BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 19788693)

  • 1. Altered regulation of extrinsic apoptosis pathway in HCV-infected HCC cells enhances susceptibility to mapatumumab-induced apoptosis.
    Zhang X; Frank AC; Gille CM; Daucher M; Kabat J; Becker S; Lempicki RA; Cortez KJ; Polis MA; Subramanian GM; Kottilil S
    Hepatol Res; 2009 Dec; 39(12):1178-89. PubMed ID: 19788693
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human agonistic TRAIL receptor antibodies Mapatumumab and Lexatumumab induce apoptosis in malignant mesothelioma and act synergistically with cisplatin.
    Belyanskaya LL; Marti TM; Hopkins-Donaldson S; Kurtz S; Felley-Bosco E; Stahel RA
    Mol Cancer; 2007 Oct; 6():66. PubMed ID: 17953743
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Augmented antitumor activity against B-cell lymphoma by a combination of monoclonal antibodies targeting TRAIL-R1 and CD20.
    Maddipatla S; Hernandez-Ilizaliturri FJ; Knight J; Czuczman MS
    Clin Cancer Res; 2007 Aug; 13(15 Pt 1):4556-64. PubMed ID: 17671142
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TRAIL-induced apoptosis is preferentially mediated via TRAIL receptor 1 in pancreatic carcinoma cells and profoundly enhanced by XIAP inhibitors.
    Stadel D; Mohr A; Ref C; MacFarlane M; Zhou S; Humphreys R; Bachem M; Cohen G; Möller P; Zwacka RM; Debatin KM; Fulda S
    Clin Cancer Res; 2010 Dec; 16(23):5734-49. PubMed ID: 20940278
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Histone deacetylase inhibitors enhance lexatumumab-induced apoptosis via a p21Cip1-dependent decrease in survivin levels.
    Nawrocki ST; Carew JS; Douglas L; Cleveland JL; Humphreys R; Houghton JA
    Cancer Res; 2007 Jul; 67(14):6987-94. PubMed ID: 17638911
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mapatumumab and lexatumumab induce apoptosis in TRAIL-R1 and TRAIL-R2 antibody-resistant NSCLC cell lines when treated in combination with bortezomib.
    Luster TA; Carrell JA; McCormick K; Sun D; Humphreys R
    Mol Cancer Ther; 2009 Feb; 8(2):292-302. PubMed ID: 19174554
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hepatocyte expression of TRAIL pathway regulators correlates with histopathological and clinical parameters in chronic HCV infection.
    Brost S; Zimmermann A; Koschny R; Sykora J; Stremmel W; Schirmacher P; Walczak H; Ganten TM
    Pathol Res Pract; 2014 Feb; 210(2):83-91. PubMed ID: 24268735
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhanced metastasis suppression by targeting TRAIL receptor 2 in a murine model of triple-negative breast cancer.
    Malin D; Chen F; Schiller C; Koblinski J; Cryns VL
    Clin Cancer Res; 2011 Aug; 17(15):5005-15. PubMed ID: 21653692
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RIP1 protein-dependent assembly of a cytosolic cell death complex is required for inhibitor of apoptosis (IAP) inhibitor-mediated sensitization to lexatumumab-induced apoptosis.
    Basit F; Humphreys R; Fulda S
    J Biol Chem; 2012 Nov; 287(46):38767-77. PubMed ID: 22927431
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Different apoptotic regulation of TRAIL-caspase pathway in HBV- and HCV-related hepatocellular carcinoma.
    Yano Y; Hayashi Y; Nakaji M; Nagano H; Seo Y; Ninomiya T; Yoon S; Wada A; Hirai M; Kim SR; Yokozaki H; Kasuga M
    Int J Mol Med; 2003 Apr; 11(4):499-504. PubMed ID: 12632104
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Partial contribution of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/TRAIL receptor pathway to antitumor effects of interferon-alpha/5-fluorouracil against Hepatocellular Carcinoma.
    Yamamoto T; Nagano H; Sakon M; Wada H; Eguchi H; Kondo M; Damdinsuren B; Ota H; Nakamura M; Wada H; Marubashi S; Miyamoto A; Dono K; Umeshita K; Nakamori S; Yagita H; Monden M
    Clin Cancer Res; 2004 Dec; 10(23):7884-95. PubMed ID: 15585621
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enhancement of lexatumumab-induced apoptosis in human solid cancer cells by Cisplatin in caspase-dependent manner.
    Wu XX; Kakehi Y
    Clin Cancer Res; 2009 Mar; 15(6):2039-47. PubMed ID: 19276256
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bortezomib sensitizes non-Hodgkin's lymphoma cells to apoptosis induced by antibodies to tumor necrosis factor related apoptosis-inducing ligand (TRAIL) receptors TRAIL-R1 and TRAIL-R2.
    Smith MR; Jin F; Joshi I
    Clin Cancer Res; 2007 Sep; 13(18 Pt 2):5528s-5534s. PubMed ID: 17875785
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TRAIL signals to apoptosis in chronic lymphocytic leukaemia cells primarily through TRAIL-R1 whereas cross-linked agonistic TRAIL-R2 antibodies facilitate signalling via TRAIL-R2.
    Natoni A; MacFarlane M; Inoue S; Walewska R; Majid A; Knee D; Stover DR; Dyer MJ; Cohen GM
    Br J Haematol; 2007 Nov; 139(4):568-77. PubMed ID: 17922877
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RIP1 is required for IAP inhibitor-mediated sensitization for TRAIL-induced apoptosis via a RIP1/FADD/caspase-8 cell death complex.
    Abhari BA; Cristofanon S; Kappler R; von Schweinitz D; Humphreys R; Fulda S
    Oncogene; 2013 Jul; 32(27):3263-73. PubMed ID: 22890322
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TRAIL-induced apoptosis of hepatocellular carcinoma cells is augmented by targeted therapies.
    Koehler BC; Urbanik T; Vick B; Boger RJ; Heeger S; Galle PR; Schuchmann M; Schulze-Bergkamen H
    World J Gastroenterol; 2009 Dec; 15(47):5924-35. PubMed ID: 20014456
    [TBL] [Abstract][Full Text] [Related]  

  • 17. COX-2 inhibitors sensitize human hepatocellular carcinoma cells to TRAIL-induced apoptosis.
    Yamanaka Y; Shiraki K; Inoue T; Miyashita K; Fuke H; Yamaguchi Y; Yamamoto N; Ito K; Sugimoto K; Nakano T
    Int J Mol Med; 2006 Jul; 18(1):41-7. PubMed ID: 16786154
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Impact of p53 status on TRAIL-mediated apoptotic and non-apoptotic signaling in cancer cells.
    Willms A; Schittek H; Rahn S; Sosna J; Mert U; Adam D; Trauzold A
    PLoS One; 2019; 14(4):e0214847. PubMed ID: 30947287
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hepatitis C virus core protein modulates TRAIL-mediated apoptosis by enhancing Bid cleavage and activation of mitochondria apoptosis signaling pathway.
    Chou AH; Tsai HF; Wu YY; Hu CY; Hwang LH; Hsu PI; Hsu PN
    J Immunol; 2005 Feb; 174(4):2160-6. PubMed ID: 15699147
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer.
    Trarbach T; Moehler M; Heinemann V; Köhne CH; Przyborek M; Schulz C; Sneller V; Gallant G; Kanzler S
    Br J Cancer; 2010 Feb; 102(3):506-12. PubMed ID: 20068564
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.