BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

282 related articles for article (PubMed ID: 19777057)

  • 1. Human telomerase reverse transcriptase (hTERT) Q169 is essential for telomerase function in vitro and in vivo.
    Wyatt HD; Tsang AR; Lobb DA; Beattie TL
    PLoS One; 2009 Sep; 4(9):e7176. PubMed ID: 19777057
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The N-terminus of hTERT contains a DNA-binding domain and is required for telomerase activity and cellular immortalization.
    Sealey DC; Zheng L; Taboski MA; Cruickshank J; Ikura M; Harrington LA
    Nucleic Acids Res; 2010 Apr; 38(6):2019-35. PubMed ID: 20034955
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of physical and functional anchor site interactions in human telomerase.
    Wyatt HD; Lobb DA; Beattie TL
    Mol Cell Biol; 2007 Apr; 27(8):3226-40. PubMed ID: 17296728
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional regions of human telomerase reverse transcriptase and human telomerase RNA required for telomerase activity and RNA-protein interactions.
    Bachand F; Autexier C
    Mol Cell Biol; 2001 Mar; 21(5):1888-97. PubMed ID: 11238925
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional multimerization of human telomerase requires an RNA interaction domain in the N terminus of the catalytic subunit.
    Moriarty TJ; Huard S; Dupuis S; Autexier C
    Mol Cell Biol; 2002 Feb; 22(4):1253-65. PubMed ID: 11809815
    [TBL] [Abstract][Full Text] [Related]  

  • 6. C-terminal regions of the human telomerase catalytic subunit essential for in vivo enzyme activity.
    Banik SS; Guo C; Smith AC; Margolis SS; Richardson DA; Tirado CA; Counter CM
    Mol Cell Biol; 2002 Sep; 22(17):6234-46. PubMed ID: 12167716
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of interactions between PinX1 and human telomerase subunits hTERT and hTR.
    Banik SS; Counter CM
    J Biol Chem; 2004 Dec; 279(50):51745-8. PubMed ID: 15381700
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An anchor site-type defect in human telomerase that disrupts telomere length maintenance and cellular immortalization.
    Moriarty TJ; Ward RJ; Taboski MA; Autexier C
    Mol Biol Cell; 2005 Jul; 16(7):3152-61. PubMed ID: 15857955
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The C terminus of the human telomerase reverse transcriptase is a determinant of enzyme processivity.
    Huard S; Moriarty TJ; Autexier C
    Nucleic Acids Res; 2003 Jul; 31(14):4059-70. PubMed ID: 12853623
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human telomerase RNA-protein interactions.
    Bachand F; Triki I; Autexier C
    Nucleic Acids Res; 2001 Aug; 29(16):3385-93. PubMed ID: 11504876
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human telomerase reverse transcriptase binds to a pre-organized hTR in vivo exposing its template.
    Zemora G; Handl S; Waldsich C
    Nucleic Acids Res; 2016 Jan; 44(1):413-25. PubMed ID: 26481359
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A physical and functional constituent of telomerase anchor site.
    Lue NF
    J Biol Chem; 2005 Jul; 280(28):26586-91. PubMed ID: 15905172
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RNA binding domain of telomerase reverse transcriptase.
    Lai CK; Mitchell JR; Collins K
    Mol Cell Biol; 2001 Feb; 21(4):990-1000. PubMed ID: 11158287
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A translocation-defective telomerase with low levels of activity and processivity stabilizes short telomeres and confers immortalization.
    D'Souza Y; Chu TW; Autexier C
    Mol Biol Cell; 2013 May; 24(9):1469-79. PubMed ID: 23447707
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding.
    Beattie TL; Zhou W; Robinson MO; Harrington L
    Mol Biol Cell; 2000 Oct; 11(10):3329-40. PubMed ID: 11029039
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of 5' template usage and incorporation of noncognate nucleotides by human telomerase.
    Moriarty TJ; Marie-Egyptienne DT; Autexier C
    RNA; 2005 Sep; 11(9):1448-60. PubMed ID: 16120835
    [TBL] [Abstract][Full Text] [Related]  

  • 17. hTERT mutations associated with idiopathic pulmonary fibrosis affect telomerase activity, telomere length, and cell growth by distinct mechanisms.
    Tsang AR; Wyatt HD; Ting NS; Beattie TL
    Aging Cell; 2012 Jun; 11(3):482-90. PubMed ID: 22364217
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression of hTERT and hTR in cis reconstitutes and active human telomerase ribonucleoprotein.
    Bachand F; Kukolj G; Autexier C
    RNA; 2000 May; 6(5):778-84. PubMed ID: 10836798
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Putative telomere-recruiting domain in the catalytic subunit of human telomerase.
    Armbruster BN; Etheridge KT; Broccoli D; Counter CM
    Mol Cell Biol; 2003 May; 23(9):3237-46. PubMed ID: 12697823
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The active site residue Valine 867 in human telomerase reverse transcriptase influences nucleotide incorporation and fidelity.
    Drosopoulos WC; Prasad VR
    Nucleic Acids Res; 2007; 35(4):1155-68. PubMed ID: 17264120
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.