These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 19791803)

  • 1. Modeling, synthesis and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene).
    Wagner CE; Jurutka PW; Marshall PA; Groy TL; van der Vaart A; Ziller JW; Furmick JK; Graeber ME; Matro E; Miguel BV; Tran IT; Kwon J; Tedeschi JN; Moosavi S; Danishyar A; Philp JS; Khamees RO; Jackson JN; Grupe DK; Badshah SL; Hart JW
    J Med Chem; 2009 Oct; 52(19):5950-66. PubMed ID: 19791803
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modeling, synthesis and biological evaluation of potential retinoid X receptor-selective agonists: novel halogenated analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene).
    Furmick JK; Kaneko I; Walsh AN; Yang J; Bhogal JS; Gray GM; Baso JC; Browder DO; Prentice JL; Montano LA; Huynh CC; Marcus LM; Tsosie DG; Kwon JS; Quezada A; Reyes NM; Lemming B; Saini P; van der Vaart A; Groy TL; Marshall PA; Jurutka PW; Wagner CE
    ChemMedChem; 2012 Sep; 7(9):1551-66. PubMed ID: 22927238
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modeling, synthesis, and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene) and (E)-3-(3-(1,2,3,4-tetrahydro-1,1,4,4,6-pentamethylnaphthalen-7-yl)-4-hydroxyphenyl)acrylic acid (CD3254).
    Jurutka PW; Kaneko I; Yang J; Bhogal JS; Swierski JC; Tabacaru CR; Montano LA; Huynh CC; Jama RA; Mahelona RD; Sarnowski JT; Marcus LM; Quezada A; Lemming B; Tedesco MA; Fischer AJ; Mohamed SA; Ziller JW; Ma N; Gray GM; van der Vaart A; Marshall PA; Wagner CE
    J Med Chem; 2013 Nov; 56(21):8432-54. PubMed ID: 24180745
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Modeling, Synthesis, and Biological Evaluation of Potential Retinoid X Receptor (RXR)-Selective Agonists: Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(5,5,8,8-tetrahydronaphthalen-2-yl)amino)nicotinic Acid (NEt-TMN).
    Heck MC; Wagner CE; Shahani PH; MacNeill M; Grozic A; Darwaiz T; Shimabuku M; Deans DG; Robinson NM; Salama SH; Ziller JW; Ma N; van der Vaart A; Marshall PA; Jurutka PW
    J Med Chem; 2016 Oct; 59(19):8924-8940. PubMed ID: 27592633
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modeling, Synthesis, and Biological Evaluation of Potential Retinoid-X-Receptor (RXR) Selective Agonists: Analogs of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahyro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(4-isobutoxy-3-isopropylphenyl)amino)nicotinic Acid (NEt-4IB).
    Jurutka PW; di Martino O; Reshi S; Mallick S; Sabir ZL; Staniszewski LJP; Warda A; Maiorella EL; Minasian A; Davidson J; Ibrahim SJ; Raban S; Haddad D; Khamisi M; Suban SL; Dawson BJ; Candia R; Ziller JW; Lee MY; Liu C; Liu W; Marshall PA; Welch JS; Wagner CE
    Int J Mol Sci; 2021 Nov; 22(22):. PubMed ID: 34830251
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Methods to Generate an Array of Novel Rexinoids by SAR on a Potent Retinoid X Receptor Agonist: A Case Study with NEt-TMN.
    Wagner CE; Jurutka PW
    Methods Mol Biol; 2019; 2019():109-121. PubMed ID: 31359392
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An Isochroman Analog of CD3254 and Allyl-, Isochroman-Analogs of NEt-TMN Prove to Be More Potent Retinoid-X-Receptor (RXR) Selective Agonists Than Bexarotene.
    Jurutka PW; di Martino O; Reshi S; Mallick S; Sausedo MA; Moen GA; Lee IJ; Ivan DJ; Krall TD; Peoples SJ; Perez A; Tromba L; Le A; Khadka I; Petros R; Savage BM; Salama E; Salama J; Ziller JW; Noh Y; Lee MY; Liu W; Welch JS; Marshall PA; Wagner CE
    Int J Mol Sci; 2022 Dec; 23(24):. PubMed ID: 36555852
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of Bexarotene Analogs for Treating Cutaneous T-Cell Lymphomas.
    Warda A; Staniszewski LJP; Sabir Z; Livingston S; Sausedo M; Reshi S; Ron E; Applegate MT; Haddad D; Khamisi M; Marshall PA; Wagner CE; Jurutka PW
    Cells; 2023 Nov; 12(21):. PubMed ID: 37947652
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells.
