BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 19751795)

  • 1. Microgram-order ammonium perfluorooctanoate may activate mouse peroxisome proliferator-activated receptor alpha, but not human PPARalpha.
    Nakamura T; Ito Y; Yanagiba Y; Ramdhan DH; Kono Y; Naito H; Hayashi Y; Li Y; Aoyama T; Gonzalez FJ; Nakajima T
    Toxicology; 2009 Nov; 265(1-2):27-33. PubMed ID: 19751795
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modulation of ammonium perfluorooctanoate-induced hepatic damage by genetically different PPARα in mice.
    Nakagawa T; Ramdhan DH; Tanaka N; Naito H; Tamada H; Ito Y; Li Y; Hayashi Y; Yamagishi N; Yanagiba Y; Aoyama T; Gonzalez FJ; Nakajima T
    Arch Toxicol; 2012 Jan; 86(1):63-74. PubMed ID: 21499893
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ammonium perfluorooctanoate may cause testosterone reduction by adversely affecting testis in relation to PPARα.
    Li Y; Ramdhan DH; Naito H; Yamagishi N; Ito Y; Hayashi Y; Yanagiba Y; Okamura A; Tamada H; Gonzalez FJ; Nakajima T
    Toxicol Lett; 2011 Sep; 205(3):265-72. PubMed ID: 21712084
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Perfluorooctanoic acid activates multiple nuclear receptor pathways and skews expression of genes regulating cholesterol homeostasis in liver of humanized PPARα mice fed an American diet.
    Schlezinger JJ; Puckett H; Oliver J; Nielsen G; Heiger-Bernays W; Webster TF
    Toxicol Appl Pharmacol; 2020 Oct; 405():115204. PubMed ID: 32822737
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A species difference in the peroxisome proliferator-activated receptor α-dependent response to the developmental effects of perfluorooctanoic acid.
    Albrecht PP; Torsell NE; Krishnan P; Ehresman DJ; Frame SR; Chang SC; Butenhoff JL; Kennedy GL; Gonzalez FJ; Peters JM
    Toxicol Sci; 2013 Feb; 131(2):568-82. PubMed ID: 23143925
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hepatic peroxisome proliferator-activated receptor α may have an important role in the toxic effects of di(2-ethylhexyl)phthalate on offspring of mice.
    Hayashi Y; Ito Y; Yamagishi N; Yanagiba Y; Tamada H; Wang D; Ramdhan DH; Naito H; Harada Y; Kamijima M; Gonzales FJ; Nakajima T
    Toxicology; 2011 Oct; 289(1):1-10. PubMed ID: 21354252
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Perfluorooctanoic acid induces liver and serum dyslipidemia in humanized PPARα mice fed an American diet.
    Schlezinger JJ; Hyötyläinen T; Sinioja T; Boston C; Puckett H; Oliver J; Heiger-Bernays W; Webster TF
    Toxicol Appl Pharmacol; 2021 Sep; 426():115644. PubMed ID: 34252412
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of mouse and human peroxisome proliferator-activated receptor-α in modulating the hepatic effects of perfluorooctane sulfonate in mice.
    Su S; Billy LJ; Chang S; Gonzalez FJ; Patterson AD; Peters JM
    Toxicology; 2022 Jan; 465():153056. PubMed ID: 34861291
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Perfluorooctanoic acid induced developmental toxicity in the mouse is dependent on expression of peroxisome proliferator activated receptor-alpha.
    Abbott BD; Wolf CJ; Schmid JE; Das KP; Zehr RD; Helfant L; Nakayama S; Lindstrom AB; Strynar MJ; Lau C
    Toxicol Sci; 2007 Aug; 98(2):571-81. PubMed ID: 17488742
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hepatic and renal Bcrp transporter expression in mice treated with perfluorooctanoic acid.
    Eldasher LM; Wen X; Little MS; Bircsak KM; Yacovino LL; Aleksunes LM
    Toxicology; 2013 Apr; 306():108-13. PubMed ID: 23435180
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of peroxisome proliferator-activated receptor-alpha in hepatobiliary injury induced by ammonium perfluorooctanoate in mouse liver.
    Minata M; Harada KH; Kärrman A; Hitomi T; Hirosawa M; Murata M; Gonzalez FJ; Koizumi A
    Ind Health; 2010; 48(1):96-107. PubMed ID: 20160413
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Toxicogenomic dissection of the perfluorooctanoic acid transcript profile in mouse liver: evidence for the involvement of nuclear receptors PPAR alpha and CAR.
    Rosen MB; Lee JS; Ren H; Vallanat B; Liu J; Waalkes MP; Abbott BD; Lau C; Corton JC
    Toxicol Sci; 2008 May; 103(1):46-56. PubMed ID: 18281256
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gene profiling in the livers of wild-type and PPARalpha-null mice exposed to perfluorooctanoic acid.
    Rosen MB; Abbott BD; Wolf DC; Corton JC; Wood CR; Schmid JE; Das KP; Zehr RD; Blair ET; Lau C
    Toxicol Pathol; 2008 Jun; 36(4):592-607. PubMed ID: 18467677
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Importance of PPAR alpha for the effects of growth hormone on hepatic lipid and lipoprotein metabolism.
    Ljungberg A; Lindén D; Améen C; Bergström G; Oscarsson J
    Growth Horm IGF Res; 2007 Apr; 17(2):154-64. PubMed ID: 17307376
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transcription of genes involved in fat metabolism in chicken embryos exposed to the peroxisome proliferator-activated receptor alpha (PPARα) agonist GW7647 or to perfluorooctane sulfonate (PFOS) or perfluorooctanoic acid (PFOA).
    Strömqvist M; Olsson JA; Kärrman A; Brunström B
    Comp Biochem Physiol C Toxicol Pharmacol; 2012 Jun; 156(1):29-36. PubMed ID: 22465071
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hepatic carboxylesterases are differentially regulated in PPARα-null mice treated with perfluorooctanoic acid.
    Wen X; Baker AA; Klaassen CD; Corton JC; Richardson JR; Aleksunes LM
    Toxicology; 2019 Mar; 416():15-22. PubMed ID: 30685356
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential hepatic effects of perfluorobutyrate mediated by mouse and human PPAR-alpha.
    Foreman JE; Chang SC; Ehresman DJ; Butenhoff JL; Anderson CR; Palkar PS; Kang BH; Gonzalez FJ; Peters JM
    Toxicol Sci; 2009 Jul; 110(1):204-11. PubMed ID: 19359353
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential response to trichloroethylene-induced hepatosteatosis in wild-type and PPARalpha-humanized mice.
    Ramdhan DH; Kamijima M; Wang D; Ito Y; Naito H; Yanagiba Y; Hayashi Y; Tanaka N; Aoyama T; Gonzalez FJ; Nakajima T
    Environ Health Perspect; 2010 Nov; 118(11):1557-63. PubMed ID: 20709644
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The effects of perfluorooctanoate on high fat diet induced non-alcoholic fatty liver disease in mice.
    Li X; Wang Z; Klaunig JE
    Toxicology; 2019 Mar; 416():1-14. PubMed ID: 30711707
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Perfluorooctanoic Acid (PFOA)-induced Liver Lesions in Two Strains of Mice Following Developmental Exposures: PPARα Is Not Required.
    Filgo AJ; Quist EM; Hoenerhoff MJ; Brix AE; Kissling GE; Fenton SE
    Toxicol Pathol; 2015 Jun; 43(4):558-68. PubMed ID: 25398757
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.