These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

248 related articles for article (PubMed ID: 19760730)

  • 21. Synthesis and biological characterization of the histone deacetylase inhibitor largazole and C7- modified analogues.
    Souto JA; Vaz E; Lepore I; Pöppler AC; Franci G; Alvarez R; Altucci L; de Lera AR
    J Med Chem; 2010 Jun; 53(12):4654-67. PubMed ID: 20491440
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Amide-based derivatives of β-alanine hydroxamic acid as histone deacetylase inhibitors: attenuation of potency through resonance effects.
    Liao V; Liu T; Codd R
    Bioorg Med Chem Lett; 2012 Oct; 22(19):6200-4. PubMed ID: 22932316
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Discovery of Novel Class I Histone Deacetylase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities.
    Yao Y; Tu Z; Liao C; Wang Z; Li S; Yao H; Li Z; Jiang S
    J Med Chem; 2015 Oct; 58(19):7672-80. PubMed ID: 26331334
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis and Preliminary Biological Evaluation of Two Fluoroolefin Analogs of Largazole Inspired by the Structural Similarity of the Side Chain Unit in Psammaplin A.
    Zhang B; Shan G; Zheng Y; Yu X; Ruan ZW; Li Y; Lei X
    Mar Drugs; 2019 Jun; 17(6):. PubMed ID: 31163697
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis and biological evaluation of largazole analogues with modified surface recognition cap groups.
    Bhansali P; Hanigan CL; Perera L; Casero RA; Tillekeratne LM
    Eur J Med Chem; 2014 Oct; 86():528-41. PubMed ID: 25203782
    [TBL] [Abstract][Full Text] [Related]  

  • 26. New macrocyclic analogs of the natural histone deacetylase inhibitor FK228; design, synthesis and preliminary biological evaluation.
    Ni M; Esposito E; Raj VP; Muzi L; Zunino F; Zuco V; Cominetti D; Penco S; Dal Pozzo A
    Bioorg Med Chem; 2015 Nov; 23(21):6785-93. PubMed ID: 26481659
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222.
    Terracciano S; Di Micco S; Bifulco G; Gallinari P; Riccio R; Bruno I
    Bioorg Med Chem; 2010 May; 18(9):3252-60. PubMed ID: 20381359
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Synthesis and biological characterization of amidopropenyl hydroxamates as HDAC inhibitors.
    Thaler F; Varasi M; Colombo A; Boggio R; Munari D; Regalia N; Rozio MG; Reali V; Resconi AE; Mai A; Gagliardi S; Dondio G; Minucci S; Mercurio C
    ChemMedChem; 2010 Aug; 5(8):1359-72. PubMed ID: 20572281
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Histone deacetylase inhibitors from Burkholderia thailandensis.
    Klausmeyer P; Shipley SM; Zuck KM; McCloud TG
    J Nat Prod; 2011 Oct; 74(10):2039-44. PubMed ID: 21967146
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Discovery of potent HDAC inhibitors based on chlamydocin with inhibitory effects on cell migration.
    Wang S; Li X; Wei Y; Xiu Z; Nishino N
    ChemMedChem; 2014 Mar; 9(3):627-37. PubMed ID: 24285590
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Largazole Analogues Embodying Radical Changes in the Depsipeptide Ring: Development of a More Selective and Highly Potent Analogue.
    Almaliti J; Al-Hamashi AA; Negmeldin AT; Hanigan CL; Perera L; Pflum MK; Casero RA; Tillekeratne LM
    J Med Chem; 2016 Dec; 59(23):10642-10660. PubMed ID: 27809521
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Modular synthesis and biological activity of pyridyl-based analogs of the potent Class I Histone Deacetylase Inhibitor Largazole.
    Clausen DJ; Smith WB; Haines BE; Wiest O; Bradner JE; Williams RM
    Bioorg Med Chem; 2015 Aug; 23(15):5061-5074. PubMed ID: 26054247
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synthesis, evaluation and molecular modeling of cyclic tetrapeptide histone deacetylase inhibitors as anticancer agents.
    Huang D; Li X; Sun L; Xiu Z; Nishino N
    J Pept Sci; 2012 Apr; 18(4):242-51. PubMed ID: 22253009
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Design and Synthesis of Simplified Largazole Analogues as Isoform-Selective Human Lysine Deacetylase Inhibitors.
    Reddy DN; Ballante F; Chuang T; Pirolli A; Marrocco B; Marshall GR
    J Med Chem; 2016 Feb; 59(4):1613-33. PubMed ID: 26681404
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Largazole Analogues as Histone Deacetylase Inhibitors and Anticancer Agents: An Overview of Structure-Activity Relationships.
    Poli G; Di Fabio R; Ferrante L; Summa V; Botta M
    ChemMedChem; 2017 Dec; 12(23):1917-1926. PubMed ID: 29117473
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Total synthesis of largazole and analogues: HDAC inhibition, antiproliferative activity and metabolic stability.
    Benelkebir H; Marie S; Hayden AL; Lyle J; Loadman PM; Crabb SJ; Packham G; Ganesan A
    Bioorg Med Chem; 2011 Jun; 19(12):3650-8. PubMed ID: 21420302
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Spiruchostatin A and B, novel histone deacetylase inhibitors, induce apoptosis through reactive oxygen species-mitochondria pathway in human lymphoma U937 cells.
    Rehman MU; Jawaid P; Yoshihisa Y; Li P; Zhao QL; Narita K; Katoh T; Kondo T; Shimizu T
    Chem Biol Interact; 2014 Sep; 221():24-34. PubMed ID: 25078973
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Design, synthesis and preliminary activity assay of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as novel Histone deacetylases (HDACs) inhibitors.
    Zhang Y; Feng J; Liu C; Zhang L; Jiao J; Fang H; Su L; Zhang X; Zhang J; Li M; Wang B; Xu W
    Bioorg Med Chem; 2010 Mar; 18(5):1761-72. PubMed ID: 20171895
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Identification of a series of substituted 2-piperazinyl-5-pyrimidylhydroxamic acids as potent histone deacetylase inhibitors.
    Angibaud P; Van Emelen K; Decrane L; van Brandt S; Ten Holte P; Pilatte I; Roux B; Poncelet V; Speybrouck D; Queguiner L; Gaurrand S; Mariën A; Floren W; Janssen L; Verdonck M; van Dun J; van Gompel J; Gilissen R; Mackie C; Du Jardin M; Peeters J; Noppe M; Van Hijfte L; Freyne E; Page M; Janicot M; Arts J
    Bioorg Med Chem Lett; 2010 Jan; 20(1):294-8. PubMed ID: 19906529
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Largazole and analogues with modified metal-binding motifs targeting histone deacetylases: synthesis and biological evaluation.
    Bhansali P; Hanigan CL; Casero RA; Tillekeratne LM
    J Med Chem; 2011 Nov; 54(21):7453-63. PubMed ID: 21936551
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.