155 related articles for article (PubMed ID: 19740394)
1. Intracellular 'boosting' of darunavir using known transport inhibitors in primary PBMC.
Kwan WS; Janneh O; Hartkoorn R; Chandler B; Khoo S; Back D; Owen A
Br J Clin Pharmacol; 2009 Sep; 68(3):375-80. PubMed ID: 19740394
[TBL] [Abstract][Full Text] [Related]
2. P-glycoprotein, multidrug resistance-associated proteins and human organic anion transporting polypeptide influence the intracellular accumulation of atazanavir.
Janneh O; Anwar T; Jungbauer C; Kopp S; Khoo SH; Back DJ; Chiba P
Antivir Ther; 2009; 14(7):965-74. PubMed ID: 19918100
[TBL] [Abstract][Full Text] [Related]
3. Differences in the intracellular accumulation of HIV protease inhibitors in vitro and the effect of active transport.
Jones K; Hoggard PG; Sales SD; Khoo S; Davey R; Back DJ
AIDS; 2001 Apr; 15(6):675-81. PubMed ID: 11371681
[TBL] [Abstract][Full Text] [Related]
4. P-glycoprotein mediates efflux transport of darunavir in human intestinal Caco-2 and ABCB1 gene-transfected renal LLC-PK1 cell lines.
Fujimoto H; Higuchi M; Watanabe H; Koh Y; Ghosh AK; Mitsuya H; Tanoue N; Hamada A; Saito H
Biol Pharm Bull; 2009 Sep; 32(9):1588-93. PubMed ID: 19721237
[TBL] [Abstract][Full Text] [Related]
5. Intracellular accumulation of ritonavir combined with different protease inhibitors and correlations between concentrations in plasma and peripheral blood mononuclear cells.
D'Avolio A; Simiele M; Calcagno A; Siccardi M; Larovere G; Agati S; Baietto L; Cusato J; Tettoni M; Sciandra M; Trentini L; Di Perri G; Bonora S
J Antimicrob Chemother; 2013 Apr; 68(4):907-10. PubMed ID: 23221630
[TBL] [Abstract][Full Text] [Related]
6. Darunavir concentration in PBMCs may be a better indicator of drug exposure in HIV patients.
Nagano D; Araki T; Yanagisawa K; Ogawa Y; Gohda F; Uchiumi H; Handa H; Nakamura T; Yamamoto K
Eur J Clin Pharmacol; 2018 Aug; 74(8):1055-1060. PubMed ID: 29721582
[TBL] [Abstract][Full Text] [Related]
7. Concentration-dependent effects and intracellular accumulation of HIV protease inhibitors in cultured CD4 T cells and primary human lymphocytes.
Janneh O; Bray PG; Jones E; Wyen C; Chiba P; Back DJ; Khoo SH
J Antimicrob Chemother; 2010 May; 65(5):906-16. PubMed ID: 20237075
[TBL] [Abstract][Full Text] [Related]
8. Intracellular accumulation of efavirenz and nevirapine is independent of P-glycoprotein activity in cultured CD4 T cells and primary human lymphocytes.
Janneh O; Chandler B; Hartkoorn R; Kwan WS; Jenkinson C; Evans S; Back DJ; Owen A; Khoo SH
J Antimicrob Chemother; 2009 Nov; 64(5):1002-7. PubMed ID: 19748977
[TBL] [Abstract][Full Text] [Related]
9. Placental transfer of darunavir in an ex vivo human cotyledon perfusion model.
Mandelbrot L; Duro D; Belissa E; Peytavin G
Antimicrob Agents Chemother; 2014 Sep; 58(9):5617-20. PubMed ID: 24982090
[TBL] [Abstract][Full Text] [Related]
10. Darunavir/ritonavir and efavirenz exert differential effects on MRP1 transporter expression and function in healthy volunteers.
