223 related articles for article (PubMed ID: 19756449)
1. Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation.
Amato R; D'Antona L; Porciatti G; Agosti V; Menniti M; Rinaldo C; Costa N; Bellacchio E; Mattarocci S; Fuiano G; Soddu S; Paggi MG; Lang F; Perrotti N
J Mol Med (Berl); 2009 Dec; 87(12):1221-39. PubMed ID: 19756449
[TBL] [Abstract][Full Text] [Related]
2. Diverse effects of ANXA7 and p53 on LNCaP prostate cancer cells are associated with regulation of SGK1 transcription and phosphorylation of the SGK1 target FOXO3A.
Srivastava M; Leighton X; Starr J; Eidelman O; Pollard HB
Biomed Res Int; 2014; 2014():193635. PubMed ID: 24864229
[TBL] [Abstract][Full Text] [Related]
3. SGK1 inhibits cellular apoptosis and promotes proliferation via the MEK/ERK/p53 pathway in colitis.
Bai JA; Xu GF; Yan LJ; Zeng WW; Ji QQ; Wu JD; Tang QY
World J Gastroenterol; 2015 May; 21(20):6180-93. PubMed ID: 26034353
[TBL] [Abstract][Full Text] [Related]
4. SI113, a specific inhibitor of the Sgk1 kinase activity that counteracts cancer cell proliferation.
D'Antona L; Amato R; Talarico C; Ortuso F; Menniti M; Dattilo V; Iuliano R; Gigliotti F; Artese A; Costa G; Schenone S; Musumeci F; Abbruzzese C; Botta L; Trapasso F; Alcaro S; Paggi MG; Perrotti N
Cell Physiol Biochem; 2015; 35(5):2006-18. PubMed ID: 25871776
[TBL] [Abstract][Full Text] [Related]
5. Colorectal carcinoma cells--regulation of survival and growth by SGK1.
Lang F; Perrotti N; Stournaras C
Int J Biochem Cell Biol; 2010 Oct; 42(10):1571-5. PubMed ID: 20541034
[TBL] [Abstract][Full Text] [Related]
6. Pivotal role of serum- and glucocorticoid-inducible kinase 1 in vascular inflammation and atherogenesis.
Borst O; Schaub M; Walker B; Schmid E; Münzer P; Voelkl J; Alesutan I; Rodríguez JM; Vogel S; Schoenberger T; Metzger K; Rath D; Umbach A; Kuhl D; Müller II; Seizer P; Geisler T; Gawaz M; Lang F
Arterioscler Thromb Vasc Biol; 2015 Mar; 35(3):547-57. PubMed ID: 25614279
[TBL] [Abstract][Full Text] [Related]
7. Circular RNA circ_0007142 regulates cell proliferation, apoptosis, migration and invasion via miR-455-5p/SGK1 axis in colorectal cancer.
Wen T; Wu H; Zhang L; Li K; Xiao X; Zhang L; Zhang Y
Anticancer Drugs; 2021 Jan; 32(1):22-33. PubMed ID: 32889894
[TBL] [Abstract][Full Text] [Related]
8. Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase.
Mo JS; Ann EJ; Yoon JH; Jung J; Choi YH; Kim HY; Ahn JS; Kim SM; Kim MY; Hong JA; Seo MS; Lang F; Choi EJ; Park HS
J Cell Sci; 2011 Jan; 124(Pt 1):100-12. PubMed ID: 21147854
[TBL] [Abstract][Full Text] [Related]
9. Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells.
Fagerli UM; Ullrich K; Stühmer T; Holien T; Köchert K; Holt RU; Bruland O; Chatterjee M; Nogai H; Lenz G; Shaughnessy JD; Mathas S; Sundan A; Bargou RC; Dörken B; Børset M; Janz M
Oncogene; 2011 Jul; 30(28):3198-206. PubMed ID: 21478911
[TBL] [Abstract][Full Text] [Related]
10. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
Lu X; Ma O; Nguyen TA; Jones SN; Oren M; Donehower LA
Cancer Cell; 2007 Oct; 12(4):342-54. PubMed ID: 17936559
[TBL] [Abstract][Full Text] [Related]
11. Counteracting MDM2-induced HIPK2 downregulation restores HIPK2/p53 apoptotic signaling in cancer cells.
Nardinocchi L; Puca R; Givol D; D'Orazi G
FEBS Lett; 2010 Oct; 584(19):4253-8. PubMed ID: 20849851
[TBL] [Abstract][Full Text] [Related]
12. microRNA-1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesis.
