BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 19802676)

  • 1. Increased p21 expression in chondrocytes of achondroplasic children independently from the presence of the G380R FGFR3 mutation.
    Parafioriti A; del Bianco S; Barisani D; Armiraglio E; Peretti G; Albisetti W
    J Orthop Sci; 2009 Sep; 14(5):623-30. PubMed ID: 19802676
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Overexpression of FGFR3, Stat1, Stat5 and p21Cip1 correlates with phenotypic severity and defective chondrocyte differentiation in FGFR3-related chondrodysplasias.
    Legeai-Mallet L; Benoist-Lasselin C; Munnich A; Bonaventure J
    Bone; 2004 Jan; 34(1):26-36. PubMed ID: 14751560
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype.
    Murakami S; Balmes G; McKinney S; Zhang Z; Givol D; de Crombrugghe B
    Genes Dev; 2004 Feb; 18(3):290-305. PubMed ID: 14871928
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human immortalized chondrocytes carrying heterozygous FGFR3 mutations: an in vitro model to study chondrodysplasias.
    Benoist-Lasselin C; Gibbs L; Heuertz S; Odent T; Munnich A; Legeai-Mallet L
    FEBS Lett; 2007 Jun; 581(14):2593-8. PubMed ID: 17507011
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sustained phosphorylation of mutated FGFR3 is a crucial feature of genetic dwarfism and induces apoptosis in the ATDC5 chondrogenic cell line via PLCgamma-activated STAT1.
    Harada D; Yamanaka Y; Ueda K; Nishimura R; Morishima T; Seino Y; Tanaka H
    Bone; 2007 Aug; 41(2):273-81. PubMed ID: 17561467
    [TBL] [Abstract][Full Text] [Related]  

  • 6. STAT1 and STAT3 do not participate in FGF-mediated growth arrest in chondrocytes.
    Krejci P; Salazar L; Goodridge HS; Kashiwada TA; Schibler MJ; Jelinkova P; Thompson LM; Wilcox WR
    J Cell Sci; 2008 Feb; 121(Pt 3):272-81. PubMed ID: 18198189
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PTHrP rescues ATDC5 cells from apoptosis induced by FGF receptor 3 mutation.
    Yamanaka Y; Tanaka H; Koike M; Nishimura R; Seino Y
    J Bone Miner Res; 2003 Aug; 18(8):1395-403. PubMed ID: 12929929
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insulin-like growth factor-1 rescues the mutated FGF receptor 3 (G380R) expressing ATDC5 cells from apoptosis through phosphatidylinositol 3-kinase and MAPK.
    Koike M; Yamanaka Y; Inoue M; Tanaka H; Nishimura R; Seino Y
    J Bone Miner Res; 2003 Nov; 18(11):2043-51. PubMed ID: 14606518
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tyrosine kinase inhibitor NVP-BGJ398 functionally improves FGFR3-related dwarfism in mouse model.
    Komla-Ebri D; Dambroise E; Kramer I; Benoist-Lasselin C; Kaci N; Le Gall C; Martin L; Busca P; Barbault F; Graus-Porta D; Munnich A; Kneissel M; Di Rocco F; Biosse-Duplan M; Legeai-Mallet L
    J Clin Invest; 2016 May; 126(5):1871-84. PubMed ID: 27064282
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.
    Martin L; Kaci N; Estibals V; Goudin N; Garfa-Traore M; Benoist-Lasselin C; Dambroise E; Legeai-Mallet L
    Hum Mol Genet; 2018 Jan; 27(1):1-13. PubMed ID: 29040558
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of the G375C and G346E achondroplasia mutations on FGFR3 activation.
    He L; Serrano C; Niphadkar N; Shobnam N; Hristova K
    PLoS One; 2012; 7(4):e34808. PubMed ID: 22529939
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Meclozine facilitates proliferation and differentiation of chondrocytes by attenuating abnormally activated FGFR3 signaling in achondroplasia.
    Matsushita M; Kitoh H; Ohkawara B; Mishima K; Kaneko H; Ito M; Masuda A; Ishiguro N; Ohno K
    PLoS One; 2013; 8(12):e81569. PubMed ID: 24324705
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression of fibroblast growth factor receptor-3 (FGFR3), signal transducer and activator of transcription-1, and cyclin-dependent kinase inhibitor p21 during endochondral ossification: differential role of FGFR3 in skeletal development and fracture repair.
    Nakajima A; Shimizu S; Moriya H; Yamazaki M
    Endocrinology; 2003 Oct; 144(10):4659-68. PubMed ID: 12960068
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Delayed bone age due to a dual effect of FGFR3 mutation in Achondroplasia.
    Pannier S; Mugniery E; Jonquoy A; Benoist-Lasselin C; Odent T; Jais JP; Munnich A; Legeai-Mallet L
    Bone; 2010 Nov; 47(5):905-15. PubMed ID: 20673820
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification and in silico characterization of p.G380R substitution in FGFR3, associated with achondroplasia in a non-consanguineous Pakistani family.
    Ajmal M; Mir A; Shoaib M; Malik SA; Nasir M
    Diagn Pathol; 2017 Jul; 12(1):47. PubMed ID: 28679403
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism.
    Su WC; Kitagawa M; Xue N; Xie B; Garofalo S; Cho J; Deng C; Horton WA; Fu XY
    Nature; 1997 Mar; 386(6622):288-92. PubMed ID: 9069288
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sixteen years and counting: the current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasias.
    Foldynova-Trantirkova S; Wilcox WR; Krejci P
    Hum Mutat; 2012 Jan; 33(1):29-41. PubMed ID: 22045636
    [TBL] [Abstract][Full Text] [Related]  

  • 18. FGFR3 mutation causes abnormal membranous ossification in achondroplasia.
    Di Rocco F; Biosse Duplan M; Heuzé Y; Kaci N; Komla-Ebri D; Munnich A; Mugniery E; Benoist-Lasselin C; Legeai-Mallet L
    Hum Mol Genet; 2014 Jun; 23(11):2914-25. PubMed ID: 24419316
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reduced binding of FGF1 to mutant fibroblast growth factor receptor 3.
    Khnykin D; Olsnes S
    Growth Factors; 2006 Jun; 24(2):111-9. PubMed ID: 16801131
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Snail1 is a transcriptional effector of FGFR3 signaling during chondrogenesis and achondroplasias.
    de Frutos CA; Vega S; Manzanares M; Flores JM; Huertas H; Martínez-Frías ML; Nieto MA
    Dev Cell; 2007 Dec; 13(6):872-83. PubMed ID: 18061568
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.