Lee LS; Soon GH; Shen P; Yong EL; Flexner C; Pham P
Antivir Ther; 2010; 15(2):275-9. PubMed ID: 20386083
[TBL] [Abstract][Full Text] [Related]
11. P-Glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: potential for accelerated viral drug resistance?
Jones K; Bray PG; Khoo SH; Davey RA; Meaden ER; Ward SA; Back DJ
AIDS; 2001 Jul; 15(11):1353-8. PubMed ID: 11504956
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of P-glycoprotein and multidrug resistance-associated proteins modulates the intracellular concentration of lopinavir in cultured CD4 T cells and primary human lymphocytes.
Janneh O; Jones E; Chandler B; Owen A; Khoo SH
J Antimicrob Chemother; 2007 Nov; 60(5):987-93. PubMed ID: 17890284
[TBL] [Abstract][Full Text] [Related]
13. HIV protease inhibitors: garlic supplements and first-pass intestinal metabolism impact on the therapeutic efficacy.
Berginc K; Trdan T; Trontelj J; Kristl A
Biopharm Drug Dispos; 2010 Nov; 31(8-9):495-505. PubMed ID: 21104925
[TBL] [Abstract][Full Text] [Related]
14. Cultured CD4T cells and primary human lymphocytes express hOATPs: intracellular accumulation of saquinavir and lopinavir.
Janneh O; Hartkoorn RC; Jones E; Owen A; Ward SA; Davey R; Back DJ; Khoo SH
Br J Pharmacol; 2008 Nov; 155(6):875-83. PubMed ID: 19002102
[TBL] [Abstract][Full Text] [Related]
15. Determinants of darunavir cerebrospinal fluid concentrations: impact of once-daily dosing and pharmacogenetics.
Calcagno A; Yilmaz A; Cusato J; Simiele M; Bertucci R; Siccardi M; Marinaro L; D'Avolio A; Di Perri G; Bonora S
AIDS; 2012 Jul; 26(12):1529-33. PubMed ID: 22555164
[TBL] [Abstract][Full Text] [Related]
16. Species-specific interaction of HIV protease inhibitors with accumulation of cholyl-glycylamido-fluorescein (CGamF) in sandwich-cultured hepatocytes.
Ye ZW; Van Pelt J; Camus S; Snoeys J; Augustijns P; Annaert P
J Pharm Sci; 2010 Jun; 99(6):2886-98. PubMed ID: 20014428
[TBL] [Abstract][Full Text] [Related]
17. Solution kinetics measurements suggest HIV-1 protease has two binding sites for darunavir and amprenavir.
Kovalevsky AY; Ghosh AK; Weber IT
J Med Chem; 2008 Oct; 51(20):6599-603. PubMed ID: 18808097
[TBL] [Abstract][Full Text] [Related]
18. Determination of P-glycoprotein surface expression and functional ability after in vitro treatment with darunavir or raltegravir in lymphocytes of healthy donors.
Tempestilli M; Gentilotti E; Tommasi C; Nicastri E; Martini F; De Nardo P; Narciso P; Pucillo LP
Int Immunopharmacol; 2013 Aug; 16(4):492-7. PubMed ID: 23707228
[TBL] [Abstract][Full Text] [Related]
19. Darunavir: a review of its use in the management of HIV infection in adults.
McKeage K; Perry CM; Keam SJ
Drugs; 2009; 69(4):477-503. PubMed ID: 19323590
[TBL] [Abstract][Full Text] [Related]
20. Quantification of darunavir and etravirine in human peripheral blood mononuclear cells using high performance liquid chromatography tandem mass spectrometry (LC-MS/MS), clinical application in a cohort of 110 HIV-1 infected patients and evidence of a potential drug-drug interaction.
Belkhir L; De Laveleye M; Vandercam B; Zech F; Delongie KA; Capron A; Yombi J; Vincent A; Elens L; Haufroid V
Clin Biochem; 2016 May; 49(7-8):580-6. PubMed ID: 26742721
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
