141 related articles for article (PubMed ID: 19770486)
1. Discrimination for genotoxic and nongenotoxic carcinogens by gene expression profiling in primary mouse hepatocytes improves with exposure time.
Mathijs K; Brauers KJ; Jennen DG; Boorsma A; van Herwijnen MH; Gottschalk RW; Kleinjans JC; van Delft JH
Toxicol Sci; 2009 Dec; 112(2):374-84. PubMed ID: 19770486
[TBL] [Abstract][Full Text] [Related]
2. Gene expression profiling in primary mouse hepatocytes discriminates true from false-positive genotoxic compounds.
Mathijs K; Brauers KJ; Jennen DG; Lizarraga D; Kleinjans JC; van Delft JH
Mutagenesis; 2010 Nov; 25(6):561-8. PubMed ID: 20650930
[TBL] [Abstract][Full Text] [Related]
3. Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification.
Jennen DG; Magkoufopoulou C; Ketelslegers HB; van Herwijnen MH; Kleinjans JC; van Delft JH
Toxicol Sci; 2010 May; 115(1):66-79. PubMed ID: 20106945
[TBL] [Abstract][Full Text] [Related]
4. Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models.
Doktorova TY; Yildirimman R; Vinken M; Vilardell M; Vanhaecke T; Gmuender H; Bort R; Brolen G; Holmgren G; Li R; Chesne C; van Delft J; Kleinjans J; Castell J; Bjorquist P; Herwig R; Rogiers V
Carcinogenesis; 2013 Jun; 34(6):1393-402. PubMed ID: 23393228
[TBL] [Abstract][Full Text] [Related]
5. Dissecting modes of action of non-genotoxic carcinogens in primary mouse hepatocytes.
Schaap MM; Zwart EP; Wackers PF; Huijskens I; van de Water B; Breit TM; van Steeg H; Jonker MJ; Luijten M
Arch Toxicol; 2012 Nov; 86(11):1717-27. PubMed ID: 22710402
[TBL] [Abstract][Full Text] [Related]
6. Identification of potential biomarkers of genotoxicity and carcinogenicity in L5178Y mouse lymphoma cells by cDNA microarray analysis.
Kim JY; Kwon J; Kim JE; Koh WS; Chung MK; Yoon S; Song CW; Lee M
Environ Mol Mutagen; 2005; 45(1):80-9. PubMed ID: 15612046
[TBL] [Abstract][Full Text] [Related]
7. Comparison of the expression profiles induced by genotoxic and nongenotoxic carcinogens in rat liver.
Ellinger-Ziegelbauer H; Stuart B; Wahle B; Bomann W; Ahr HJ
Mutat Res; 2005 Aug; 575(1-2):61-84. PubMed ID: 15890375
[TBL] [Abstract][Full Text] [Related]
8. Evaluating microRNA profiles reveals discriminative responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytes.
Rieswijk L; Brauers KJ; Coonen ML; van Breda SG; Jennen DG; Kleinjans JC
Mutagenesis; 2015 Nov; 30(6):771-84. PubMed ID: 25976910
[TBL] [Abstract][Full Text] [Related]
9. Deregulation of cancer-related pathways in primary hepatocytes derived from DNA repair-deficient Xpa-/-p53+/- mice upon exposure to benzo[a]pyrene.
van Kesteren PC; Zwart PE; Pennings JL; Gottschalk WH; Kleinjans JC; van Delft JH; van Steeg H; Luijten M
Toxicol Sci; 2011 Sep; 123(1):123-32. PubMed ID: 21715664
[TBL] [Abstract][Full Text] [Related]
10. Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver.
Doktorova TY; Ellinger-Ziegelbauer H; Vinken M; Vanhaecke T; van Delft J; Kleinjans J; Ahr HJ; Rogiers V
Arch Toxicol; 2012 Sep; 86(9):1399-411. PubMed ID: 22484513
[TBL] [Abstract][Full Text] [Related]
11. Finding transcriptomics biomarkers for in vivo identification of (non-)genotoxic carcinogens using wild-type and Xpa/p53 mutant mouse models.
