147 related articles for article (PubMed ID: 19773249)
21. Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes.
Hoa NN; Shimizu T; Zhou ZW; Wang ZQ; Deshpande RA; Paull TT; Akter S; Tsuda M; Furuta R; Tsutsui K; Takeda S; Sasanuma H
Mol Cell; 2016 Nov; 64(3):580-592. PubMed ID: 27814490
[TBL] [Abstract][Full Text] [Related]
22. HU-331 is a catalytic inhibitor of topoisomerase IIα.
Regal KM; Mercer SL; Deweese JE
Chem Res Toxicol; 2014 Dec; 27(12):2044-51. PubMed ID: 25409338
[TBL] [Abstract][Full Text] [Related]
23. Inhibition of topoisomerase IIA (Top2α) induces telomeric DNA damage and T cell dysfunction during chronic viral infection.
Dang X; Ogbu SC; Zhao J; Nguyen LNT; Cao D; Nguyen LN; Khanal S; Schank M; Thakuri BKC; Wu XY; Morrison ZD; Zhang J; Li Z; El Gazzar M; Ning S; Wang L; Wang Z; Moorman JP; Yao ZQ
Cell Death Dis; 2020 Mar; 11(3):196. PubMed ID: 32193368
[TBL] [Abstract][Full Text] [Related]
24. Dual targeting of microtubule and topoisomerase II by α-carboline derivative YCH337 for tumor proliferation and growth inhibition.
Yi JM; Zhang XF; Huan XJ; Song SS; Wang W; Tian QT; Sun YM; Chen Y; Ding J; Wang YQ; Yang CH; Miao ZH
Oncotarget; 2015 Apr; 6(11):8960-73. PubMed ID: 25840421
[TBL] [Abstract][Full Text] [Related]
25. Biological characterization of MLN944: a potent DNA binding agent.
Sappal DS; McClendon AK; Fleming JA; Thoroddsen V; Connolly K; Reimer C; Blackman RK; Bulawa CE; Osheroff N; Charlton P; Rudolph-Owen LA
Mol Cancer Ther; 2004 Jan; 3(1):47-58. PubMed ID: 14749475
[TBL] [Abstract][Full Text] [Related]
26. Salvicine, a novel DNA topoisomerase II inhibitor, exerting its effects by trapping enzyme-DNA cleavage complexes.
Meng LH; Zhang JS; Ding J
Biochem Pharmacol; 2001 Sep; 62(6):733-41. PubMed ID: 11551518
[TBL] [Abstract][Full Text] [Related]
27. Ds-echinoside A, a new triterpene glycoside derived from sea cucumber, exhibits antimetastatic activity via the inhibition of NF-κB-dependent MMP-9 and VEGF expressions.
Zhao Q; Liu ZD; Xue Y; Wang JF; Li H; Tang QJ; Wang YM; Dong P; Xue CH
J Zhejiang Univ Sci B; 2011 Jul; 12(7):534-44. PubMed ID: 21726060
[TBL] [Abstract][Full Text] [Related]
28. A cysteine-reactive alkyl hydroquinone modifies topoisomerase IIα, enhances DNA breakage, and induces apoptosis in cancer cells.
Lin TY; Huang CP; Au LC; Chang YW; Hu CY; Lin SB
Chem Res Toxicol; 2012 Nov; 25(11):2340-51. PubMed ID: 23088786
[TBL] [Abstract][Full Text] [Related]
29. The iron chelator Dp44mT causes DNA damage and selective inhibition of topoisomerase IIalpha in breast cancer cells.
Rao VA; Klein SR; Agama KK; Toyoda E; Adachi N; Pommier Y; Shacter EB
Cancer Res; 2009 Feb; 69(3):948-57. PubMed ID: 19176392
[TBL] [Abstract][Full Text] [Related]
