106 related articles for article (PubMed ID: 19762246)
1. Synthesis of 2- and 17-substituted estrone analogs and their antiproliferative structure-activity relationships compared to 2-methoxyestradiol.
Shah JH; Agoston GE; Suwandi L; Hunsucker K; Pribluda V; Zhan XH; Swartz GM; LaVallee TM; Treston AM
Bioorg Med Chem; 2009 Oct; 17(20):7344-52. PubMed ID: 19762246
[TBL] [Abstract][Full Text] [Related]
2. Synthesis, antiproliferative, and pharmacokinetic properties of 3- and 17-double-modified analogs of 2-methoxyestradiol.
Agoston GE; Shah JH; Suwandi L; Hanson AD; Zhan X; LaVallee TM; Pribluda V; Treston AM
Bioorg Med Chem Lett; 2009 Nov; 19(21):6241-4. PubMed ID: 19782564
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and antitumor activities of 3-modified 2-methoxyestradiol analogs.
Suwandi LS; Agoston GE; Shah JH; Hanson AD; Zhan XH; Lavallee TM; Treston AM
Bioorg Med Chem Lett; 2009 Nov; 19(22):6459-62. PubMed ID: 19782568
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and structure-activity relationships of 16-modified analogs of 2-methoxyestradiol.
Agoston GE; Shah JH; Lavallee TM; Zhan X; Pribluda VS; Treston AM
Bioorg Med Chem; 2007 Dec; 15(24):7524-37. PubMed ID: 17910916
[TBL] [Abstract][Full Text] [Related]
5. A-ring-substituted estrogen-3-O-sulfamates: potent multitargeted anticancer agents.
Leese MP; Hejaz HA; Mahon MF; Newman SP; Purohit A; Reed MJ; Potter BV
J Med Chem; 2005 Aug; 48(16):5243-56. PubMed ID: 16078843
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and antimitotic activity of novel 2-methoxyestradiol analogs--Part II.
Rao PN; Cessac JW; Boyd JW; Hanson AD; Shah J
Steroids; 2008 Feb; 73(2):158-70. PubMed ID: 18155740
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and antimitotic activity of novel 2-methoxyestradiol analogs. Part III.
Rao PN; Cessac JW; Boyd JW; Hanson AD; Shah J
Steroids; 2008 Feb; 73(2):171-83. PubMed ID: 18155739
[TBL] [Abstract][Full Text] [Related]
8. Estradiol and estrone C-16 derivatives as inhibitors of type 1 17beta-hydroxysteroid dehydrogenase: blocking of ER+ breast cancer cell proliferation induced by estrone.
Laplante Y; Cadot C; Fournier MA; Poirier D
Bioorg Med Chem; 2008 Feb; 16(4):1849-60. PubMed ID: 18035543
[TBL] [Abstract][Full Text] [Related]
9. C6-(N,N-butyl-methyl-heptanamide) derivatives of estrone and estradiol as inhibitors of type 1 17beta-hydroxysteroid dehydrogenase: Chemical synthesis and biological evaluation.
Cadot C; Laplante Y; Kamal F; Luu-The V; Poirier D
Bioorg Med Chem; 2007 Jan; 15(2):714-26. PubMed ID: 17110114
[TBL] [Abstract][Full Text] [Related]
10. Concentration-dependent mitogenic and antiproliferative actions of 2-methoxyestradiol in estrogen receptor-positive human breast cancer cells.
Liu ZJ; Zhu BT
J Steroid Biochem Mol Biol; 2004 Mar; 88(3):265-75. PubMed ID: 15120420
[TBL] [Abstract][Full Text] [Related]
11. p38 Mitogen-activated protein kinases is required for counteraction of 2-methoxyestradiol to estradiol-stimulated cell proliferation and induction of apoptosis in ovarian carcinoma cells via phosphorylation Bcl-2.
Bu SZ; Huang Q; Jiang YM; Min HB; Hou Y; Guo ZY; Wei JF; Wang JW; Ni X; Zheng SS
Apoptosis; 2006 Mar; 11(3):413-25. PubMed ID: 16538384
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and antiproliferative activity of benzyl and phenethyl analogs of makaluvamines.
Shinkre BA; Raisch KP; Fan L; Velu SE
Bioorg Med Chem; 2008 Mar; 16(5):2541-9. PubMed ID: 18093835
[TBL] [Abstract][Full Text] [Related]
13. Anti-cancer activities of novel D-ring modified 2-substituted estrogen-3-O-sulfamates.
Leese MP; Leblond B; Newman SP; Purohit A; Reed MJ; Potter BV
J Steroid Biochem Mol Biol; 2005 Feb; 94(1-3):239-51. PubMed ID: 15862971
[TBL] [Abstract][Full Text] [Related]
14. Modulation of adjuvant arthritis in the rat by 2-methoxyestradiol: an effect independent of an anti-angiogenic action.
Issekutz AC; Sapru K
Int Immunopharmacol; 2008 May; 8(5):708-16. PubMed ID: 18387513
[TBL] [Abstract][Full Text] [Related]
15. Novel 2-methoxyestradiol analogues with antitumor activity.
Tinley TL; Leal RM; Randall-Hlubek DA; Cessac JW; Wilkens LR; Rao PN; Mooberry SL
Cancer Res; 2003 Apr; 63(7):1538-49. PubMed ID: 12670902
[TBL] [Abstract][Full Text] [Related]
16. SAR studies of 2-methoxyestradiol and development of its analogs as probes of anti-tumor mechanisms.
Ho A; Kim YE; Lee H; Cyrus K; Baek SH; Kim KB
Bioorg Med Chem Lett; 2006 Jul; 16(13):3383-7. PubMed ID: 16650989
[TBL] [Abstract][Full Text] [Related]
17. Stilbene-based inhibitors of estrone sulfatase with a dual mode of action in human breast cancer cells.
Walter G; Liebl R; von Angerer E
Arch Pharm (Weinheim); 2004 Dec; 337(12):634-44. PubMed ID: 15597397
[TBL] [Abstract][Full Text] [Related]
18. Selective insensitivity of ZR-75-1 human breast cancer cells to 2-methoxyestradiol: evidence for type II 17beta-hydroxysteroid dehydrogenase as the underlying cause.
Liu ZJ; Lee WJ; Zhu BT
Cancer Res; 2005 Jul; 65(13):5802-11. PubMed ID: 15994956
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of mitochondrial respiration by the anticancer agent 2-methoxyestradiol.
Hagen T; D'Amico G; Quintero M; Palacios-Callender M; Hollis V; Lam F; Moncada S
Biochem Biophys Res Commun; 2004 Sep; 322(3):923-9. PubMed ID: 15336552
[TBL] [Abstract][Full Text] [Related]
20. Safety and pharmacokinetics of intravitreal 2-methoxyestradiol implants in normal rabbit and pharmacodynamics in a rat model of choroidal neovascularization.
Robinson MR; Baffi J; Yuan P; Sung C; Byrnes G; Cox TA; Csaky KG
Exp Eye Res; 2002 Feb; 74(2):309-17. PubMed ID: 11950241
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
