These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
133 related articles for article (PubMed ID: 19782440)
1. Known drug space as a metric in exploring the boundaries of drug-like chemical space. Mirza A; Desai R; Reynisson J Eur J Med Chem; 2009 Dec; 44(12):5006-11. PubMed ID: 19782440 [TBL] [Abstract][Full Text] [Related]
2. [Strategy of molecular design of drugs: the unification of macro-properties and micro-structures of a molecule]. Guo ZR Yao Xue Xue Bao; 2008 Mar; 43(3):227-33. PubMed ID: 18630256 [TBL] [Abstract][Full Text] [Related]
3. Characteristics of known drug space. Natural products, their derivatives and synthetic drugs. Bade R; Chan HF; Reynisson J Eur J Med Chem; 2010 Dec; 45(12):5646-52. PubMed ID: 20888084 [TBL] [Abstract][Full Text] [Related]
4. Selection criteria for drug-like compounds. Muegge I Med Res Rev; 2003 May; 23(3):302-21. PubMed ID: 12647312 [TBL] [Abstract][Full Text] [Related]
5. Investigation of the incidence of "undesirable" molecular moieties for high-throughput screening compound libraries in marketed drug compounds. Axerio-Cilies P; Castañeda IP; Mirza A; Reynisson J Eur J Med Chem; 2009 Mar; 44(3):1128-34. PubMed ID: 18692938 [TBL] [Abstract][Full Text] [Related]
6. Development of specific "drug-like property" rules for carboxylate-containing oral drug candidates. Böcker A; Bonneau PR; Hucke O; Jakalian A; Edwards PJ ChemMedChem; 2010 Dec; 5(12):2102-13. PubMed ID: 20979082 [TBL] [Abstract][Full Text] [Related]
7. Drugs in other drugs: a new look at drugs as fragments. Siegel MG; Vieth M Drug Discov Today; 2007 Jan; 12(1-2):71-9. PubMed ID: 17198975 [TBL] [Abstract][Full Text] [Related]
8. [Strategy of molecular drug design: hits, leads and drug candidates]. Guo ZR Yao Xue Xue Bao; 2008 Sep; 43(9):898-904. PubMed ID: 19048779 [TBL] [Abstract][Full Text] [Related]
9. Lead optimization in the nondrug-like space. Zhao H Drug Discov Today; 2011 Feb; 16(3-4):158-63. PubMed ID: 21147254 [TBL] [Abstract][Full Text] [Related]
10. Size estimation of chemical space: how big is it? Drew KL; Baiman H; Khwaounjoo P; Yu B; Reynisson J J Pharm Pharmacol; 2012 Apr; 64(4):490-5. PubMed ID: 22420655 [TBL] [Abstract][Full Text] [Related]
11. Quest for the rings. In silico exploration of ring universe to identify novel bioactive heteroaromatic scaffolds. Ertl P; Jelfs S; Mühlbacher J; Schuffenhauer A; Selzer P J Med Chem; 2006 Jul; 49(15):4568-73. PubMed ID: 16854061 [TBL] [Abstract][Full Text] [Related]
12. Kinase patent space visualization using chemical replacements. Southall NT; Ajay J Med Chem; 2006 Mar; 49(6):2103-9. PubMed ID: 16539399 [TBL] [Abstract][Full Text] [Related]
14. 970 million druglike small molecules for virtual screening in the chemical universe database GDB-13. Blum LC; Reymond JL J Am Chem Soc; 2009 Jul; 131(25):8732-3. PubMed ID: 19505099 [TBL] [Abstract][Full Text] [Related]
15. Bond stability of the "undesirable" heteroatom-heteroatom molecular moieties for high-throughput screening libraries. Yu B; Reynisson J Eur J Med Chem; 2011 Dec; 46(12):5833-7. PubMed ID: 22000918 [TBL] [Abstract][Full Text] [Related]
16. Is chemical synthetic accessibility computationally predictable for drug and lead-like molecules? A comparative assessment between medicinal and computational chemists. Bonnet P Eur J Med Chem; 2012 Aug; 54():679-89. PubMed ID: 22749644 [TBL] [Abstract][Full Text] [Related]
17. Bridging chemical and biological space: "target fishing" using 2D and 3D molecular descriptors. Nettles JH; Jenkins JL; Bender A; Deng Z; Davies JW; Glick M J Med Chem; 2006 Nov; 49(23):6802-10. PubMed ID: 17154510 [TBL] [Abstract][Full Text] [Related]
18. A screening study of ChirBase molecular database to explore the expanded chiral pool derived from the application of chiral chromatography. Piras P; Roussel C J Pharm Biomed Anal; 2008 Apr; 46(5):839-47. PubMed ID: 17942261 [TBL] [Abstract][Full Text] [Related]
20. Analysis of pharmacology data and the prediction of adverse drug reactions and off-target effects from chemical structure. Bender A; Scheiber J; Glick M; Davies JW; Azzaoui K; Hamon J; Urban L; Whitebread S; Jenkins JL ChemMedChem; 2007 Jun; 2(6):861-73. PubMed ID: 17477341 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]