30. Novel xanthone-polyamine conjugates as catalytic inhibitors of human topoisomerase IIα.
Minniti E; Byl JAW; Riccardi L; Sissi C; Rosini M; De Vivo M; Minarini A; Osheroff N
Bioorg Med Chem Lett; 2017 Oct; 27(20):4687-4693. PubMed ID: 28919339
[TBL] [Abstract][Full Text] [Related]
31. Effect of TDP2 on the Level of TOP2-DNA Complexes and SUMOylated TOP2-DNA Complexes.
Lee KC; Swan RL; Sondka Z; Padget K; Cowell IG; Austin CA
Int J Mol Sci; 2018 Jul; 19(7):. PubMed ID: 30011940
[TBL] [Abstract][Full Text] [Related]
32. Type II DNA Topoisomerases Cause Spontaneous Double-Strand Breaks in Genomic DNA.
Morimoto S; Tsuda M; Bunch H; Sasanuma H; Austin C; Takeda S
Genes (Basel); 2019 Oct; 10(11):. PubMed ID: 31671674
[TBL] [Abstract][Full Text] [Related]
33. Anthracenedione-methionine conjugates are novel topoisomerase II-targeting anticancer agents with favorable drug resistance profiles.
Lee CH; Hsieh MY; Hsin LW; Chen HC; Lo SC; Fan JR; Chen WR; Chen HW; Chan NL; Li TK
Biochem Pharmacol; 2012 May; 83(9):1208-16. PubMed ID: 22306066
[TBL] [Abstract][Full Text] [Related]
34. DNA topoisomerases as targets for the anticancer drug TAS-103: DNA interactions and topoisomerase catalytic inhibition.
Fortune JM; Velea L; Graves DE; Utsugi T; Yamada Y; Osheroff N
Biochemistry; 1999 Nov; 38(47):15580-6. PubMed ID: 10569942
[TBL] [Abstract][Full Text] [Related]
35. FEN1 participates in repair of the 5'-phosphotyrosyl terminus of DNA single-strand breaks.
Kametani Y; Takahata C; Narita T; Tanaka K; Iwai S; Kuraoka I
Carcinogenesis; 2016 Jan; 37(1):56-62. PubMed ID: 26581212
[TBL] [Abstract][Full Text] [Related]
36. Toward discovering new anti-cancer agents targeting topoisomerase IIα: a facile screening strategy adaptable to high throughput platform.
Lin YS; Huang WC; Chen MS; Hsieh TS
PLoS One; 2014; 9(5):e97008. PubMed ID: 24809695
[TBL] [Abstract][Full Text] [Related]
37. Lycobetaine acts as a selective topoisomerase II beta poison and inhibits the growth of human tumour cells.
Barthelmes HU; Niederberger E; Roth T; Schulte K; Tang WC; Boege F; Fiebig HH; Eisenbrand G; Marko D
Br J Cancer; 2001 Nov; 85(10):1585-91. PubMed ID: 11720449
[TBL] [Abstract][Full Text] [Related]
38. Synthesis, biological evaluation and modeling studies of terphenyl topoisomerase IIα inhibitors as anticancer agents.
Qiu J; Zhao B; Zhong W; Shen Y; Lin H
Eur J Med Chem; 2015 Apr; 94():427-35. PubMed ID: 25800514
[TBL] [Abstract][Full Text] [Related]
39. Androgen Deprivation Followed by Acute Androgen Stimulation Selectively Sensitizes AR-Positive Prostate Cancer Cells to Ionizing Radiation.
Hedayati M; Haffner MC; Coulter JB; Raval RR; Zhang Y; Zhou H; Mian O; Knight EJ; Razavi N; Dalrymple S; Isaacs JT; Santos A; Hales R; Nelson WG; Yegnasubramanian S; DeWeese TL
Clin Cancer Res; 2016 Jul; 22(13):3310-3319. PubMed ID: 26831716
[TBL] [Abstract][Full Text] [Related]
40. Combined treatment with temozolomide and methoxyamine: blocking apurininc/pyrimidinic site repair coupled with targeting topoisomerase IIalpha.
Yan L; Bulgar A; Miao Y; Mahajan V; Donze JR; Gerson SL; Liu L
Clin Cancer Res; 2007 Mar; 13(5):1532-9. PubMed ID: 17332299
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