Jonker MJ; Bruning O; van Iterson M; Schaap MM; van der Hoeven TV; Vrieling H; Beems RB; de Vries A; van Steeg H; Breit TM; Luijten M
Carcinogenesis; 2009 Oct; 30(10):1805-12. PubMed ID: 19696161
[TBL] [Abstract][Full Text] [Related]
12. Exploiting microRNA and mRNA profiles generated in vitro from carcinogen-exposed primary mouse hepatocytes for predicting in vivo genotoxicity and carcinogenicity.
Rieswijk L; Brauers KJ; Coonen ML; Jennen DG; van Breda SG; Kleinjans JC
Mutagenesis; 2016 Sep; 31(5):603-15. PubMed ID: 27338304
[TBL] [Abstract][Full Text] [Related]
13. Comparison of supervised clustering methods to discriminate genotoxic from non-genotoxic carcinogens by gene expression profiling.
van Delft JH; van Agen E; van Breda SG; Herwijnen MH; Staal YC; Kleinjans JC
Mutat Res; 2005 Aug; 575(1-2):17-33. PubMed ID: 15924884
[TBL] [Abstract][Full Text] [Related]
14. Identification of early target genes of aflatoxin B1 in human hepatocytes, inter-individual variability and comparison with other genotoxic compounds.
Josse R; Dumont J; Fautrel A; Robin MA; Guillouzo A
Toxicol Appl Pharmacol; 2012 Jan; 258(2):176-87. PubMed ID: 22100608
[TBL] [Abstract][Full Text] [Related]
15. Comparison of basal gene expression profiles and effects of hepatocarcinogens on gene expression in cultured primary human hepatocytes and HepG2 cells.
Harris AJ; Dial SL; Casciano DA
Mutat Res; 2004 May; 549(1-2):79-99. PubMed ID: 15120964
[TBL] [Abstract][Full Text] [Related]
16. In vivo Comet assay on isolated kidney cells to distinguish genotoxic carcinogens from epigenetic carcinogens or cytotoxic compounds.
Nesslany F; Zennouche N; Simar-Meintières S; Talahari I; Nkili-Mboui EN; Marzin D
Mutat Res; 2007 Jun; 630(1-2):28-41. PubMed ID: 17507283
[TBL] [Abstract][Full Text] [Related]
17. A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens.
Schaap MM; Wackers PF; Zwart EP; Huijskens I; Jonker MJ; Hendriks G; Breit TM; van Steeg H; van de Water B; Luijten M
Arch Toxicol; 2015 Dec; 89(12):2413-27. PubMed ID: 25270620
[TBL] [Abstract][Full Text] [Related]
18. Oxidative Stress Mechanisms Do Not Discriminate between Genotoxic and Nongenotoxic Liver Carcinogens.
Deferme L; Wolters J; Claessen S; Briedé J; Kleinjans J
Chem Res Toxicol; 2015 Aug; 28(8):1636-46. PubMed ID: 26198647
[TBL] [Abstract][Full Text] [Related]
19. A comparison of transcriptomic and metabonomic technologies for identifying biomarkers predictive of two-year rodent cancer bioassays.
Thomas RS; O'Connell TM; Pluta L; Wolfinger RD; Yang L; Page TJ
Toxicol Sci; 2007 Mar; 96(1):40-6. PubMed ID: 17114358
[TBL] [Abstract][Full Text] [Related]
20. Sensitive DsRed fluorescence-based reporter cell systems for genotoxicity and oxidative stress assessment.
Hendriks G; Atallah M; Raamsman M; Morolli B; van der Putten H; Jaadar H; Tijdens I; Esveldt-van Lange R; Mullenders L; van de Water B; Vrieling H
Mutat Res; 2011 May; 709-710():49-59. PubMed ID: 21382384
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]