BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 19773588)

  • 1. Profiling bioactivity of the ToxCast chemical library using BioMAP primary human cell systems.
    Houck KA; Dix DJ; Judson RS; Kavlock RJ; Yang J; Berg EL
    J Biomol Screen; 2009 Oct; 14(9):1054-66. PubMed ID: 19773588
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ToxCast program for prioritizing toxicity testing of environmental chemicals.
    Dix DJ; Houck KA; Martin MT; Richard AM; Setzer RW; Kavlock RJ
    Toxicol Sci; 2007 Jan; 95(1):5-12. PubMed ID: 16963515
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Profiling the activity of environmental chemicals in prenatal developmental toxicity studies using the U.S. EPA's ToxRefDB.
    Knudsen TB; Martin MT; Kavlock RJ; Judson RS; Dix DJ; Singh AV
    Reprod Toxicol; 2009 Sep; 28(2):209-19. PubMed ID: 19446433
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chemical target and pathway toxicity mechanisms defined in primary human cell systems.
    Berg EL; Yang J; Melrose J; Nguyen D; Privat S; Rosler E; Kunkel EJ; Ekins S
    J Pharmacol Toxicol Methods; 2010; 61(1):3-15. PubMed ID: 19879948
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Computational toxicology as implemented by the U.S. EPA: providing high throughput decision support tools for screening and assessing chemical exposure, hazard and risk.
    Kavlock R; Dix D
    J Toxicol Environ Health B Crit Rev; 2010 Feb; 13(2-4):197-217. PubMed ID: 20574897
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Analysis of Pfizer compounds in EPA's ToxCast chemicals-assay space.
    Shah F; Greene N
    Chem Res Toxicol; 2014 Jan; 27(1):86-98. PubMed ID: 24328225
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Predictive model of rat reproductive toxicity from ToxCast high throughput screening.
    Martin MT; Knudsen TB; Reif DM; Houck KA; Judson RS; Kavlock RJ; Dix DJ
    Biol Reprod; 2011 Aug; 85(2):327-39. PubMed ID: 21565999
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Xenobiotic-metabolizing enzyme and transporter gene expression in primary cultures of human hepatocytes modulated by ToxCast chemicals.
    Rotroff DM; Beam AL; Dix DJ; Farmer A; Freeman KM; Houck KA; Judson RS; LeCluyse EL; Martin MT; Reif DM; Ferguson SS
    J Toxicol Environ Health B Crit Rev; 2010 Feb; 13(2-4):329-46. PubMed ID: 20574906
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program.
    Martin MT; Dix DJ; Judson RS; Kavlock RJ; Reif DM; Richard AM; Rotroff DM; Romanov S; Medvedev A; Poltoratskaya N; Gambarian M; Moeser M; Makarov SS; Houck KA
    Chem Res Toxicol; 2010 Mar; 23(3):578-90. PubMed ID: 20143881
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Predictive models of prenatal developmental toxicity from ToxCast high-throughput screening data.
    Sipes NS; Martin MT; Reif DM; Kleinstreuer NC; Judson RS; Singh AV; Chandler KJ; Dix DJ; Kavlock RJ; Knudsen TB
    Toxicol Sci; 2011 Nov; 124(1):109-27. PubMed ID: 21873373
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Update on EPA's ToxCast program: providing high throughput decision support tools for chemical risk management.
    Kavlock R; Chandler K; Houck K; Hunter S; Judson R; Kleinstreuer N; Knudsen T; Martin M; Padilla S; Reif D; Richard A; Rotroff D; Sipes N; Dix D
    Chem Res Toxicol; 2012 Jul; 25(7):1287-302. PubMed ID: 22519603
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activity profiles of 309 ToxCastâ„¢ chemicals evaluated across 292 biochemical targets.
    Knudsen TB; Houck KA; Sipes NS; Singh AV; Judson RS; Martin MT; Weissman A; Kleinstreuer NC; Mortensen HM; Reif DM; Rabinowitz JR; Setzer RW; Richard AM; Dix DJ; Kavlock RJ
    Toxicology; 2011 Mar; 282(1-2):1-15. PubMed ID: 21251949
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An integrative biology approach for analysis of drug action in models of human vascular inflammation.
    Kunkel EJ; Dea M; Ebens A; Hytopoulos E; Melrose J; Nguyen D; Ota KS; Plavec I; Wang Y; Watson SR; Butcher EC; Berg EL
    FASEB J; 2004 Aug; 18(11):1279-81. PubMed ID: 15208272
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evaluation of high-throughput genotoxicity assays used in profiling the US EPA ToxCast chemicals.
    Knight AW; Little S; Houck K; Dix D; Judson R; Richard A; McCarroll N; Akerman G; Yang C; Birrell L; Walmsley RM
    Regul Toxicol Pharmacol; 2009 Nov; 55(2):188-99. PubMed ID: 19591892
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Building predictive models for mechanism-of-action classification from phenotypic assay data sets.
    Berg EL; Yang J; Polokoff MA
    J Biomol Screen; 2013 Dec; 18(10):1260-9. PubMed ID: 24088371
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Assessing bioactivity-exposure profiles of fruit and vegetable extracts in the BioMAP profiling system.
    Wetmore BA; Clewell RA; Cholewa B; Parks B; Pendse SN; Black MB; Mansouri K; Haider S; Berg EL; Judson RS; Houck KA; Martin M; Clewell HJ; Andersen ME; Thomas RS; McMullen PD
    Toxicol In Vitro; 2019 Feb; 54():41-57. PubMed ID: 30218698
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Predictive models and computational toxicology.
    Knudsen T; Martin M; Chandler K; Kleinstreuer N; Judson R; Sipes N
    Methods Mol Biol; 2013; 947():343-74. PubMed ID: 23138916
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ACToR--Aggregated Computational Toxicology Resource.
    Judson R; Richard A; Dix D; Houck K; Elloumi F; Martin M; Cathey T; Transue TR; Spencer R; Wolf M
    Toxicol Appl Pharmacol; 2008 Nov; 233(1):7-13. PubMed ID: 18671997
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rapid structure-activity and selectivity analysis of kinase inhibitors by BioMAP analysis in complex human primary cell-based models.
    Kunkel EJ; Plavec I; Nguyen D; Melrose J; Rosler ES; Kao LT; Wang Y; Hytopoulos E; Bishop AC; Bateman R; Shokat KM; Butcher EC; Berg EL
    Assay Drug Dev Technol; 2004 Aug; 2(4):431-41. PubMed ID: 15357924
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology.
    Richard AM; Judson RS; Houck KA; Grulke CM; Volarath P; Thillainadarajah I; Yang C; Rathman J; Martin MT; Wambaugh JF; Knudsen TB; Kancherla J; Mansouri K; Patlewicz G; Williams AJ; Little SB; Crofton KM; Thomas RS
    Chem Res Toxicol; 2016 Aug; 29(8):1225-51. PubMed ID: 27367298
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.