These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 19769933)

  • 21. Preliminary in vitro studies on two potent, water-soluble trimethoprim analogues with exceptional species selectivity against dihydrofolate reductase from Pneumocystis carinii and Mycobacterium avium.
    Forsch RA; Queener SF; Rosowsky A
    Bioorg Med Chem Lett; 2004 Apr; 14(7):1811-5. PubMed ID: 15026078
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Novel alleles of Plasmodium falciparum dhfr that confer resistance to chlorcycloguanil.
    Hunt SY; Rezvani BB; Sibley CH
    Mol Biochem Parasitol; 2005 Jan; 139(1):25-32. PubMed ID: 15610816
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Anti-filarial activity of novel formulations of albendazole against experimental brugian filariasis.
    Gaur RL; Dixit S; Sahoo MK; Khanna M; Singh S; Murthy PK
    Parasitology; 2007 Apr; 134(Pt 4):537-44. PubMed ID: 17078904
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Gedunin and photogedunin of Xylocarpus granatum possess antifilarial activity against human lymphatic filarial parasite Brugia malayi in experimental rodent host.
    Misra S; Verma M; Mishra SK; Srivastava S; Lakshmi V; Misra-Bhattacharya S
    Parasitol Res; 2011 Nov; 109(5):1351-60. PubMed ID: 21523424
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Kinetic and molecular properties of the dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant clones of the human malaria parasite Plasmodium falciparum.
    Chen GX; Mueller C; Wendlinger M; Zolg JW
    Mol Pharmacol; 1987 Apr; 31(4):430-7. PubMed ID: 3553892
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Plasmodium falciparum: asparagine mutant at residue 108 of dihydrofolate reductase is an optimal antifolate-resistant single mutant.
    Sirawaraporn W; Yongkiettrakul S; Sirawaraporn R; Yuthavong Y; Santi DV
    Exp Parasitol; 1997 Nov; 87(3):245-52. PubMed ID: 9371090
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Synthesis of 2-sulfanyl-6-methyl-1,4-dihydropyrimidines as a new class of antifilarial agents.
    Singh BK; Mishra M; Saxena N; Yadav GP; Maulik PR; Sahoo MK; Gaur RL; Murthy PK; Tripathi RP
    Eur J Med Chem; 2008 Dec; 43(12):2717-23. PubMed ID: 18339456
    [TBL] [Abstract][Full Text] [Related]  

  • 28. In silico screening against wild-type and mutant Plasmodium falciparum dihydrofolate reductase.
    Fogel GB; Cheung M; Pittman E; Hecht D
    J Mol Graph Model; 2008 Apr; 26(7):1145-52. PubMed ID: 18037315
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Potent 1,3-disubstituted-9H-pyrido[3,4-b]indoles as new lead compounds in antifilarial chemotherapy.
    Srivastava SK; Agarwal A; Chauhan PM; Agarwal SK; Bhaduri AP; Singh SN; Fatima N; Chatterjee RK
    J Med Chem; 1999 May; 42(9):1667-72. PubMed ID: 10229635
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Inhibitors of multiple mutants of Plasmodium falciparum dihydrofolate reductase and their antimalarial activities.
    Kamchonwongpaisan S; Quarrell R; Charoensetakul N; Ponsinet R; Vilaivan T; Vanichtanankul J; Tarnchompoo B; Sirawaraporn W; Lowe G; Yuthavong Y
    J Med Chem; 2004 Jan; 47(3):673-80. PubMed ID: 14736247
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Moxidectin causes adult worm mortality of human lymphatic filarial parasite Brugia malayi in rodent models.
    Verma M; Pathak M; Shahab M; Singh K; Mitra K; Misra-Bhattacharya S
    Folia Parasitol (Praha); 2014 Dec; 61(6):561-70. PubMed ID: 25651699
    [TBL] [Abstract][Full Text] [Related]  

  • 32. An Insight into the Discovery of Potent Antifilarial Leads Against Lymphatic Filariasis.
    Boniface PK; Elizabeth FI
    Curr Drug Targets; 2020; 21(7):657-680. PubMed ID: 31800381
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Sulfonamide chalcones: Synthesis and in vitro exploration for therapeutic potential against Brugia malayi.
    Bahekar SP; Hande SV; Agrawal NR; Chandak HS; Bhoj PS; Goswami K; Reddy MVR
    Eur J Med Chem; 2016 Nov; 124():262-269. PubMed ID: 27592395
    [TBL] [Abstract][Full Text] [Related]  

  • 34. In vitro metabolism of phenoxypropoxybiguanide analogues in human liver microsomes to potent antimalarial dihydrotriazines.
    Shearer TW; Kozar MP; O'Neil MT; Smith PL; Schiehser GA; Jacobus DP; Diaz DS; Yang YS; Milhous WK; Skillman DR
    J Med Chem; 2005 Apr; 48(8):2805-13. PubMed ID: 15828818
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synthesis, biological evaluation and molecular modeling of novel azaspiro dihydrotriazines as influenza virus inhibitors targeting the host factor dihydrofolate reductase (DHFR).
    Francesconi V; Giovannini L; Santucci M; Cichero E; Costi MP; Naesens L; Giordanetto F; Tonelli M
    Eur J Med Chem; 2018 Jul; 155():229-243. PubMed ID: 29886325
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Further studies on 2,4-diamino-5-(2',5'-disubstituted benzyl)pyrimidines as potent and selective inhibitors of dihydrofolate reductases from three major opportunistic pathogens of AIDS.
    Rosowsky A; Forsch RA; Queener SF
    J Med Chem; 2003 Apr; 46(9):1726-36. PubMed ID: 12699390
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: structural basis of antifolate resistance.
    Rastelli G; Sirawaraporn W; Sompornpisut P; Vilaivan T; Kamchonwongpaisan S; Quarrell R; Lowe G; Thebtaranonth Y; Yuthavong Y
    Bioorg Med Chem; 2000 May; 8(5):1117-28. PubMed ID: 10882022
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Search for new prototypes for the chemotherapy of filariasis: a chemotherapeutic and biochemical approach.
    Bajpai P; Verma SK; Katiyar D; Tewari N; Tripathi RP; Bansal I; Saxena JK; Misra-Bhattacharya S
    Parasitol Res; 2005 Apr; 95(6):383-90. PubMed ID: 15739072
    [TBL] [Abstract][Full Text] [Related]  

  • 39. New 2,4-diamino-5-(2',5'-substituted benzyl)pyrimidines as potential drugs against opportunistic infections of AIDS and other immune disorders. Synthesis and species-dependent antifolate activity.
    Rosowsky A; Forsch RA; Sibley CH; Inderlied CB; Queener SF
    J Med Chem; 2004 Mar; 47(6):1475-86. PubMed ID: 14998335
    [TBL] [Abstract][Full Text] [Related]  

  • 40. In Vitro and In Silico Studies of Glycyrrhetinic Acid Derivatives as Anti- Filarial Agents.
    Tyagi R; Verma S; Mishra S; Srivastava M; Alam S; Khan F; Srivastava SK
    Curr Top Med Chem; 2019; 19(14):1191-1200. PubMed ID: 31210109
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.