BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

211 related articles for article (PubMed ID: 19744957)

  • 1. AIRE activated tissue specific genes have histone modifications associated with inactive chromatin.
    Org T; Rebane A; Kisand K; Laan M; Haljasorg U; Andreson R; Peterson P
    Hum Mol Genet; 2009 Dec; 18(24):4699-710. PubMed ID: 19744957
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA breaks and chromatin structural changes enhance the transcription of autoimmune regulator target genes.
    Guha M; Saare M; Maslovskaja J; Kisand K; Liiv I; Haljasorg U; Tasa T; Metspalu A; Milani L; Peterson P
    J Biol Chem; 2017 Apr; 292(16):6542-6554. PubMed ID: 28242760
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Unmodified histone H3K4 and DNA-dependent protein kinase recruit autoimmune regulator to target genes.
    Žumer K; Low AK; Jiang H; Saksela K; Peterlin BM
    Mol Cell Biol; 2012 Apr; 32(8):1354-62. PubMed ID: 22310661
    [TBL] [Abstract][Full Text] [Related]  

  • 4. AIRE recruits P-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells.
    Oven I; Brdicková N; Kohoutek J; Vaupotic T; Narat M; Peterlin BM
    Mol Cell Biol; 2007 Dec; 27(24):8815-23. PubMed ID: 17938200
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression.
    Org T; Chignola F; Hetényi C; Gaetani M; Rebane A; Liiv I; Maran U; Mollica L; Bottomley MJ; Musco G; Peterson P
    EMBO Rep; 2008 Apr; 9(4):370-6. PubMed ID: 18292755
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity.
    Koh AS; Kuo AJ; Park SY; Cheung P; Abramson J; Bua D; Carney D; Shoelson SE; Gozani O; Kingston RE; Benoist C; Mathis D
    Proc Natl Acad Sci U S A; 2008 Oct; 105(41):15878-83. PubMed ID: 18840680
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comprehensively Profiling the Chromatin Architecture of Tissue Restricted Antigen Expression in Thymic Epithelial Cells Over Development.
    Handel AE; Shikama-Dorn N; Zhanybekova S; Maio S; Graedel AN; Zuklys S; Ponting CP; Holländer GA
    Front Immunol; 2018; 9():2120. PubMed ID: 30283453
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation.
    Chignola F; Gaetani M; Rebane A; Org T; Mollica L; Zucchelli C; Spitaleri A; Mannella V; Peterson P; Musco G
    Nucleic Acids Res; 2009 May; 37(9):2951-61. PubMed ID: 19293276
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA methylation signatures of the AIRE promoter in thymic epithelial cells, thymomas and normal tissues.
    Kont V; Murumägi A; Tykocinski LO; Kinkel SA; Webster KE; Kisand K; Tserel L; Pihlap M; Ströbel P; Scott HS; Marx A; Kyewski B; Peterson P
    Mol Immunol; 2011 Dec; 49(3):518-26. PubMed ID: 22036612
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PHD finger of autoimmune regulator: an epigenetic link between the histone modifications and tissue-specific antigen expression in thymus.
    Musco G; Peterson P
    Epigenetics; 2008 Nov; 3(6):310-4. PubMed ID: 19011376
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Patient mutation in AIRE disrupts P-TEFb binding and target gene transcription.
    Žumer K; Plemenitaš A; Saksela K; Peterlin BM
    Nucleic Acids Res; 2011 Oct; 39(18):7908-19. PubMed ID: 21724609
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells.
    Giraud M; Yoshida H; Abramson J; Rahl PB; Young RA; Mathis D; Benoist C
    Proc Natl Acad Sci U S A; 2012 Jan; 109(2):535-40. PubMed ID: 22203960
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of histone modifications in marking and activating genes through mitosis.
    Valls E; Sánchez-Molina S; Martínez-Balbás MA
    J Biol Chem; 2005 Dec; 280(52):42592-600. PubMed ID: 16199528
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chromatin signature of embryonic pluripotency is established during genome activation.
    Vastenhouw NL; Zhang Y; Woods IG; Imam F; Regev A; Liu XS; Rinn J; Schier AF
    Nature; 2010 Apr; 464(7290):922-6. PubMed ID: 20336069
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genome-wide promoter analysis of histone modifications in human monocyte-derived antigen presenting cells.
    Tserel L; Kolde R; Rebane A; Kisand K; Org T; Peterson H; Vilo J; Peterson P
    BMC Genomics; 2010 Nov; 11():642. PubMed ID: 21087476
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Overexpressing autoimmune regulator regulates the expression of toll-like receptors by interacting with their promoters in RAW264.7 cells.
    Zhu W; Yang W; He Z; Liao X; Wu J; Sun J; Yang Y; Li Y
    Cell Immunol; 2011; 270(2):156-63. PubMed ID: 21628060
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Autoimmune regulator (Aire) controls the expression of microRNAs in medullary thymic epithelial cells.
    Macedo C; Evangelista AF; Marques MM; Octacílio-Silva S; Donadi EA; Sakamoto-Hojo ET; Passos GA
    Immunobiology; 2013 Apr; 218(4):554-60. PubMed ID: 22883565
    [TBL] [Abstract][Full Text] [Related]  

  • 18. AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome.
    Gaetani M; Matafora V; Saare M; Spiliotopoulos D; Mollica L; Quilici G; Chignola F; Mannella V; Zucchelli C; Peterson P; Bachi A; Musco G
    Nucleic Acids Res; 2012 Dec; 40(22):11756-68. PubMed ID: 23074189
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The biophysical and biochemical properties of the autoimmune regulator (AIRE) protein.
    Perniola R; Musco G
    Biochim Biophys Acta; 2014 Feb; 1842(2):326-37. PubMed ID: 24275490
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of regulatory elements and methylation pattern of the autoimmune regulator (AIRE) promoter.
    Murumägi A; Vähämurto P; Peterson P
    J Biol Chem; 2003 May; 278(22):19784-90. PubMed ID: 12651856
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.