283 related articles for article (PubMed ID: 19796954)
1. Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials.
Skinner-Adams TS; Stack CM; Trenholme KR; Brown CL; Grembecka J; Lowther J; Mucha A; Drag M; Kafarski P; McGowan S; Whisstock JC; Gardiner DL; Dalton JP
Trends Biochem Sci; 2010 Jan; 35(1):53-61. PubMed ID: 19796954
[TBL] [Abstract][Full Text] [Related]
2. Biochemical and cellular characterisation of the Plasmodium falciparum M1 alanyl aminopeptidase (PfM1AAP) and M17 leucyl aminopeptidase (PfM17LAP).
Mathew R; Wunderlich J; Thivierge K; Cwiklinski K; Dumont C; Tilley L; Rohrbach P; Dalton JP
Sci Rep; 2021 Feb; 11(1):2854. PubMed ID: 33536500
[TBL] [Abstract][Full Text] [Related]
3. Plasmodium falciparum: new molecular targets with potential for antimalarial drug development.
Gardiner DL; Skinner-Adams TS; Brown CL; Andrews KT; Stack CM; McCarthy JS; Dalton JP; Trenholme KR
Expert Rev Anti Infect Ther; 2009 Nov; 7(9):1087-98. PubMed ID: 19883329
[TBL] [Abstract][Full Text] [Related]
4. Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum.
Poreba M; McGowan S; Skinner-Adams TS; Trenholme KR; Gardiner DL; Whisstock JC; To J; Salvesen GS; Dalton JP; Drag M
PLoS One; 2012; 7(2):e31938. PubMed ID: 22359643
[TBL] [Abstract][Full Text] [Related]
5. Selective inhibition of PfA-M1, over PfA-M17, by an amino-benzosuberone derivative blocks malaria parasites development in vitro and in vivo.
Bounaadja L; Schmitt M; Albrecht S; Mouray E; Tarnus C; Florent I
Malar J; 2017 Sep; 16(1):382. PubMed ID: 28934959
[TBL] [Abstract][Full Text] [Related]
6. The A/T-specific DNA alkylating agent adozelesin inhibits Plasmodium falciparum growth in vitro and protects mice against Plasmodium chabaudi adami infection.
Yanow SK; Purcell LA; Spithill TW
Mol Biochem Parasitol; 2006 Jul; 148(1):52-9. PubMed ID: 16597469
[TBL] [Abstract][Full Text] [Related]
7. Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Drinkwater N; Vinh NB; Mistry SN; Bamert RS; Ruggeri C; Holleran JP; Loganathan S; Paiardini A; Charman SA; Powell AK; Avery VM; McGowan S; Scammells PJ
Eur J Med Chem; 2016 Mar; 110():43-64. PubMed ID: 26807544
[TBL] [Abstract][Full Text] [Related]
8. The aminopeptidase inhibitor CHR-2863 is an orally bioavailable inhibitor of murine malaria.
Skinner-Adams TS; Peatey CL; Anderson K; Trenholme KR; Krige D; Brown CL; Stack C; Nsangou DM; Mathews RT; Thivierge K; Dalton JP; Gardiner DL
Antimicrob Agents Chemother; 2012 Jun; 56(6):3244-9. PubMed ID: 22450967
[TBL] [Abstract][Full Text] [Related]
9. Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compounds.
Skinner-Adams TS; Lowther J; Teuscher F; Stack CM; Grembecka J; Mucha A; Kafarski P; Trenholme KR; Dalton JP; Gardiner DL
J Med Chem; 2007 Nov; 50(24):6024-31. PubMed ID: 17960925
[TBL] [Abstract][Full Text] [Related]
10. Helicases - feasible antimalarial drug target for Plasmodium falciparum.
Tuteja R
FEBS J; 2007 Sep; 274(18):4699-704. PubMed ID: 17824956
[TBL] [Abstract][Full Text] [Related]
11. Downstream effects of haemoglobinase inhibition in Plasmodium falciparum-infected erythrocytes.
Naughton JA; Nasizadeh S; Bell A
Mol Biochem Parasitol; 2010 Oct; 173(2):81-7. PubMed ID: 20478341
[TBL] [Abstract][Full Text] [Related]
12. Chemical target validation studies of aminopeptidase in malaria parasites using alpha-aminoalkylphosphonate and phosphonopeptide inhibitors.
