224 related articles for article (PubMed ID: 19765986)
21. A strategy of employing aminoheterocycles as amide mimics to identify novel, potent and bioavailable soluble epoxide hydrolase inhibitors.
Shen HC; Ding FX; Deng Q; Xu S; Tong X; Zhang X; Chen Y; Zhou G; Pai LY; Alonso-Galicia M; Roy S; Zhang B; Tata JR; Berger JP; Colletti SL
Bioorg Med Chem Lett; 2009 Oct; 19(19):5716-21. PubMed ID: 19700315
[TBL] [Abstract][Full Text] [Related]
22. A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase.
Gattinoni S; Simone CD; Dallavalle S; Fezza F; Nannei R; Battista N; Minetti P; Quattrociocchi G; Caprioli A; Borsini F; Cabri W; Penco S; Merlini L; Maccarrone M
Bioorg Med Chem Lett; 2010 Aug; 20(15):4406-11. PubMed ID: 20591666
[TBL] [Abstract][Full Text] [Related]
23. Discovery and development of fatty acid amide hydrolase (FAAH) inhibitors.
Seierstad M; Breitenbucher JG
J Med Chem; 2008 Dec; 51(23):7327-43. PubMed ID: 18983142
[No Abstract] [Full Text] [Related]
24. Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amide hydrolase.
Keith JM; Apodaca R; Xiao W; Seierstad M; Pattabiraman K; Wu J; Webb M; Karbarz MJ; Brown S; Wilson S; Scott B; Tham CS; Luo L; Palmer J; Wennerholm M; Chaplan S; Breitenbucher JG
Bioorg Med Chem Lett; 2008 Sep; 18(17):4838-43. PubMed ID: 18693015
[TBL] [Abstract][Full Text] [Related]
25. Fatty acid amide hydrolase inhibitors display broad selectivity and inhibit multiple carboxylesterases as off-targets.
Zhang D; Saraf A; Kolasa T; Bhatia P; Zheng GZ; Patel M; Lannoye GS; Richardson P; Stewart A; Rogers JC; Brioni JD; Surowy CS
Neuropharmacology; 2007 Mar; 52(4):1095-105. PubMed ID: 17217969
[TBL] [Abstract][Full Text] [Related]
26. Cyclohexylcarbamic acid 3'- or 4'-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure-activity relationships, and molecular modeling studies.
Mor M; Rivara S; Lodola A; Plazzi PV; Tarzia G; Duranti A; Tontini A; Piersanti G; Kathuria S; Piomelli D
J Med Chem; 2004 Oct; 47(21):4998-5008. PubMed ID: 15456244
[TBL] [Abstract][Full Text] [Related]
27. 1-Indol-1-yl-propan-2-ones and related heterocyclic compounds as dual inhibitors of cytosolic phospholipase A(2)alpha and fatty acid amide hydrolase.
Forster L; Ludwig J; Kaptur M; Bovens S; Elfringhoff AS; Holtfrerich A; Lehr M
Bioorg Med Chem; 2010 Jan; 18(2):945-52. PubMed ID: 20005725
[TBL] [Abstract][Full Text] [Related]
28. Oxime carbamate--discovery of a series of novel FAAH inhibitors.
Sit SY; Conway CM; Xie K; Bertekap R; Bourin C; Burris KD
Bioorg Med Chem Lett; 2010 Feb; 20(3):1272-7. PubMed ID: 20036536
[TBL] [Abstract][Full Text] [Related]
29. Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 1: identification of 7-azaspiro[3.5]nonane and 1-oxa-8-azaspiro[4.5]decane as lead scaffolds.
Meyers MJ; Long SA; Pelc MJ; Wang JL; Bowen SJ; Walker MC; Schweitzer BA; Madsen HM; Tenbrink RE; McDonald J; Smith SE; Foltin S; Beidler D; Thorarensen A
Bioorg Med Chem Lett; 2011 Nov; 21(21):6538-44. PubMed ID: 21924614
[TBL] [Abstract][Full Text] [Related]
30. Design, synthesis, and in vitro evaluation of carbamate derivatives of 2-benzoxazolyl- and 2-benzothiazolyl-(3-hydroxyphenyl)-methanones as novel fatty acid amide hydrolase inhibitors.
