301 related articles for article (PubMed ID: 19787255)
1. PRIMA-1 inhibits growth of breast cancer cells by re-activating mutant p53 protein.
Liang Y; Besch-Williford C; Hyder SM
Int J Oncol; 2009 Nov; 35(5):1015-23. PubMed ID: 19787255
[TBL] [Abstract][Full Text] [Related]
2. Re-activation of the p53 pathway inhibits in vivo and in vitro growth of hormone-dependent human breast cancer cells.
Liang Y; Besch-Williford C; Benakanakere I; Hyder SM
Int J Oncol; 2007 Oct; 31(4):777-84. PubMed ID: 17786308
[TBL] [Abstract][Full Text] [Related]
3. Targeting mutant p53 protein and the tumor vasculature: an effective combination therapy for advanced breast tumors.
Liang Y; Besch-Williford C; Benakanakere I; Thorpe PE; Hyder SM
Breast Cancer Res Treat; 2011 Jan; 125(2):407-20. PubMed ID: 20349129
[TBL] [Abstract][Full Text] [Related]
4. Regression of progestin-accelerated 7,12-dimethylbenz[a]anthracene-induced mammary tumors in Sprague-Dawley rats by p53 reactivation and induction of massive apoptosis: a pilot study.
Benakanakere I; Besch-Williford C; Ellersieck MR; Hyder SM
Endocr Relat Cancer; 2009 Mar; 16(1):85-98. PubMed ID: 19075036
[TBL] [Abstract][Full Text] [Related]
5. PRIMA-1, a mutant p53 reactivator, induces apoptosis and enhances chemotherapeutic cytotoxicity in pancreatic cancer cell lines.
Izetti P; Hautefeuille A; Abujamra AL; de Farias CB; Giacomazzi J; Alemar B; Lenz G; Roesler R; Schwartsmann G; Osvaldt AB; Hainaut P; Ashton-Prolla P
Invest New Drugs; 2014 Oct; 32(5):783-94. PubMed ID: 24838627
[TBL] [Abstract][Full Text] [Related]
6. PRIMA-1 induces apoptosis by inhibiting JNK signaling but promoting the activation of Bax.
Wang T; Lee K; Rehman A; Daoud SS
Biochem Biophys Res Commun; 2007 Jan; 352(1):203-12. PubMed ID: 17113036
[TBL] [Abstract][Full Text] [Related]
7. PRIMA-1(met) radiosensitizes prostate cancer cells independent of their MTp53-status.
Supiot S; Zhao H; Wiman K; Hill RP; Bristow RG
Radiother Oncol; 2008 Mar; 86(3):407-11. PubMed ID: 18237796
[TBL] [Abstract][Full Text] [Related]
8. PRIMA-1 cytotoxicity correlates with nucleolar localization and degradation of mutant p53 in breast cancer cells.
Russo D; Ottaggio L; Penna I; Foggetti G; Fronza G; Inga A; Menichini P
Biochem Biophys Res Commun; 2010 Nov; 402(2):345-50. PubMed ID: 20946886
[TBL] [Abstract][Full Text] [Related]
9. PRIMA-1MET inhibits growth of mouse tumors carrying mutant p53.
Zache N; Lambert JM; Wiman KG; Bykov VJ
Cell Oncol; 2008; 30(5):411-8. PubMed ID: 18791272
[TBL] [Abstract][Full Text] [Related]
10. Selective induction of apoptosis in mutant p53 premalignant and malignant cancer cells by PRIMA-1 through the c-Jun-NH2-kinase pathway.
Li Y; Mao Y; Brandt-Rauf PW; Williams AC; Fine RL
Mol Cancer Ther; 2005 Jun; 4(6):901-9. PubMed ID: 15956247
[TBL] [Abstract][Full Text] [Related]
11. In vitro and in vivo cytotoxic effects of PRIMA-1 on hepatocellular carcinoma cells expressing mutant p53ser249.
Shi H; Lambert JM; Hautefeuille A; Bykov VJ; Wiman KG; Hainaut P; Caron de Fromentel C
Carcinogenesis; 2008 Jul; 29(7):1428-34. PubMed ID: 18048389
[TBL] [Abstract][Full Text] [Related]
12. p53-dependent inhibition of progestin-induced VEGF expression in human breast cancer cells.
Liang Y; Wu J; Stancel GM; Hyder SM
J Steroid Biochem Mol Biol; 2005 Feb; 93(2-5):173-82. PubMed ID: 15860260
[TBL] [Abstract][Full Text] [Related]
13. Expression proteomics to p53 mutation reactivation with PRIMA-1 in breast cancer cells.
Lee K; Wang T; Paszczynski AJ; Daoud SS
Biochem Biophys Res Commun; 2006 Oct; 349(3):1117-24. PubMed ID: 16970918
[TBL] [Abstract][Full Text] [Related]
14. Proteomic identification of heat shock protein 90 as a candidate target for p53 mutation reactivation by PRIMA-1 in breast cancer cells.
Rehman A; Chahal MS; Tang X; Bruce JE; Pommier Y; Daoud SS
Breast Cancer Res; 2005; 7(5):R765-74. PubMed ID: 16168122
[TBL] [Abstract][Full Text] [Related]
15. Novel ovarian cancer maintenance therapy targeted at mortalin and mutant p53.
Ramraj SK; Elayapillai SP; Pelikan RC; Zhao YD; Isingizwe ZR; Kennedy AL; Lightfoot SA; Benbrook DM
Int J Cancer; 2020 Aug; 147(4):1086-1097. PubMed ID: 31845320
[TBL] [Abstract][Full Text] [Related]
16. PRIMA-1 selectively induces global DNA demethylation in p53 mutant-type thyroid cancer cells.
Qiang W; Jin T; Yang Q; Liu W; Liu S; Ji M; He N; Chen C; Shi B; Hou P
J Biomed Nanotechnol; 2014 Jul; 10(7):1249-58. PubMed ID: 24804545
[TBL] [Abstract][Full Text] [Related]
17. PRIMA-1 induces p53-mediated apoptosis by upregulating Noxa in esophageal squamous cell carcinoma with TP53 missense mutation.
Furukawa H; Makino T; Yamasaki M; Tanaka K; Miyazaki Y; Takahashi T; Kurokawa Y; Nakajima K; Takiguchi S; Mori M; Doki Y
Cancer Sci; 2018 Feb; 109(2):412-421. PubMed ID: 29168598
[TBL] [Abstract][Full Text] [Related]
18. PRIMA-1 reactivates mutant p53 by covalent binding to the core domain.
Lambert JM; Gorzov P; Veprintsev DB; Söderqvist M; Segerbäck D; Bergman J; Fersht AR; Hainaut P; Wiman KG; Bykov VJ
Cancer Cell; 2009 May; 15(5):376-88. PubMed ID: 19411067
[TBL] [Abstract][Full Text] [Related]
19. PRIMA-1, a mutant p53 reactivator, restores the sensitivity of TP53 mutant-type thyroid cancer cells to the histone methylation inhibitor 3-Deazaneplanocin A.
Cui B; Yang Q; Guan H; Shi B; Hou P; Ji M
J Clin Endocrinol Metab; 2014 Jun; 99(6):E962-70. PubMed ID: 24512488
[TBL] [Abstract][Full Text] [Related]
20. Antitumor Effects of PRIMA-1 and PRIMA-1
Menichini P; Monti P; Speciale A; Cutrona G; Matis S; Fais F; Taiana E; Neri A; Bomben R; Gentile M; Gattei V; Ferrarini M; Morabito F; Fronza G
Cells; 2021 Jan; 10(1):. PubMed ID: 33430525
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]