BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

298 related articles for article (PubMed ID: 19789328)

  • 1. Identification of a novel small molecule HIF-1alpha translation inhibitor.
    Narita T; Yin S; Gelin CF; Moreno CS; Yepes M; Nicolaou KC; Van Meir EG
    Clin Cancer Res; 2009 Oct; 15(19):6128-36. PubMed ID: 19789328
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibiting the hypoxia response for cancer therapy: the new kid on the block.
    Koh MY; Spivak-Kroizman TR; Powis G
    Clin Cancer Res; 2009 Oct; 15(19):5945-6. PubMed ID: 19789327
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Salidroside ameliorated hypoxia-induced tumorigenesis of BxPC-3 cells via downregulating hypoxia-inducible factor (HIF)-1α and LOXL2.
    Chen X; Kou Y; Lu Y; Pu Y
    J Cell Biochem; 2020 Jan; 121(1):165-173. PubMed ID: 31162697
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway.
    Tan C; de Noronha RG; Roecker AJ; Pyrzynska B; Khwaja F; Zhang Z; Zhang H; Teng Q; Nicholson AC; Giannakakou P; Zhou W; Olson JJ; Pereira MM; Nicolaou KC; Van Meir EG
    Cancer Res; 2005 Jan; 65(2):605-12. PubMed ID: 15695405
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dictamnine promotes apoptosis and inhibits epithelial-mesenchymal transition, migration, invasion and proliferation by downregulating the HIF-1α and Slug signaling pathways.
    Wang JY; Wang Z; Li MY; Zhang Z; Mi C; Zuo HX; Xing Y; Wu YL; Lian LH; Xu GH; Piao LX; Ma J; Jin X
    Chem Biol Interact; 2018 Dec; 296():134-144. PubMed ID: 30266538
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cucurbitacin B inhibits the translational expression of hypoxia-inducible factor-1α.
    Ma J; Zi Jiang Y; Shi H; Mi C; Li J; Xing Nan J; Wu X; Joon Lee J; Jin X
    Eur J Pharmacol; 2014 Jan; 723():46-54. PubMed ID: 24333213
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oltipraz and dithiolethione congeners inhibit hypoxia-inducible factor-1alpha activity through p70 ribosomal S6 kinase-1 inhibition and H2O2-scavenging effect.
    Lee WH; Kim YW; Choi JH; Brooks SC; Lee MO; Kim SG
    Mol Cancer Ther; 2009 Oct; 8(10):2791-802. PubMed ID: 19789218
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cyclin-dependent kinase inhibitor, P276-00, inhibits HIF-1α and induces G2/M arrest under hypoxia in prostate cancer cells.
    Manohar SM; Padgaonkar AA; Jalota-Badhwar A; Rao SV; Joshi KS
    Prostate Cancer Prostatic Dis; 2012 Mar; 15(1):15-27. PubMed ID: 22083267
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of hypoxia-inducible factor-1alpha (HIF-1alpha) protein synthesis by DNA damage inducing agents.
    Lou JJ; Chua YL; Chew EH; Gao J; Bushell M; Hagen T
    PLoS One; 2010 May; 5(5):e10522. PubMed ID: 20479887
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of P3971 an orally efficacious novel anticancer agent targeting HIF-1α and STAT3 pathways.
    Godse P; Kumar P; Yewalkar N; Deore V; Lohar M; Mundada R; Padgaonkar A; Manohar S; Joshi A; Bhatia D; Desai N; Damre A; Bhonde M; Joshi K; Sharma R; Kumar S
    Anticancer Agents Med Chem; 2013 Nov; 13(9):1460-6. PubMed ID: 24102269
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Celastrol inhibits the HIF-1α pathway by inhibition of mTOR/p70S6K/eIF4E and ERK1/2 phosphorylation in human hepatoma cells.
    Ma J; Han LZ; Liang H; Mi C; Shi H; Lee JJ; Jin X
    Oncol Rep; 2014 Jul; 32(1):235-42. PubMed ID: 24859482
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1α via the mTOR/p70S6K/4E-BP1 and MAPK pathways.
    Mi C; Ma J; Wang KS; Zuo HX; Wang Z; Li MY; Piao LX; Xu GH; Li X; Quan ZS; Jin X
    J Ethnopharmacol; 2017 May; 203():27-38. PubMed ID: 28341244
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of hypoxia inducible factor-1α downregulates the expression of epithelial to mesenchymal transition early marker proteins without undermining cell survival in hypoxic lens epithelial cells.
    Cammarata PR; Neelam S; Brooks MM
    Mol Vis; 2015; 21():1024-35. PubMed ID: 26392741
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with cofactors p300/CBP.
    Yin S; Kaluz S; Devi NS; Jabbar AA; de Noronha RG; Mun J; Zhang Z; Boreddy PR; Wang W; Wang Z; Abbruscato T; Chen Z; Olson JJ; Zhang R; Goodman MM; Nicolaou KC; Van Meir EG
    Clin Cancer Res; 2012 Dec; 18(24):6623-33. PubMed ID: 22923450
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hypoxia inducible factor-1α mediates iron uptake which induces inflammatory response in amoeboid microglial cells in developing periventricular white matter through MAP kinase pathway.
    Rathnasamy G; Ling EA; Kaur C
    Neuropharmacology; 2014 Feb; 77():428-40. PubMed ID: 24184387
    [TBL] [Abstract][Full Text] [Related]  

  • 16. BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I.
    Ellinghaus P; Heisler I; Unterschemmann K; Haerter M; Beck H; Greschat S; Ehrmann A; Summer H; Flamme I; Oehme F; Thierauch K; Michels M; Hess-Stumpp H; Ziegelbauer K
    Cancer Med; 2013 Oct; 2(5):611-24. PubMed ID: 24403227
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Perillyl alcohol efficiently scavenges activity of cellular ROS and inhibits the translational expression of hypoxia-inducible factor-1α via mTOR/4E-BP1 signaling pathways.
    Ma J; Li J; Wang KS; Mi C; Piao LX; Xu GH; Li X; Lee JJ; Jin X
    Int Immunopharmacol; 2016 Oct; 39():1-9. PubMed ID: 27394002
    [TBL] [Abstract][Full Text] [Related]  

  • 18. LincRNA-p21 promotes mesenchymal stem cell migration capacity and survival through hypoxic preconditioning.
    Meng SS; Xu XP; Chang W; Lu ZH; Huang LL; Xu JY; Liu L; Qiu HB; Yang Y; Guo FM
    Stem Cell Res Ther; 2018 Oct; 9(1):280. PubMed ID: 30359325
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Altered expression of hypoxia-Inducible factor-1α participates in the epileptogenesis in animal models.
    Li J; Jiang G; Chen Y; Chen L; Li Z; Wang Z; Wang X
    Synapse; 2014 Sep; 68(9):402-9. PubMed ID: 24889205
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis, and target identification of new hypoxia-inducible factor 1 (HIF-1) inhibitors containing 1-alkyl-1H-pyrazole-3-carboxamide moiety.
    Sakai M; Takahashi N; Ikeda H; Furutani Y; Higuchi S; Suzuki T; Dohmae N; Kobayashi S; Harada H; Kojima S; Matsuura T; Hattori A; Kakeya H
    Bioorg Med Chem; 2021 Sep; 46():116375. PubMed ID: 34492592
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.