These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

411 related articles for article (PubMed ID: 19762915)

  • 1. Oxidative stress inhibits insulin-like growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK signaling pathways.
    Yin W; Park JI; Loeser RF
    J Biol Chem; 2009 Nov; 284(46):31972-81. PubMed ID: 19762915
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Extracellular nicotinamide phosphoribosyltransferase (NAMPT/visfatin) inhibits insulin-like growth factor-1 signaling and proteoglycan synthesis in human articular chondrocytes.
    Yammani RR; Loeser RF
    Arthritis Res Ther; 2012 Jan; 14(1):R23. PubMed ID: 22289259
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PTEN regulates matrix synthesis in adult human chondrocytes under oxidative stress.
    Iwasa K; Hayashi S; Fujishiro T; Kanzaki N; Hashimoto S; Sakata S; Chinzei N; Nishiyama T; Kuroda R; Kurosaka M
    J Orthop Res; 2014 Feb; 32(2):231-7. PubMed ID: 24155249
    [TBL] [Abstract][Full Text] [Related]  

  • 4. IGF-I stimulation of proteoglycan synthesis by chondrocytes requires activation of the PI 3-kinase pathway but not ERK MAPK.
    Starkman BG; Cravero JD; Delcarlo M; Loeser RF
    Biochem J; 2005 Aug; 389(Pt 3):723-9. PubMed ID: 15801908
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis.
    Cravero JD; Carlson CS; Im HJ; Yammani RR; Long D; Loeser RF
    Arthritis Rheum; 2009 Feb; 60(2):492-500. PubMed ID: 19180501
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insulin-like growth factor 1 inhibits extracellular signal-regulated kinase to promote neuronal survival via the phosphatidylinositol 3-kinase/protein kinase A/c-Raf pathway.
    Subramaniam S; Shahani N; Strelau J; Laliberté C; Brandt R; Kaplan D; Unsicker K
    J Neurosci; 2005 Mar; 25(11):2838-52. PubMed ID: 15772344
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Articular chondrocytes isolated from the knee and ankle joints of human tissue donors demonstrate similar redox-regulated MAP kinase and Akt signaling.
    Collins JA; Arbeeva L; Chubinskaya S; Loeser RF
    Osteoarthritis Cartilage; 2019 Apr; 27(4):703-711. PubMed ID: 30590195
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals.
    Zhang D; Bar-Eli M; Meloche S; Brodt P
    J Biol Chem; 2004 May; 279(19):19683-90. PubMed ID: 14993222
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Microtia patients: Auricular chondrocyte ECM is promoted by CGF through IGF-1 activation of the IGF-1R/PI3K/AKT pathway.
    Chen X; Zhang R; Zhang Q; Xu Z; Xu F; Li D; Li Y
    J Cell Physiol; 2019 Dec; 234(12):21817-21824. PubMed ID: 30471105
    [TBL] [Abstract][Full Text] [Related]  

  • 10. IGF-1 and PDGF-bb suppress IL-1β-induced cartilage degradation through down-regulation of NF-κB signaling: involvement of Src/PI-3K/AKT pathway.
    Montaseri A; Busch F; Mobasheri A; Buhrmann C; Aldinger C; Rad JS; Shakibaei M
    PLoS One; 2011; 6(12):e28663. PubMed ID: 22194879
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rho/ROCK and MEK/ERK activation by transforming growth factor-alpha induces articular cartilage degradation.
    Appleton CT; Usmani SE; Mort JS; Beier F
    Lab Invest; 2010 Jan; 90(1):20-30. PubMed ID: 19823173
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of Phellodendron amurense in protecting human osteoarthritic cartilage and chondrocytes.
    Kim JH; Huh JE; Baek YH; Lee JD; Choi DY; Park DS
    J Ethnopharmacol; 2011 Mar; 134(2):234-42. PubMed ID: 21182922
    [TBL] [Abstract][Full Text] [Related]  

  • 13. IGF-1 regulation of type II collagen and MMP-13 expression in rat endplate chondrocytes via distinct signaling pathways.
    Zhang M; Zhou Q; Liang QQ; Li CG; Holz JD; Tang D; Sheu TJ; Li TF; Shi Q; Wang YJ
    Osteoarthritis Cartilage; 2009 Jan; 17(1):100-6. PubMed ID: 18595745
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Somatostatin inhibits hepatic growth hormone receptor and insulin-like growth factor I mRNA expression by activating the ERK and PI3K signaling pathways.
    Hagemeister AL; Sheridan MA
    Am J Physiol Regul Integr Comp Physiol; 2008 Aug; 295(2):R490-7. PubMed ID: 18495839
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Insulin-like growth factor-I-dependent signal transduction pathways leading to the induction of cell growth and differentiation of human neuroblastoma cell line SH-SY5Y: the roles of MAP kinase pathway and PI 3-kinase pathway.
    Kurihara S; Hakuno F; Takahashi S
    Endocr J; 2000 Dec; 47(6):739-51. PubMed ID: 11228049
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PDGF, bFGF and IGF-I stimulate the proliferation of intervertebral disc cells in vitro via the activation of the ERK and Akt signaling pathways.
    Pratsinis H; Kletsas D
    Eur Spine J; 2007 Nov; 16(11):1858-66. PubMed ID: 17763874
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Benefits of recombinant adeno-associated virus (rAAV)-mediated insulinlike growth factor I (IGF-I) overexpression for the long-term reconstruction of human osteoarthritic cartilage by modulation of the IGF-I axis.
    Weimer A; Madry H; Venkatesan JK; Schmitt G; Frisch J; Wezel A; Jung J; Kohn D; Terwilliger EF; Trippel SB; Cucchiarini M
    Mol Med; 2012 May; 18(1):346-58. PubMed ID: 22160392
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein.
    Mehrhof FB; Müller FU; Bergmann MW; Li P; Wang Y; Schmitz W; Dietz R; von Harsdorf R
    Circulation; 2001 Oct; 104(17):2088-94. PubMed ID: 11673351
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transforming growth factor (TGF)-beta-activated kinase 1 mimics and mediates TGF-beta-induced stimulation of type II collagen synthesis in chondrocytes independent of Col2a1 transcription and Smad3 signaling.
    Qiao B; Padilla SR; Benya PD
    J Biol Chem; 2005 Apr; 280(17):17562-71. PubMed ID: 15743758
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PI3K p110 alpha and p110 beta have differential effects on Akt activation and protection against oxidative stress-induced apoptosis in myoblasts.
    Matheny RW; Adamo ML
    Cell Death Differ; 2010 Apr; 17(4):677-88. PubMed ID: 19834495
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.