75 related articles for article (PubMed ID: 19800793)
21. Inhibition of the human P2X7 receptor by a novel protein tyrosine kinase antagonist.
Shemon AN; Sluyter R; Stokes L; Manley PW; Wiley JS
Biochem Biophys Res Commun; 2008 Jan; 365(3):515-20. PubMed ID: 17999916
[TBL] [Abstract][Full Text] [Related]
22. Natural products, stylissadines A and B, specific antagonists of the P2X7 receptor, an important inflammatory target.
Buchanan MS; Carroll AR; Addepalli R; Avery VM; Hooper JN; Quinn RJ
J Org Chem; 2007 Mar; 72(7):2309-17. PubMed ID: 17315930
[TBL] [Abstract][Full Text] [Related]
23. Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists.
Baraldi PG; Tabrizi MA; Preti D; Bovero A; Romagnoli R; Fruttarolo F; Zaid NA; Moorman AR; Varani K; Gessi S; Merighi S; Borea PA
J Med Chem; 2004 Mar; 47(6):1434-47. PubMed ID: 14998332
[TBL] [Abstract][Full Text] [Related]
24. Structure-activity relationship studies of pyrimidine-2,4-dione derivatives as potent P2X7 receptor antagonists.
Park JH; Lee GE; Lee SD; Ko H; Kim YC
Eur J Med Chem; 2015 Dec; 106():180-93. PubMed ID: 26547056
[TBL] [Abstract][Full Text] [Related]
25. Novel 1,3-disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) xanthines: high affinity and selective A2B adenosine receptor antagonists.
Kalla RV; Elzein E; Perry T; Li X; Palle V; Varkhedkar V; Gimbel A; Maa T; Zeng D; Zablocki J
J Med Chem; 2006 Jun; 49(12):3682-92. PubMed ID: 16759111
[TBL] [Abstract][Full Text] [Related]
26. 6-Amino-2-mercapto-3H-pyrimidin-4-one derivatives as new candidates for the antagonism at the P2Y12 receptors.
Crepaldi P; Cacciari B; Bonache MC; Spalluto G; Varani K; Borea PA; Kügelgen Iv; Hoffmann K; Pugliano M; Razzari C; Cattaneo M
Bioorg Med Chem; 2009 Jul; 17(13):4612-21. PubMed ID: 19464902
[TBL] [Abstract][Full Text] [Related]
27. Design, synthesis, and inhibition of platelet aggregation for some 1-o-chlorophenyl-1,2,3,4-tetrahydroisoquinoline derivatives.
Yang J; Hua WY; Wang FX; Wang ZY; Wang X
Bioorg Med Chem; 2004 Dec; 12(24):6547-57. PubMed ID: 15556771
[TBL] [Abstract][Full Text] [Related]
28. Discovery of potent and selective adamantane-based small-molecule P2X(7) receptor antagonists/interleukin-1beta inhibitors.
Furber M; Alcaraz L; Bent JE; Beyerbach A; Bowers K; Braddock M; Caffrey MV; Cladingboel D; Collington J; Donald DK; Fagura M; Ince F; Kinchin EC; Laurent C; Lawson M; Luker TJ; Mortimore MM; Pimm AD; Riley RJ; Roberts N; Robertson M; Theaker J; Thorne PV; Weaver R; Webborn P; Willis P
J Med Chem; 2007 Nov; 50(24):5882-5. PubMed ID: 17963373
[TBL] [Abstract][Full Text] [Related]
29. Potent P2X
Ravi RG; Kertesy SB; Dubyak GR; Jacobson KA
Drug Dev Res; 2001 Oct; 54(2):75-87. PubMed ID: 27019545
[TBL] [Abstract][Full Text] [Related]
30. Identification of competitive antagonists of the P2Y1 receptor.
Boyer JL; Romero-Avila T; Schachter JB; Harden TK
Mol Pharmacol; 1996 Nov; 50(5):1323-9. PubMed ID: 8913364
[TBL] [Abstract][Full Text] [Related]
31. Synthesis and SAR of novel 4,5-diarylimidazolines as potent P2X7 receptor antagonists.
Merriman GH; Ma L; Shum P; McGarry D; Volz F; Sabol JS; Gross A; Zhao Z; Rampe D; Wang L; Wirtz-Brugger F; Harris BA; Macdonald D
Bioorg Med Chem Lett; 2005 Jan; 15(2):435-8. PubMed ID: 15603968
[TBL] [Abstract][Full Text] [Related]
32. Design, synthesis, and in vivo SAR of a novel series of pyrazolines as potent selective androgen receptor modulators.
