BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 19770225)

  • 1. Differential activation of mitochondrial apoptotic pathways by vasculotropic amyloid-beta variants in cells composing the cerebral vessel walls.
    Fossati S; Cam J; Meyerson J; Mezhericher E; Romero IA; Couraud PO; Weksler BB; Ghiso J; Rostagno A
    FASEB J; 2010 Jan; 24(1):229-41. PubMed ID: 19770225
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insights into caspase-mediated apoptotic pathways induced by amyloid-β in cerebral microvascular endothelial cells.
    Fossati S; Ghiso J; Rostagno A
    Neurodegener Dis; 2012; 10(1-4):324-8. PubMed ID: 22156599
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cerebral microvascular amyloid beta protein deposition induces vascular degeneration and neuroinflammation in transgenic mice expressing human vasculotropic mutant amyloid beta precursor protein.
    Miao J; Xu F; Davis J; Otte-Höller I; Verbeek MM; Van Nostrand WE
    Am J Pathol; 2005 Aug; 167(2):505-15. PubMed ID: 16049335
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cerebral amyloid angiopathy-linked β-amyloid mutations promote cerebral fibrin deposits via increased binding affinity for fibrinogen.
    Cajamarca SA; Norris EH; van der Weerd L; Strickland S; Ahn HJ
    Proc Natl Acad Sci U S A; 2020 Jun; 117(25):14482-14492. PubMed ID: 32518112
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pathogenic effects of cerebral amyloid angiopathy mutations in the amyloid beta-protein precursor.
    Van Nostrand WE; Melchor JP; Romanov G; Zeigler K; Davis J
    Ann N Y Acad Sci; 2002 Nov; 977():258-65. PubMed ID: 12480759
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Traffic jam at the blood-brain barrier promotes greater accumulation of Alzheimer's disease amyloid-β proteins in the cerebral vasculature.
    Agyare EK; Leonard SR; Curran GL; Yu CC; Lowe VJ; Paravastu AK; Poduslo JF; Kandimalla KK
    Mol Pharm; 2013 May; 10(5):1557-65. PubMed ID: 23249146
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of familial cerebral amyloid angiopathy mutant amyloid beta-protein fibril assembly by myelin basic protein.
    Hoos MD; Ahmed M; Smith SO; Van Nostrand WE
    J Biol Chem; 2007 Mar; 282(13):9952-9961. PubMed ID: 17259179
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Amyloid Beta Oligomers Activate Death Receptors and Mitochondria-Mediated Apoptotic Pathways in Cerebral Vascular Smooth Muscle Cells; Protective Effects of Carbonic Anhydrase Inhibitors.
    Anzovino A; Canepa E; Alves M; Lemon NL; Carare RO; Fossati S
    Cells; 2023 Dec; 12(24):. PubMed ID: 38132159
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hereditary cerebral hemorrhage with amyloidosis-Dutch type.
    Maat-Schieman M; Roos R; van Duinen S
    Neuropathology; 2005 Dec; 25(4):288-97. PubMed ID: 16382777
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amyloid β in hereditary cerebral hemorrhage with amyloidosis-Dutch type.
    Kamp JA; Moursel LG; Haan J; Terwindt GM; Lesnik Oberstein SA; van Duinen SG; van Roon-Mom WM
    Rev Neurosci; 2014; 25(5):641-51. PubMed ID: 24870607
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Anti-Parallel β-Hairpin Structure in Soluble Aβ Oligomers of Aβ40-Dutch and Aβ40-Iowa.
    Fu Z; Van Nostrand WE; Smith SO
    Int J Mol Sci; 2021 Jan; 22(3):. PubMed ID: 33513738
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential contribution of isoaspartate post-translational modifications to the fibrillization and toxic properties of amyloid β and the Asn23 Iowa mutation.
    Fossati S; Todd K; Sotolongo K; Ghiso J; Rostagno A
    Biochem J; 2013 Dec; 456(3):347-60. PubMed ID: 24028142
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Substitutions at codon 22 of Alzheimer's abeta peptide induce diverse conformational changes and apoptotic effects in human cerebral endothelial cells.
    Miravalle L; Tokuda T; Chiarle R; Giaccone G; Bugiani O; Tagliavini F; Frangione B; Ghiso J
    J Biol Chem; 2000 Sep; 275(35):27110-6. PubMed ID: 10821838
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Matrix metalloproteinase 2 (MMP-2) degrades soluble vasculotropic amyloid-beta E22Q and L34V mutants, delaying their toxicity for human brain microvascular endothelial cells.
    Hernandez-Guillamon M; Mawhirt S; Fossati S; Blais S; Pares M; Penalba A; Boada M; Couraud PO; Neubert TA; Montaner J; Ghiso J; Rostagno A
    J Biol Chem; 2010 Aug; 285(35):27144-27158. PubMed ID: 20576603
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitochondrial dysfunction induced by a post-translationally modified amyloid linked to a familial mutation in an alternative model of neurodegeneration.
    Todd K; Fossati S; Ghiso J; Rostagno A
    Biochim Biophys Acta; 2014 Dec; 1842(12 Pt A):2457-67. PubMed ID: 25261792
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tauroursodeoxycholic acid prevents E22Q Alzheimer's Abeta toxicity in human cerebral endothelial cells.
    Viana RJ; Nunes AF; Castro RE; Ramalho RM; Meyerson J; Fossati S; Ghiso J; Rostagno A; Rodrigues CM
    Cell Mol Life Sci; 2009 Mar; 66(6):1094-104. PubMed ID: 19189048
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Vitamin E but not 17beta-estradiol protects against vascular toxicity induced by beta-amyloid wild type and the Dutch amyloid variant.
    Muñoz FJ; Opazo C; Gil-Gómez G; Tapia G; Fernández V; Valverde MA; Inestrosa NC
    J Neurosci; 2002 Apr; 22(8):3081-9. PubMed ID: 11943811
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Familial cerebral amyloid angiopathy related to stroke and dementia.
    Frangione B; Révész T; Vidal R; Holton J; Lashley T; Houlden H; Wood N; Rostagno A; Plant G; Ghiso J
    Amyloid; 2001 Jul; 8 Suppl 1():36-42. PubMed ID: 11676288
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Neurotoxicity and physicochemical properties of Abeta mutant peptides from cerebral amyloid angiopathy: implication for the pathogenesis of cerebral amyloid angiopathy and Alzheimer's disease.
    Murakami K; Irie K; Morimoto A; Ohigashi H; Shindo M; Nagao M; Shimizu T; Shirasawa T
    J Biol Chem; 2003 Nov; 278(46):46179-87. PubMed ID: 12944403
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insulin-degrading enzyme in brain microvessels: proteolysis of amyloid {beta} vasculotropic variants and reduced activity in cerebral amyloid angiopathy.
    Morelli L; Llovera RE; Mathov I; Lue LF; Frangione B; Ghiso J; Castaño EM
    J Biol Chem; 2004 Dec; 279(53):56004-13. PubMed ID: 15489232
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.