    Boehm MF; Zhang L; Zhi L; McClurg MR; Berger E; Wagoner M; Mais DE; Suto CM; Davies JA; Heyman RA
    J Med Chem; 1995 Aug; 38(16):3146-55. PubMed ID: 7636877
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The retinoid X receptor agonist, 9-cis UAB30, inhibits cutaneous T-cell lymphoma proliferation through the SKP2-p27kip1 axis.
    Chou CF; Hsieh YH; Grubbs CJ; Atigadda VR; Mobley JA; Dummer R; Muccio DD; Eto I; Elmets CA; Garvey WT; Chang PL
    J Dermatol Sci; 2018 Jun; 90(3):343-356. PubMed ID: 29599065
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Methods to Assess Activity and Potency of Rexinoids Using Rapid Luciferase-Based Assays: A Case Study with NEt-TMN.
    Jurutka PW; Wagner CE
    Methods Mol Biol; 2019; 2019():95-108. PubMed ID: 31359391
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanism of retinoid X receptor partial agonistic action of 1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)-1H-benzotriazole-5-carboxylic acid and structural development to increase potency.
    Ohsawa F; Yamada S; Yakushiji N; Shinozaki R; Nakayama M; Kawata K; Hagaya M; Kobayashi T; Kohara K; Furusawa Y; Fujiwara C; Ohta Y; Makishima M; Naitou H; Tai A; Yoshikawa Y; Yasui H; Kakuta H
    J Med Chem; 2013 Mar; 56(5):1865-77. PubMed ID: 23391145
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Retinoid X receptor agonist elevation of serum triglycerides in rats by potentiation of retinoic acid receptor agonist induction or by action as single agents.
    Standeven AM; Thacher SM; Yuan YD; Escobar M; Vuligonda V; Beard RL; Chandraratna RA
    Biochem Pharmacol; 2001 Dec; 62(11):1501-9. PubMed ID: 11728386
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A naturally occurring rexinoid, honokiol, can serve as a regulator of various retinoid x receptor heterodimers.
    Kotani H; Tanabe H; Mizukami H; Amagaya S; Inoue M
    Biol Pharm Bull; 2012; 35(1):1-9. PubMed ID: 22223330
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of
    Shibahara O; Watanabe M; Yamada S; Akehi M; Sasaki T; Akahoshi A; Hanada T; Hirano H; Nakatani S; Nishioka H; Takeuchi Y; Kakuta H
    J Med Chem; 2017 Aug; 60(16):7139-7145. PubMed ID: 28753292
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Retinoids increase human apolipoprotein A-11 expression through activation of the retinoid X receptor but not the retinoic acid receptor.
    Vu-Dac N; Schoonjans K; Kosykh V; Dallongeville J; Heyman RA; Staels B; Auwerx J
    Mol Cell Biol; 1996 Jul; 16(7):3350-60. PubMed ID: 8668150
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel silicon-containing analogues of the retinoid agonist bexarotene: syntheses and biological effects on human pluripotent stem cells.
    Bauer JB; Lippert WP; Dörrich S; Tebbe D; Burschka C; Christie VB; Tams DM; Henderson AP; Murray BA; Marder TB; Przyborski SA; Tacke R
    ChemMedChem; 2011 Aug; 6(8):1509-17. PubMed ID: 21726055
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The influence of bexarotene, a selective agonist of the retinoid receptor X (RXR), and tazarotene, a selective agonist of the retinoid acid receptor (RAR), on bone metabolism in rats.
    Nowak B; Matuszewska A; Filipiak J; Nikodem A; Merwid-Ląd A; Pieśniewska M; Fereniec-Gołębiewska L; Kwiatkowska J; Szeląg A
    Adv Med Sci; 2016 Mar; 61(1):85-9. PubMed ID: 26569440
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rexinoids modulate steroid and xenobiotic receptor activity by increasing its protein turnover in a calpain-dependent manner.
    Pettersson F; Hanna N; Lagodich M; Dupéré-Richer D; Couture MC; Choi C; Miller WH
    J Biol Chem; 2008 Aug; 283(32):21945-52. PubMed ID: 18544536
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of novel retinoid X receptor-selective ligands on myeloid leukemia differentiation and proliferation in vitro.
    Kizaki M; Dawson MI; Heyman R; Elster E; Morosetti R; Pakkala S; Chen DL; Ueno H; Chao W; Morikawa M; Ikeda Y; Heber D; Pfahl M; Koeffler HP
    Blood; 1996 Mar; 87(5):1977-84. PubMed ID: 8634447
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.