium vivax.
Njuguna JT; Nassar M; Hoerauf A; Kaiser AE
BMC Microbiol; 2006 Oct; 6():91. PubMed ID: 17042947
[TBL] [Abstract][Full Text] [Related]
10. Translation initiation factor eIF-5A from Plasmodium falciparum.
Molitor IM; Knöbel S; Dang C; Spielmann T; Alléra A; König GM
Mol Biochem Parasitol; 2004 Sep; 137(1):65-74. PubMed ID: 15279952
[TBL] [Abstract][Full Text] [Related]
11. Crystal Structure of the Peroxo-diiron(III) Intermediate of Deoxyhypusine Hydroxylase, an Oxygenase Involved in Hypusination.
Han Z; Sakai N; Böttger LH; Klinke S; Hauber J; Trautwein AX; Hilgenfeld R
Structure; 2015 May; 23(5):882-892. PubMed ID: 25865244
[TBL] [Abstract][Full Text] [Related]
12. Specificity of the deoxyhypusine hydroxylase-eukaryotic translation initiation factor (eIF5A) interaction: identification of amino acid residues of the enzyme required for binding of its substrate, deoxyhypusine-containing eIF5A.
Kang KR; Kim YS; Wolff EC; Park MH
J Biol Chem; 2007 Mar; 282(11):8300-8. PubMed ID: 17213197
[TBL] [Abstract][Full Text] [Related]
13. Chemical profiling of deoxyhypusine hydroxylase inhibitors for antimalarial therapy.
von Koschitzky I; Kaiser A
Amino Acids; 2013 Nov; 45(5):1047-53. PubMed ID: 23943044
[TBL] [Abstract][Full Text] [Related]
14. Modification of eukaryotic initiation factor 5A from Plasmodium vivax by a truncated deoxyhypusine synthase from Plasmodium falciparum: An enzyme with dual enzymatic properties.
Kaiser A; Hammels I; Gottwald A; Nassar M; Zaghloul MS; Motaal BA; Hauber J; Hoerauf A
Bioorg Med Chem; 2007 Sep; 15(18):6200-7. PubMed ID: 17591443
[TBL] [Abstract][Full Text] [Related]
15. A suggested vital function for eIF-5A and dhs genes during murine malaria blood-stage infection.
Kersting D; Krüger M; Sattler JM; Mueller AK; Kaiser A
FEBS Open Bio; 2016 Aug; 6(8):860-72. PubMed ID: 27516964
[TBL] [Abstract][Full Text] [Related]
16. Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.
Preukschas M; Hagel C; Schulte A; Weber K; Lamszus K; Sievert H; Pällmann N; Bokemeyer C; Hauber J; Braig M; Balabanov S
PLoS One; 2012; 7(8):e43468. PubMed ID: 22927971
[TBL] [Abstract][Full Text] [Related]
17. Bi-allelic variants in DOHH, catalyzing the last step of hypusine biosynthesis, are associated with a neurodevelopmental disorder.
Ziegler A; Steindl K; Hanner AS; Kar RK; Prouteau C; Boland A; Deleuze JF; Coubes C; Bézieau S; Küry S; Maystadt I; Le Mao M; Lenaers G; Navet B; Faivre L; Tran Mau-Them F; Zanoni P; Chung WK; Rauch A; Bonneau D; Park MH
Am J Hum Genet; 2022 Aug; 109(8):1549-1558. PubMed ID: 35858628
[TBL] [Abstract][Full Text] [Related]
18. Biological Relevance and Therapeutic Potential of the Hypusine Modification System.
Pällmann N; Braig M; Sievert H; Preukschas M; Hermans-Borgmeyer I; Schweizer M; Nagel CH; Neumann M; Wild P; Haralambieva E; Hagel C; Bokemeyer C; Hauber J; Balabanov S
J Biol Chem; 2015 Jul; 290(30):18343-60. PubMed ID: 26037925
[TBL] [Abstract][Full Text] [Related]
19. In vitro and in vivo silencing of plasmodial dhs and eIf-5a genes in a putative, non-canonical RNAi-related pathway.
Schwentke A; Krepstakies M; Mueller AK; Hammerschmidt-Kamper C; Motaal BA; Bernhard T; Hauber J; Kaiser A
BMC Microbiol; 2012 Jun; 12():107. PubMed ID: 22694849
[TBL] [Abstract][Full Text] [Related]
20. The Beauty of a Visualized Peroxo-diiron(III) Intermediate.
Grüber G
Structure; 2015 May; 23(5):805-806. PubMed ID: 25955100
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]