Cunningham E; Drag M; Kafarski P; Bell A
Antimicrob Agents Chemother; 2008 Sep; 52(9):3221-8. PubMed ID: 18458130
[TBL] [Abstract][Full Text] [Related]
13. M17 leucine aminopeptidase of the human malaria parasite Plasmodium vivax.
Lee JY; Song SM; Seok JW; Jha BK; Han ET; Song HO; Yu HS; Hong Y; Kong HH; Chung DI
Mol Biochem Parasitol; 2010 Mar; 170(1):45-8. PubMed ID: 19931315
[TBL] [Abstract][Full Text] [Related]
14. Novel selective inhibitors of the zinc plasmodial aminopeptidase PfA-M1 as potential antimalarial agents.
Flipo M; Beghyn T; Leroux V; Florent I; Deprez BP; Deprez-Poulain RF
J Med Chem; 2007 Mar; 50(6):1322-34. PubMed ID: 17326615
[TBL] [Abstract][Full Text] [Related]
15. Aminopeptidases of malaria parasites: new targets for chemotherapy.
Trenholme KR; Brown CL; Skinner-Adams TS; Stack C; Lowther J; To J; Robinson MW; Donnelly SM; Dalton JP; Gardiner DL
Infect Disord Drug Targets; 2010 Jun; 10(3):217-25. PubMed ID: 20334618
[TBL] [Abstract][Full Text] [Related]
16. Inhibitors of Plasmodium falciparum methionine aminopeptidase 1b possess antimalarial activity.
Chen X; Chong CR; Shi L; Yoshimoto T; Sullivan DJ; Liu JO
Proc Natl Acad Sci U S A; 2006 Sep; 103(39):14548-53. PubMed ID: 16983082
[TBL] [Abstract][Full Text] [Related]
17. The M17 leucine aminopeptidase of the malaria parasite Plasmodium falciparum: importance of active site metal ions in the binding of substrates and inhibitors.
Maric S; Donnelly SM; Robinson MW; Skinner-Adams T; Trenholme KR; Gardiner DL; Dalton JP; Stack CM; Lowther J
Biochemistry; 2009 Jun; 48(23):5435-9. PubMed ID: 19408962
[TBL] [Abstract][Full Text] [Related]
18. Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases.
McGowan S; Oellig CA; Birru WA; Caradoc-Davies TT; Stack CM; Lowther J; Skinner-Adams T; Mucha A; Kafarski P; Grembecka J; Trenholme KR; Buckle AM; Gardiner DL; Dalton JP; Whisstock JC
Proc Natl Acad Sci U S A; 2010 Feb; 107(6):2449-54. PubMed ID: 20133789
[TBL] [Abstract][Full Text] [Related]
19. Fumagillin and fumarranol interact with P. falciparum methionine aminopeptidase 2 and inhibit malaria parasite growth in vitro and in vivo.
Chen X; Xie S; Bhat S; Kumar N; Shapiro TA; Liu JO
Chem Biol; 2009 Feb; 16(2):193-202. PubMed ID: 19246010
[TBL] [Abstract][Full Text] [Related]
20. Mapping the substrate specificity of the Plasmodium M1 and M17 aminopeptidases.
Malcolm TR; Swiderska KW; Hayes BK; Webb CT; Drag M; Drinkwater N; McGowan S
Biochem J; 2021 Jul; 478(13):2697-2713. PubMed ID: 34133730
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
