BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 19748906)

  • 1. Endothelin signalling in arterial smooth muscle is tightly regulated by G protein-coupled receptor kinase 2.
    Morris GE; Nelson CP; Standen NB; Challiss RA; Willets JM
    Cardiovasc Res; 2010 Feb; 85(3):424-33. PubMed ID: 19748906
    [TBL] [Abstract][Full Text] [Related]  

  • 2. G protein-coupled receptor kinase 2 and arrestin2 regulate arterial smooth muscle P2Y-purinoceptor signalling.
    Morris GE; Nelson CP; Everitt D; Brighton PJ; Standen NB; Challiss RA; Willets JM
    Cardiovasc Res; 2011 Jan; 89(1):193-203. PubMed ID: 20705669
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Small-Molecule G Protein-Coupled Receptor Kinase Inhibitors Attenuate G Protein-Coupled Receptor Kinase 2-Mediated Desensitization of Vasoconstrictor-Induced Arterial Contractions.
    Rainbow RD; Brennan S; Jackson R; Beech AJ; Bengreed A; Waldschmidt HV; Tesmer JJG; Challiss RAJ; Willets JM
    Mol Pharmacol; 2018 Sep; 94(3):1079-1091. PubMed ID: 29980659
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Arrestins 2 and 3 differentially regulate ETA and P2Y2 receptor-mediated cell signaling and migration in arterial smooth muscle.
    Morris GE; Nelson CP; Brighton PJ; Standen NB; Challiss RA; Willets JM
    Am J Physiol Cell Physiol; 2012 Mar; 302(5):C723-34. PubMed ID: 22159081
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Roles of phosphorylation-dependent and -independent mechanisms in the regulation of M1 muscarinic acetylcholine receptors by G protein-coupled receptor kinase 2 in hippocampal neurons.
    Willets JM; Nahorski SR; Challiss RA
    J Biol Chem; 2005 May; 280(19):18950-8. PubMed ID: 15743771
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential regulation of β
    Nash CA; Nelson CP; Mistry R; Moeller-Olsen C; Christofidou E; Challiss RAJ; Willets JM
    Cell Signal; 2018 Nov; 51():86-98. PubMed ID: 30075183
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphorylation and desensitization of human endothelin A and B receptors. Evidence for G protein-coupled receptor kinase specificity.
    Freedman NJ; Ament AS; Oppermann M; Stoffel RH; Exum ST; Lefkowitz RJ
    J Biol Chem; 1997 Jul; 272(28):17734-43. PubMed ID: 9211925
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selective regulation of H1 histamine receptor signaling by G protein-coupled receptor kinase 2 in uterine smooth muscle cells.
    Willets JM; Taylor AH; Shaw H; Konje JC; Challiss RA
    Mol Endocrinol; 2008 Aug; 22(8):1893-907. PubMed ID: 18511496
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Endogenous G protein-coupled receptor kinase 6 triggers homologous beta-adrenergic receptor desensitization in primary uterine smooth muscle cells.
    Simon V; Robin MT; Legrand C; Cohen-Tannoudji J
    Endocrinology; 2003 Jul; 144(7):3058-66. PubMed ID: 12810562
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enhanced expression of Gqα and PLC-β1 proteins contributes to vascular smooth muscle cell hypertrophy in SHR: role of endogenous angiotensin II and endothelin-1.
    Atef ME; Anand-Srivastava MB
    Am J Physiol Cell Physiol; 2014 Jul; 307(1):C97-106. PubMed ID: 24760983
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Darusentan is a potent inhibitor of endothelin signaling and function in both large and small arteries.
    Liang F; Glascock CB; Schafer DL; Sandoval J; Cable L; Melvin L; Hartman JC; Pitts KR
    Can J Physiol Pharmacol; 2010 Aug; 88(8):840-9. PubMed ID: 20725142
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Imaging of muscarinic acetylcholine receptor signaling in hippocampal neurons: evidence for phosphorylation-dependent and -independent regulation by G-protein-coupled receptor kinases.
    Willets JM; Nash MS; Challiss RA; Nahorski SR
    J Neurosci; 2004 Apr; 24(17):4157-62. PubMed ID: 15115810
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Desensitization and internalization of endothelin receptor A: impact of G protein-coupled receptor kinase 2 (GRK2)-mediated phosphorylation.
    Gärtner F; Seidel T; Schulz U; Gummert J; Milting H
    J Biol Chem; 2013 Nov; 288(45):32138-32148. PubMed ID: 24064210
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective regulation of G protein-coupled receptor-mediated signaling by G protein-coupled receptor kinase 2 in FRTL-5 cells: analysis of thyrotropin, alpha(1B)-adrenergic, and A(1) adenosine receptor-mediated responses.
    Iacovelli L; Franchetti R; Grisolia D; De Blasi A
    Mol Pharmacol; 1999 Aug; 56(2):316-24. PubMed ID: 10419550
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bimodal regulation of the human H1 histamine receptor by G protein-coupled receptor kinase 2.
    Iwata K; Luo J; Penn RB; Benovic JL
    J Biol Chem; 2005 Jan; 280(3):2197-204. PubMed ID: 15542600
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ca2+ signalling by endothelin receptors in rat and human cultured airway smooth muscle cells.
    Maxwell MJ; Goldie RG; Henry PJ
    Br J Pharmacol; 1998 Dec; 125(8):1768-78. PubMed ID: 9886769
    [TBL] [Abstract][Full Text] [Related]  

  • 17. G protein-coupled receptor kinase 2 mediates endothelin-1-induced insulin resistance via the inhibition of both Galphaq/11 and insulin receptor substrate-1 pathways in 3T3-L1 adipocytes.
    Usui I; Imamura T; Babendure JL; Satoh H; Lu JC; Hupfeld CJ; Olefsky JM
    Mol Endocrinol; 2005 Nov; 19(11):2760-8. PubMed ID: 15994203
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Relaxin, a pregnancy hormone, is a functional endothelin-1 antagonist: attenuation of endothelin-1-mediated vasoconstriction by stimulation of endothelin type-B receptor expression via ERK-1/2 and nuclear factor-kappaB.
    Dschietzig T; Bartsch C; Richter C; Laule M; Baumann G; Stangl K
    Circ Res; 2003 Jan; 92(1):32-40. PubMed ID: 12522118
    [TBL] [Abstract][Full Text] [Related]  

  • 19. GRK2 expression and catalytic activity are essential for vasoconstrictor/ERK-stimulated arterial smooth muscle proliferation.
    Alonazi A; Nash CA; Wang CH; Christofidou E; Challiss RAJ; Willets JM
    Biochem Pharmacol; 2023 Oct; 216():115795. PubMed ID: 37690571
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphorylation of GRK2 by PKA augments GRK2-mediated phosphorylation, internalization, and desensitization of VPAC2 receptors in smooth muscle.
    Murthy KS; Mahavadi S; Huang J; Zhou H; Sriwai W
    Am J Physiol Cell Physiol; 2008 Feb; 294(2):C477-87. PubMed ID: 18077607
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.