Zhang C; Liu J; Tan C; Yue X; Zhao Y; Peng J; Wang X; Laddha SV; Chan CS; Zheng S; Hu W; Feng Z
Oncotarget; 2016 Feb; 7(8):8783-96. PubMed ID: 26840028
[TBL] [Abstract][Full Text] [Related]
13. Serum- and Glucocorticoid-induced Kinase Sgk1 Directly Promotes the Differentiation of Colorectal Cancer Cells and Restrains Metastasis.
Lee LYW; Woolley C; Starkey T; Biswas S; Mirshahi T; Bardella C; Segditsas S; Irshad S; Tomlinson I
Clin Cancer Res; 2019 Jan; 25(2):629-640. PubMed ID: 30322876
[TBL] [Abstract][Full Text] [Related]
14. Chronic restraint stress attenuates p53 function and promotes tumorigenesis.
Feng Z; Liu L; Zhang C; Zheng T; Wang J; Lin M; Zhao Y; Wang X; Levine AJ; Hu W
Proc Natl Acad Sci U S A; 2012 May; 109(18):7013-8. PubMed ID: 22509031
[TBL] [Abstract][Full Text] [Related]
15. Serine/threonine protein kinase SGK1 in glucocorticoid-dependent transdifferentiation of pancreatic acinar cells to hepatocytes.
Wallace K; Long Q; Fairhall EA; Charlton KA; Wright MC
J Cell Sci; 2011 Feb; 124(Pt 3):405-13. PubMed ID: 21224398
[TBL] [Abstract][Full Text] [Related]
16. Cytoplasmic translocation of MTA1 coregulator promotes de-repression of SGK1 transcription in hypoxic cancer cells.
Marzook H; Deivendran S; George B; Reshmi G; Santhoshkumar TR; Kumar R; Pillai MR
Oncogene; 2017 Sep; 36(37):5263-5273. PubMed ID: 28504714
[TBL] [Abstract][Full Text] [Related]
17. Serum/glucocorticoid-regulated kinase 1 as a novel transcriptional target of bone morphogenetic protein-ALK1 receptor signaling in vascular endothelial cells.
Araki M; Hisamitsu T; Kinugasa-Katayama Y; Tanaka T; Harada Y; Nakao S; Hanada S; Ishii S; Fujita M; Kawamura T; Saito Y; Nishiyama K; Watanabe Y; Nakagawa O
Angiogenesis; 2018 May; 21(2):415-423. PubMed ID: 29478089
[TBL] [Abstract][Full Text] [Related]
18. Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy.
Talarico C; D'Antona L; Scumaci D; Barone A; Gigliotti F; Fiumara CV; Dattilo V; Gallo E; Visca P; Ortuso F; Abbruzzese C; Botta L; Schenone S; Cuda G; Alcaro S; Bianco C; Lavia P; Paggi MG; Perrotti N; Amato R
Oncotarget; 2015 Nov; 6(35):37511-25. PubMed ID: 26462020
[TBL] [Abstract][Full Text] [Related]
19. The oncoprotein HBXIP promotes human breast cancer growth through down-regulating p53 via miR-18b/MDM2 and pAKT/MDM2 pathways.
Li H; Wang Z; Jiang M; Fang RP; Shi H; Shen Y; Cai XL; Liu Q; Ye K; Fan SJ; Zhang WY; Ye LH
Acta Pharmacol Sin; 2018 Nov; 39(11):1787-1796. PubMed ID: 30181579
[TBL] [Abstract][Full Text] [Related]
20. Serum and Glucocorticoid Inducible Kinase 1-Sensitive Survival, Proliferation and Migration of Rhabdomyosarcoma Cells.
Schmid E; Stagno MJ; Yan J; Schleicher S; Yu W; Honisch S; Lang F; Fuchs J; Seitz G
Cell Physiol Biochem; 2017; 43(3):1301-1308. PubMed ID: 28992614
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]