207 related articles for article (PubMed ID: 19741165)
1. Transgenically induced GAD tolerance curtails the development of early beta-cell autoreactivities but causes the subsequent development of supernormal autoreactivities to other beta-cell antigens.
Tian J; Dang H; von Boehmer H; Jaeckel E; Kaufman DL
Diabetes; 2009 Dec; 58(12):2843-50. PubMed ID: 19741165
[TBL] [Abstract][Full Text] [Related]
2. Glutamic acid decarboxylase T lymphocyte responses associated with susceptibility or resistance to type I diabetes: analysis in disease discordant human twins, non-obese diabetic mice and HLA-DQ transgenic mice.
Boyton RJ; Lohmann T; Londei M; Kalbacher H; Halder T; Frater AJ; Douek DC; Leslie DG; Flavell RA; Altmann DM
Int Immunol; 1998 Dec; 10(12):1765-76. PubMed ID: 9885897
[TBL] [Abstract][Full Text] [Related]
3. Widespread expression of an autoantigen-GAD65 transgene does not tolerize non-obese diabetic mice and can exacerbate disease.
Geng L; Solimena M; Flavell RA; Sherwin RS; Hayday AC
Proc Natl Acad Sci U S A; 1998 Aug; 95(17):10055-60. PubMed ID: 9707599
[TBL] [Abstract][Full Text] [Related]
4. Major DQ8-restricted T-cell epitopes for human GAD65 mapped using human CD4, DQA1*0301, DQB1*0302 transgenic IA(null) NOD mice.
Liu J; Purdy LE; Rabinovitch S; Jevnikar AM; Elliott JF
Diabetes; 1999 Mar; 48(3):469-77. PubMed ID: 10078545
[TBL] [Abstract][Full Text] [Related]
5. Prevention of autoimmune diabetes by immunogene therapy using recombinant vaccinia virus expressing glutamic acid decarboxylase.
Jun HS; Chung YH; Han J; Kim A; Yoo SS; Sherwin RS; Yoon JW
Diabetologia; 2002 May; 45(5):668-76. PubMed ID: 12107747
[TBL] [Abstract][Full Text] [Related]
6. Antigen-based immunotherapy drives the precocious development of autoimmunity.
Tian J; Olcott AP; Kaufman DL
J Immunol; 2002 Dec; 169(11):6564-9. PubMed ID: 12444168
[TBL] [Abstract][Full Text] [Related]
7. GAD-reactive CD4+ Th1 cells induce diabetes in NOD/SCID mice.
Zekzer D; Wong FS; Ayalon O; Millet I; Altieri M; Shintani S; Solimena M; Sherwin RS
J Clin Invest; 1998 Jan; 101(1):68-73. PubMed ID: 9421467
[TBL] [Abstract][Full Text] [Related]
8. T cells with multiple fine specificities are used by non-obese diabetic (NOD) mice in the response to GAD(524-543).
Quinn A; Sercarz EE
J Autoimmun; 1996 Jun; 9(3):365-70. PubMed ID: 8816972
[TBL] [Abstract][Full Text] [Related]
9. Homing of GAD65 specific autoimmunity and development of insulitis requires expression of both DQ8 and human GAD65 in transgenic mice.
Elagin RB; Balijepalli S; Diacovo MJ; Baekkeskov S; Jaume JC
J Autoimmun; 2009 Aug; 33(1):50-7. PubMed ID: 19289270
[TBL] [Abstract][Full Text] [Related]
10. Pathogenesis of NOD diabetes is initiated by reactivity to the insulin B chain 9-23 epitope and involves functional epitope spreading.
Prasad S; Kohm AP; McMahon JS; Luo X; Miller SD
J Autoimmun; 2012 Dec; 39(4):347-53. PubMed ID: 22647732
[TBL] [Abstract][Full Text] [Related]
11. Control of autoimmune diabetes in NOD mice by GAD expression or suppression in beta cells.
Yoon JW; Yoon CS; Lim HW; Huang QQ; Kang Y; Pyun KH; Hirasawa K; Sherwin RS; Jun HS
Science; 1999 May; 284(5417):1183-7. PubMed ID: 10325232
[TBL] [Abstract][Full Text] [Related]
12. Responses of NOD congenic mice to a glutamic acid decarboxylase-derived peptide.
Chen SL; Whiteley PJ; Freed DC; Rothbard JB; Peterson LB; Wicker LS
J Autoimmun; 1994 Oct; 7(5):635-41. PubMed ID: 7840855
[TBL] [Abstract][Full Text] [Related]
13. Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cells.
Kim SK; Tarbell KV; Sanna M; Vadeboncoeur M; Warganich T; Lee M; Davis M; McDevitt HO
Proc Natl Acad Sci U S A; 2004 Sep; 101(39):14204-9. PubMed ID: 15381770
[TBL] [Abstract][Full Text] [Related]
14. Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes.
Tian J; Atkinson MA; Clare-Salzler M; Herschenfeld A; Forsthuber T; Lehmann PV; Kaufman DL
J Exp Med; 1996 Apr; 183(4):1561-7. PubMed ID: 8666914
[TBL] [Abstract][Full Text] [Related]
15. 1alpha,25-dihydroxyvitamin D3 induces an autoantigen-specific T-helper 1/T-helper 2 immune shift in NOD mice immunized with GAD65 (p524-543).
Overbergh L; Decallonne B; Waer M; Rutgeerts O; Valckx D; Casteels KM; Laureys J; Bouillon R; Mathieu C
Diabetes; 2000 Aug; 49(8):1301-7. PubMed ID: 10923629
[TBL] [Abstract][Full Text] [Related]
16. Differential protection in two transgenic lines of NOD/Lt mice hyperexpressing the autoantigen GAD65 in pancreatic beta-cells.
Bridgett M; Cetkovic-Cvrlje M; O'Rourke R; Shi Y; Narayanswami S; Lambert J; Ramiya V; Baekkeskov S; Leiter EH
Diabetes; 1998 Dec; 47(12):1848-56. PubMed ID: 9836515
[TBL] [Abstract][Full Text] [Related]
17. Immunization with the larger isoform of mouse glutamic acid decarboxylase (GAD67) prevents autoimmune diabetes in NOD mice.
Elliott JF; Qin HY; Bhatti S; Smith DK; Singh RK; Dillon T; Lauzon J; Singh B
Diabetes; 1994 Dec; 43(12):1494-9. PubMed ID: 7525393
[TBL] [Abstract][Full Text] [Related]
18. Regulatory and effector CD4 T cells in nonobese diabetic mice recognize overlapping determinants on glutamic acid decarboxylase and use distinct V beta genes.
Quinn A; McInerney B; Reich EP; Kim O; Jensen KP; Sercarz EE
J Immunol; 2001 Mar; 166(5):2982-91. PubMed ID: 11207247
[TBL] [Abstract][Full Text] [Related]
19. GAD65 is recognized by T-cells, but not by antibodies from NOD-mice.
Bieg S; Seissler J; Herberg L; Northemann W; Scherbaum WA
Autoimmunity; 1994; 17(3):189-94. PubMed ID: 7948603
[TBL] [Abstract][Full Text] [Related]
20. Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.
Tisch R; Yang XD; Singer SM; Liblau RS; Fugger L; McDevitt HO
Nature; 1993 Nov; 366(6450):72-5. PubMed ID: 8232539
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]