241 related articles for article (PubMed ID: 19805260)
1. A simple ligand that selectively targets CUG trinucleotide repeats and inhibits MBNL protein binding.
Arambula JF; Ramisetty SR; Baranger AM; Zimmerman SC
Proc Natl Acad Sci U S A; 2009 Sep; 106(38):16068-73. PubMed ID: 19805260
[TBL] [Abstract][Full Text] [Related]
2. Novel proteins with binding specificity for DNA CTG repeats and RNA CUG repeats: implications for myotonic dystrophy.
Timchenko LT; Timchenko NA; Caskey CT; Roberts R
Hum Mol Genet; 1996 Jan; 5(1):115-21. PubMed ID: 8789448
[TBL] [Abstract][Full Text] [Related]
3. MBNL binds similar RNA structures in the CUG repeats of myotonic dystrophy and its pre-mRNA substrate cardiac troponin T.
Warf MB; Berglund JA
RNA; 2007 Dec; 13(12):2238-51. PubMed ID: 17942744
[TBL] [Abstract][Full Text] [Related]
4. Short antisense-locked nucleic acids (all-LNAs) correct alternative splicing abnormalities in myotonic dystrophy.
Wojtkowiak-Szlachcic A; Taylor K; Stepniak-Konieczna E; Sznajder LJ; Mykowska A; Sroka J; Thornton CA; Sobczak K
Nucleic Acids Res; 2015 Mar; 43(6):3318-31. PubMed ID: 25753670
[TBL] [Abstract][Full Text] [Related]
5. A Ligand That Targets CUG Trinucleotide Repeats.
Li J; Matsumoto J; Bai LP; Murata A; Dohno C; Nakatani K
Chemistry; 2016 Oct; 22(42):14881-14889. PubMed ID: 27573860
[TBL] [Abstract][Full Text] [Related]
6. Utilizing the GAAA tetraloop/receptor to facilitate crystal packing and determination of the structure of a CUG RNA helix.
Coonrod LA; Lohman JR; Berglund JA
Biochemistry; 2012 Oct; 51(42):8330-7. PubMed ID: 23025897
[TBL] [Abstract][Full Text] [Related]
7. Cardiac elav-type RNA-binding protein (ETR-3) binds to RNA CUG repeats expanded in myotonic dystrophy.
Lu X; Timchenko NA; Timchenko LT
Hum Mol Genet; 1999 Jan; 8(1):53-60. PubMed ID: 9887331
[TBL] [Abstract][Full Text] [Related]
8. Structural Basis for Targeting T:T Mismatch with Triaminotriazine-Acridine Conjugate Induces a U-Shaped Head-to-Head Four-Way Junction in CTG Repeat DNA.
Chien CM; Wu PC; Satange R; Chang CC; Lai ZL; Hagler LD; Zimmerman SC; Hou MH
J Am Chem Soc; 2020 Jun; 142(25):11165-11172. PubMed ID: 32478511
[TBL] [Abstract][Full Text] [Related]
9. Single-molecule study of the CUG repeat-MBNL1 interaction and its inhibition by small molecules.
Haghighat Jahromi A; Honda M; Zimmerman SC; Spies M
Nucleic Acids Res; 2013 Jul; 41(13):6687-97. PubMed ID: 23661680
[TBL] [Abstract][Full Text] [Related]
10. Developing bivalent ligands to target CUG triplet repeats, the causative agent of myotonic dystrophy type 1.
Jahromi AH; Fu Y; Miller KA; Nguyen L; Luu LM; Baranger AM; Zimmerman SC
J Med Chem; 2013 Dec; 56(23):9471-9481. PubMed ID: 24188018
[TBL] [Abstract][Full Text] [Related]
11. Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse model.
Angelbello AJ; Rzuczek SG; Mckee KK; Chen JL; Olafson H; Cameron MD; Moss WN; Wang ET; Disney MD
Proc Natl Acad Sci U S A; 2019 Apr; 116(16):7799-7804. PubMed ID: 30926669
[TBL] [Abstract][Full Text] [Related]
12. A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels.
Reddy K; Jenquin JR; McConnell OL; Cleary JD; Richardson JI; Pinto BS; Haerle MC; Delgado E; Planco L; Nakamori M; Wang ET; Berglund JA
Proc Natl Acad Sci U S A; 2019 Oct; 116(42):20991-21000. PubMed ID: 31570586
[TBL] [Abstract][Full Text] [Related]
13. MBNL1-RNA recognition: contributions of MBNL1 sequence and RNA conformation.
Fu Y; Ramisetty SR; Hussain N; Baranger AM
Chembiochem; 2012 Jan; 13(1):112-9. PubMed ID: 22106026
[TBL] [Abstract][Full Text] [Related]
14. Colocalization of muscleblind with RNA foci is separable from mis-regulation of alternative splicing in myotonic dystrophy.
Ho TH; Savkur RS; Poulos MG; Mancini MA; Swanson MS; Cooper TA
J Cell Sci; 2005 Jul; 118(Pt 13):2923-33. PubMed ID: 15961406
[TBL] [Abstract][Full Text] [Related]
15. Rationally designed small molecules that target both the DNA and RNA causing myotonic dystrophy type 1.
Nguyen L; Luu LM; Peng S; Serrano JF; Chan HY; Zimmerman SC
J Am Chem Soc; 2015 Nov; 137(44):14180-9. PubMed ID: 26473464
[TBL] [Abstract][Full Text] [Related]
16. Investigating the binding mode of an inhibitor of the MBNL1·RNA complex in myotonic dystrophy type 1 (DM1) leads to the unexpected discovery of a DNA-selective binder.
Wong CH; Richardson SL; Ho YJ; Lucas AM; Tuccinardi T; Baranger AM; Zimmerman SC
Chembiochem; 2012 Nov; 13(17):2505-9. PubMed ID: 23097190
[No Abstract] [Full Text] [Related]
17. Furamidine Rescues Myotonic Dystrophy Type I Associated Mis-Splicing through Multiple Mechanisms.
Jenquin JR; Coonrod LA; Silverglate QA; Pellitier NA; Hale MA; Xia G; Nakamori M; Berglund JA
ACS Chem Biol; 2018 Sep; 13(9):2708-2718. PubMed ID: 30118588
[TBL] [Abstract][Full Text] [Related]
18. RNA CUG repeats sequester CUGBP1 and alter protein levels and activity of CUGBP1.
Timchenko NA; Cai ZJ; Welm AL; Reddy S; Ashizawa T; Timchenko LT
J Biol Chem; 2001 Mar; 276(11):7820-6. PubMed ID: 11124939
[TBL] [Abstract][Full Text] [Related]
19. Defined D-hexapeptides bind CUG repeats and rescue phenotypes of myotonic dystrophy myotubes in a Drosophila model of the disease.
Rapisarda A; Bargiela A; Llamusi B; Pont I; Estrada-Tejedor R; Garcia-España E; Artero R; Perez-Alonso M
Sci Rep; 2021 Sep; 11(1):19417. PubMed ID: 34593893
[TBL] [Abstract][Full Text] [Related]
20. Visualization of double-stranded RNAs from the myotonic dystrophy protein kinase gene and interactions with CUG-binding protein.
Michalowski S; Miller JW; Urbinati CR; Paliouras M; Swanson MS; Griffith J
Nucleic Acids Res; 1999 Sep; 27(17):3534-42. PubMed ID: 10446244
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