Zhang X; Li X; Allan GF; Sbriscia T; Linton O; Lundeen SG; Sui Z
J Med Chem; 2007 Aug; 50(16):3857-69. PubMed ID: 17636947
[TBL] [Abstract][Full Text] [Related]
33. Decavanadate, a P2X receptor antagonist, and its use to study ligand interactions with P2X7 receptors.
Michel AD; Xing M; Thompson KM; Jones CA; Humphrey PP
Eur J Pharmacol; 2006 Mar; 534(1-3):19-29. PubMed ID: 16487507
[TBL] [Abstract][Full Text] [Related]
34. Subtype specific internalization of P2Y1 and P2Y2 receptors induced by novel adenosine 5'-O-(1-boranotriphosphate) derivatives.
Tulapurkar ME; Laubinger W; Nahum V; Fischer B; Reiser G
Br J Pharmacol; 2004 Jul; 142(5):869-78. PubMed ID: 15197109
[TBL] [Abstract][Full Text] [Related]
35. Characterization of protoberberine analogs employed as novel human P2X7 receptor antagonists.
Lee GE; Lee WG; Lee SY; Lee CR; Park CS; Chang S; Park SG; Song MR; Kim YC
Toxicol Appl Pharmacol; 2011 Apr; 252(2):192-200. PubMed ID: 21320518
[TBL] [Abstract][Full Text] [Related]
36. P2X7 receptor activation induces cell death and CD23 shedding in human RPMI 8226 multiple myeloma cells.
Farrell AW; Gadeock S; Pupovac A; Wang B; Jalilian I; Ranson M; Sluyter R
Biochim Biophys Acta; 2010 Nov; 1800(11):1173-82. PubMed ID: 20647033
[TBL] [Abstract][Full Text] [Related]
37. Synthesis and structure-activity relationship studies of tyrosine-based antagonists at the human P2X7 receptor.
Lee GE; Joshi BV; Chen W; Jeong LS; Moon HR; Jacobson KA; Kim YC
Bioorg Med Chem Lett; 2008 Jan; 18(2):571-5. PubMed ID: 18078749
[TBL] [Abstract][Full Text] [Related]
38. Structure-activity relationships and in vivo activity of (1H-pyrazol-4-yl)acetamide antagonists of the P2X(7) receptor.
Beswick PJ; Billinton A; Chambers LJ; Dean DK; Fonfria E; Gleave RJ; Medhurst SJ; Michel AD; Moses AP; Patel S; Roman SA; Roomans S; Senger S; Stevens AJ; Walter DS
Bioorg Med Chem Lett; 2010 Aug; 20(15):4653-6. PubMed ID: 20579878
[TBL] [Abstract][Full Text] [Related]
39. Discovery and optimization of RO-85, a novel drug-like, potent, and selective P2X3 receptor antagonist.
Brotherton-Pleiss CE; Dillon MP; Ford AP; Gever JR; Carter DS; Gleason SK; Lin CJ; Moore AG; Thompson AW; Villa M; Zhai Y
Bioorg Med Chem Lett; 2010 Feb; 20(3):1031-6. PubMed ID: 20045645
[TBL] [Abstract][Full Text] [Related]
40. From tyrosine to glycine: synthesis and biological activity of potent antagonists of the purinergic P2X7 receptor.
Romagnoli R; Baraldi PG; Carrion MD; Cara CL; Preti D; Cruz-Lopez O; Tabrizi MA; Moorman AR; Gessi S; Fogli E; Sacchetto V; Borea PA
J Med Chem; 2007 Jul; 50(15):3706-15. PubMed ID: 17585854
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]