Myllymäki MJ; Saario SM; Kataja AO; Castillo-Melendez JA; Nevalainen T; Juvonen RO; Järvinen T; Koskinen AM
J Med Chem; 2007 Aug; 50(17):4236-42. PubMed ID: 17665899
[TBL] [Abstract][Full Text] [Related]
31. A MBP-FAAH fusion protein as a tool to produce human and rat fatty acid amide hydrolase: expression and pharmacological comparison.
Labar G; Vliet FV; Wouters J; Lambert DM
Amino Acids; 2008 Jan; 34(1):127-33. PubMed ID: 17476568
[TBL] [Abstract][Full Text] [Related]
32. Identification of productive inhibitor binding orientation in fatty acid amide hydrolase (FAAH) by QM/MM mechanistic modelling.
Lodola A; Mor M; Rivara S; Christov C; Tarzia G; Piomelli D; Mulholland AJ
Chem Commun (Camb); 2008 Jan; (2):214-6. PubMed ID: 18092091
[TBL] [Abstract][Full Text] [Related]
33. Macamides and their synthetic analogs: evaluation of in vitro FAAH inhibition.
Wu H; Kelley CJ; Pino-Figueroa A; Vu HD; Maher TJ
Bioorg Med Chem; 2013 Sep; 21(17):5188-97. PubMed ID: 23891163
[TBL] [Abstract][Full Text] [Related]
34. Substituted 2-thioxoimidazolidin-4-ones and imidazolidine-2,4-diones as fatty acid amide hydrolase inhibitors templates.
Muccioli GG; Fazio N; Scriba GK; Poppitz W; Cannata F; Poupaert JH; Wouters J; Lambert DM
J Med Chem; 2006 Jan; 49(1):417-25. PubMed ID: 16392827
[TBL] [Abstract][Full Text] [Related]
35. Application of computational methods to the design of fatty acid amide hydrolase (FAAH) inhibitors based on a carbamic template structure.
Lodola A; Rivara S; Mor M
Adv Protein Chem Struct Biol; 2011; 85():1-26. PubMed ID: 21920320
[TBL] [Abstract][Full Text] [Related]
36. Design, synthesis and evaluation of polar head group containing 2-keto-oxazole inhibitors of FAAH.
Rusch M; Zahov S; Vetter IR; Lehr M; Hedberg C
Bioorg Med Chem; 2012 Jan; 20(2):1100-12. PubMed ID: 22196515
[TBL] [Abstract][Full Text] [Related]
37. Synthesis and preclinical evaluation of [11C-carbonyl]PF-04457845 for neuroimaging of fatty acid amide hydrolase.
Hicks JW; Parkes J; Sadovski O; Tong J; Houle S; Vasdev N; Wilson AA
Nucl Med Biol; 2013 Aug; 40(6):740-6. PubMed ID: 23731552
[TBL] [Abstract][Full Text] [Related]
38. Pyrrolidine-pyrazole ureas as potent and selective inhibitors of 11β-hydroxysteroid-dehydrogenase type 1.
Venier O; Pascal C; Braun A; Namane C; Mougenot P; Crespin O; Pacquet F; Mougenot C; Monseau C; Onofri B; Dadji-Faïhun R; Leger C; Ben-Hassine M; Van-Pham T; Ragot JL; Philippo C; Güssregen S; Engel C; Farjot G; Noah L; Maniani K; Nicolaï E
Bioorg Med Chem Lett; 2011 Apr; 21(8):2244-51. PubMed ID: 21439819
[TBL] [Abstract][Full Text] [Related]
39. The SAR of brain penetration for a series of heteroaryl urea FAAH inhibitors.
Keith JM; Tichenor MS; Apodaca RL; Xiao W; Jones WM; Seierstad M; Pierce JM; Palmer JA; Webb M; Karbarz MJ; Scott BP; Wilson SJ; Wennerholm ML; Rizzolio M; Rynberg R; Chaplan SR; Breitenbucher JG
Bioorg Med Chem Lett; 2016 Jul; 26(13):3109-3114. PubMed ID: 27189675
[TBL] [Abstract][Full Text] [Related]
40. Benzothiophene piperazine and piperidine urea inhibitors of fatty acid amide hydrolase (FAAH).
Johnson DS; Ahn K; Kesten S; Lazerwith SE; Song Y; Morris M; Fay L; Gregory T; Stiff C; Dunbar JB; Liimatta M; Beidler D; Smith S; Nomanbhoy TK; Cravatt BF
Bioorg Med Chem Lett; 2009 May; 19(10):2865-9. PubMed ID: 19386497
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]