These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 19747481)

  • 1. Signaling effect of amyloid-beta(42) on the processing of AbetaPP.
    Tabaton M; Zhu X; Perry G; Smith MA; Giliberto L
    Exp Neurol; 2010 Jan; 221(1):18-25. PubMed ID: 19747481
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.
    Kimura A; Hata S; Suzuki T
    J Biol Chem; 2016 Nov; 291(46):24041-24053. PubMed ID: 27687728
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Amyloid-β₄₂ activates the expression of BACE1 through the JNK pathway.
    Guglielmotto M; Monteleone D; Giliberto L; Fornaro M; Borghi R; Tamagno E; Tabaton M
    J Alzheimers Dis; 2011; 27(4):871-83. PubMed ID: 21897006
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease.
    Chen CH; Zhou W; Liu S; Deng Y; Cai F; Tone M; Tone Y; Tong Y; Song W
    Int J Neuropsychopharmacol; 2012 Feb; 15(1):77-90. PubMed ID: 21329555
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation.
    Marwarha G; Rostad S; Lilek J; Kleinjan M; Schommer J; Ghribi O
    J Alzheimers Dis; 2017; 57(3):907-925. PubMed ID: 28304295
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein.
    Tamagno E; Guglielmotto M; Aragno M; Borghi R; Autelli R; Giliberto L; Muraca G; Danni O; Zhu X; Smith MA; Perry G; Jo DG; Mattson MP; Tabaton M
    J Neurochem; 2008 Feb; 104(3):683-95. PubMed ID: 18005001
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Swedish mutant APP-based BACE1 binding site peptide reduces APP β-cleavage and cerebral Aβ levels in Alzheimer's mice.
    Li S; Hou H; Mori T; Sawmiller D; Smith A; Tian J; Wang Y; Giunta B; Sanberg PR; Zhang S; Tan J
    Sci Rep; 2015 Jun; 5():11322. PubMed ID: 26091071
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis.
    O'Connor T; Sadleir KR; Maus E; Velliquette RA; Zhao J; Cole SL; Eimer WA; Hitt B; Bembinster LA; Lammich S; Lichtenthaler SF; Hébert SS; De Strooper B; Haass C; Bennett DA; Vassar R
    Neuron; 2008 Dec; 60(6):988-1009. PubMed ID: 19109907
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amyloid-β production: major link between oxidative stress and BACE1.
    Tamagno E; Guglielmotto M; Monteleone D; Tabaton M
    Neurotox Res; 2012 Oct; 22(3):208-19. PubMed ID: 22002808
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
    Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
    Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The β-Secretase Enzyme BACE1: A Biochemical Enigma for Alzheimer's Disease.
    Shah H; Patel A; Parikh V; Nagani A; Bhimani B; Shah U; Bambharoliya T
    CNS Neurol Disord Drug Targets; 2020; 19(3):184-194. PubMed ID: 32452328
    [TBL] [Abstract][Full Text] [Related]  

  • 13. New BACE1 Chimeric Peptide Inhibitors Selectively Prevent AβPP-β Cleavage Decreasing Amyloid-β Production and Accumulation in Alzheimer's Disease Models.
    Resende R; Ferreira-Marques M; Moreira P; Coimbra JRM; Baptista SJ; Isidoro C; Salvador JAR; Dinis TCP; Pereira CF; Santos AE
    J Alzheimers Dis; 2020; 76(4):1317-1337. PubMed ID: 32597812
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The BACE1-PSEN-AβPP regulatory axis has an ancient role in response to low oxygen/oxidative stress.
    Moussavi Nik SH; Wilson L; Newman M; Croft K; Mori TA; Musgrave I; Lardelli M
    J Alzheimers Dis; 2012; 28(3):515-30. PubMed ID: 22045484
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reduction of the expression of the late-onset Alzheimer's disease (AD) risk-factor
    Andrew RJ; De Rossi P; Nguyen P; Kowalski HR; Recupero AJ; Guerbette T; Krause SV; Rice RC; Laury-Kleintop L; Wagner SL; Thinakaran G
    J Biol Chem; 2019 Mar; 294(12):4477-4487. PubMed ID: 30692199
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Thiamine deficiency increases β-secretase activity and accumulation of β-amyloid peptides.
    Zhang Q; Yang G; Li W; Fan Z; Sun A; Luo J; Ke ZJ
    Neurobiol Aging; 2011 Jan; 32(1):42-53. PubMed ID: 19233513
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Beta-secretase/BACE1 promotes APP endocytosis and processing in the endosomes and on cell membrane.
    Wang M; Jing T; Wang X; Yao D
    Neurosci Lett; 2018 Oct; 685():63-67. PubMed ID: 30120949
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
    Ye X; Feng T; Tammineni P; Chang Q; Jeong YY; Margolis DJ; Cai H; Kusnecov A; Cai Q
    J Neurosci; 2017 Mar; 37(10):2639-2655. PubMed ID: 28159908
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of senescence and angiotensin II on expression and processing of amyloid precursor protein in human cerebral microvascular endothelial cells.
    Sun R; He T; Pan Y; Katusic ZS
    Aging (Albany NY); 2018 Jan; 10(1):100-114. PubMed ID: 29348391
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells.
    Chen LM; Lin ZY; Zhu YG; Lin N; Zhang J; Pan XD; Chen XC
    Eur J Pharmacol; 2012 Jan; 675(1-3):15-21. PubMed ID: 22166376
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.