These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

85 related articles for article (PubMed ID: 19781647)

  • 1. Expression, purification, characterization and crystallization of non- and phosphorylated states of JAK2 and JAK3 kinase domain.
    Hall T; Emmons TL; Chrencik JE; Gormley JA; Weinberg RA; Leone JW; Hirsch JL; Saabye MJ; Schindler JF; Day JE; Williams JM; Kiefer JR; Lightle SA; Harris MS; Guru S; Fischer HD; Tomasselli AG
    Protein Expr Purif; 2010 Jan; 69(1):54-63. PubMed ID: 19781647
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expression, purification, and characterization of TYK-2 kinase domain, a member of the Janus kinase family.
    Korniski B; Wittwer AJ; Emmons TL; Hall T; Brown S; Wrightstone AD; Hirsch JL; Gormley JA; Weinberg RA; Leone JW; Day JE; Chrencik JE; Sommers CD; Fischer HD; Tomasselli AG
    Biochem Biophys Res Commun; 2010 May; 396(2):543-8. PubMed ID: 20435017
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibitors of JAK2 and JAK3: an update on the patent literature 2010 - 2012.
    Dymock BW; See CS
    Expert Opin Ther Pat; 2013 Apr; 23(4):449-501. PubMed ID: 23367873
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.
    Williams NK; Bamert RS; Patel O; Wang C; Walden PM; Wilks AF; Fantino E; Rossjohn J; Lucet IS
    J Mol Biol; 2009 Mar; 387(1):219-32. PubMed ID: 19361440
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Determination of the transphosphorylation sites of Jak2 kinase.
    Matsuda T; Feng J; Witthuhn BA; Sekine Y; Ihle JN
    Biochem Biophys Res Commun; 2004 Dec; 325(2):586-94. PubMed ID: 15530433
    [TBL] [Abstract][Full Text] [Related]  

  • 6. JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response.
    Wang LH; Kirken RA; Erwin RA; Yu CR; Farrar WL
    J Immunol; 1999 Apr; 162(7):3897-904. PubMed ID: 10201908
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Computational analyses of JAK1 kinase domain: subtle changes in the catalytic cleft influence inhibitor specificity.
    Zhang X; Hu Y; Yuan Z
    Biochem Biophys Res Commun; 2008 May; 370(1):72-6. PubMed ID: 18346458
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphorylation of the human Fhit tumor suppressor on tyrosine 114 in Escherichia coli and unexpected steady state kinetics of the phosphorylated forms.
    Garrison PN; Robinson AK; Pekarsky Y; Croce CM; Barnes LD
    Biochemistry; 2005 Apr; 44(16):6286-92. PubMed ID: 15835917
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of Janus kinases by tyrosine phosphorylation inhibitor, Tyrphostin AG-490.
    Rashid S; Bibi N; Parveen Z; Shafique S
    J Biomol Struct Dyn; 2015; 33(11):2368-79. PubMed ID: 26017266
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of JAK2 protein expression by chronic, pulsatile GH administration in vivo: a possible mechanism for ligand enhancement of signal transduction.
    Zhou Y; Wang X; Hadley J; Corey SJ; Vasilatos-Younken R
    Gen Comp Endocrinol; 2005 Nov; 144(2):128-39. PubMed ID: 15993410
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural and thermodynamic characterization of the TYK2 and JAK3 kinase domains in complex with CP-690550 and CMP-6.
    Chrencik JE; Patny A; Leung IK; Korniski B; Emmons TL; Hall T; Weinberg RA; Gormley JA; Williams JM; Day JE; Hirsch JL; Kiefer JR; Leone JW; Fischer HD; Sommers CD; Huang HC; Jacobsen EJ; Tenbrink RE; Tomasselli AG; Benson TE
    J Mol Biol; 2010 Jul; 400(3):413-33. PubMed ID: 20478313
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Physician Education: The Erythropoietin Receptor and Signal Transduction.
    Yoshimura A; Arai K
    Oncologist; 1996; 1(5):337-339. PubMed ID: 10388012
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Specific dephosphorylation of Janus Kinase 2 by protein tyrosine phosphatases.
    Li J; Liu X; Chu H; Fu X; Li T; Hu L; Xing S; Li G; Gu J; Zhao ZJ
    Proteomics; 2015 Jan; 15(1):68-76. PubMed ID: 25354842
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of potent and highly selective thienopyridine Janus kinase 2 inhibitors.
    Schenkel LB; Huang X; Cheng A; Deak HL; Doherty E; Emkey R; Gu Y; Gunaydin H; Kim JL; Lee J; Loberg R; Olivieri P; Pistillo J; Tang J; Wan Q; Wang HL; Wang SW; Wells MC; Wu B; Yu V; Liu L; Geuns-Meyer S
    J Med Chem; 2011 Dec; 54(24):8440-50. PubMed ID: 22087750
    [TBL] [Abstract][Full Text] [Related]  

  • 15. High yield expression of non-phosphorylated protein tyrosine kinases in insect cells.
    Wang L; Foster M; Zhang Y; Tschantz WR; Yang L; Worrall J; Loh C; Xu X
    Protein Expr Purif; 2008 Oct; 61(2):204-11. PubMed ID: 18602836
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2).
    Min X; Ungureanu D; Maxwell S; Hammarén H; Thibault S; Hillert EK; Ayres M; Greenfield B; Eksterowicz J; Gabel C; Walker N; Silvennoinen O; Wang Z
    J Biol Chem; 2015 Nov; 290(45):27261-27270. PubMed ID: 26359499
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of JAK2 activation by Janus homology 2: evidence from molecular dynamics simulations.
    Wan S; Coveney PV
    J Chem Inf Model; 2012 Nov; 52(11):2992-3000. PubMed ID: 23033920
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of a potent Janus kinase 3 inhibitor with high selectivity within the Janus kinase family.
    Thoma G; Nuninger F; Falchetto R; Hermes E; Tavares GA; Vangrevelinghe E; Zerwes HG
    J Med Chem; 2011 Jan; 54(1):284-8. PubMed ID: 21155605
    [TBL] [Abstract][Full Text] [Related]  

  • 19. VX-509 (decernotinib) is a potent and selective janus kinase 3 inhibitor that attenuates inflammation in animal models of autoimmune disease.
    Mahajan S; Hogan JK; Shlyakhter D; Oh L; Salituro FG; Farmer L; Hoock TC
    J Pharmacol Exp Ther; 2015 May; 353(2):405-14. PubMed ID: 25762693
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A receptor-independent, cell-based JAK activation assay for screening for JAK3-specific inhibitors.
    Oh K; Joo KM; Jung YS; Lee J; Kang H; Lee HY; Lee DS
    J Immunol Methods; 2010 Mar; 354(1-2):45-52. PubMed ID: 20138049
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.