These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 19815556)

  • 1. Down-regulation of seladin-1 increases BACE1 levels and activity through enhanced GGA3 depletion during apoptosis.
    Sarajärvi T; Haapasalo A; Viswanathan J; Mäkinen P; Laitinen M; Soininen H; Hiltunen M
    J Biol Chem; 2009 Dec; 284(49):34433-43. PubMed ID: 19815556
    [TBL] [Abstract][Full Text] [Related]  

  • 2. BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice.
    Kim W; Ma L; Lomoio S; Willen R; Lombardo S; Dong J; Haydon PG; Tesco G
    Mol Neurodegener; 2018 Feb; 13(1):6. PubMed ID: 29391027
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1).
    von Einem B; Wahler A; Schips T; Serrano-Pozo A; Proepper C; Boeckers TM; Rueck A; Wirth T; Hyman BT; Danzer KM; Thal DR; von Arnim CA
    PLoS One; 2015; 10(6):e0129047. PubMed ID: 26053850
    [TBL] [Abstract][Full Text] [Related]  

  • 4. GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production.
    Herskowitz JH; Offe K; Deshpande A; Kahn RA; Levey AI; Lah JJ
    Mol Biol Cell; 2012 Jul; 23(14):2645-57. PubMed ID: 22621900
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mild oxidative stress induces redistribution of BACE1 in non-apoptotic conditions and promotes the amyloidogenic processing of Alzheimer's disease amyloid precursor protein.
    Tan JL; Li QX; Ciccotosto GD; Crouch PJ; Culvenor JG; White AR; Evin G
    PLoS One; 2013; 8(4):e61246. PubMed ID: 23613819
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ubiquitin regulates GGA3-mediated degradation of BACE1.
    Kang EL; Cameron AN; Piazza F; Walker KR; Tesco G
    J Biol Chem; 2010 Jul; 285(31):24108-19. PubMed ID: 20484053
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity.
    Tesco G; Koh YH; Kang EL; Cameron AN; Das S; Sena-Esteves M; Hiltunen M; Yang SH; Zhong Z; Shen Y; Simpkins JW; Tanzi RE
    Neuron; 2007 Jun; 54(5):721-37. PubMed ID: 17553422
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Elucidation of the BACE1 regulating factor GGA3 in Alzheimer's disease.
    Natunen T; Parrado AR; Helisalmi S; Pursiheimo JP; Sarajärvi T; Mäkinen P; Kurkinen KM; Mullin K; Alafuzoff I; Haapasalo A; Bertram L; Soininen H; Tanzi RE; Hiltunen M
    J Alzheimers Dis; 2013; 37(1):217-32. PubMed ID: 23970038
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
    Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
    Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of seladin-1/DHCR24 in cholesterol biosynthesis, APP processing and Abeta generation in vivo.
    Crameri A; Biondi E; Kuehnle K; Lütjohann D; Thelen KM; Perga S; Dotti CG; Nitsch RM; Ledesma MD; Mohajeri MH
    EMBO J; 2006 Jan; 25(2):432-43. PubMed ID: 16407971
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Endosome-associated Deubiquitinating Enzyme USP8 Regulates BACE1 Enzyme Ubiquitination and Degradation.
    Yeates EF; Tesco G
    J Biol Chem; 2016 Jul; 291(30):15753-66. PubMed ID: 27302062
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SEPT8 modulates β-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.
    Kurkinen KM; Marttinen M; Turner L; Natunen T; Mäkinen P; Haapalinna F; Sarajärvi T; Gabbouj S; Kurki M; Paananen J; Koivisto AM; Rauramaa T; Leinonen V; Tanila H; Soininen H; Lucas FR; Haapasalo A; Hiltunen M
    J Cell Sci; 2016 Jun; 129(11):2224-38. PubMed ID: 27084579
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The influence of inhibiting or stimulating the expression of the α3 subunit of the nicotinic receptor in SH-SY5Y cells on levels of amyloid-β peptide and β-secretase.
    Qi XL; Zhang XL; Ou-Yang K; Shan KR; Guan ZZ
    Neurochem Int; 2013 Jan; 62(1):79-83. PubMed ID: 23201341
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The human DIMINUTO/DWARF1 homolog seladin-1 confers resistance to Alzheimer's disease-associated neurodegeneration and oxidative stress.
    Greeve I; Hermans-Borgmeyer I; Brellinger C; Kasper D; Gomez-Isla T; Behl C; Levkau B; Nitsch RM
    J Neurosci; 2000 Oct; 20(19):7345-52. PubMed ID: 11007892
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genetic Deletion of the Clathrin Adaptor GGA3 Reduces Anxiety and Alters GABAergic Transmission.
    Walker KR; Modgil A; Albrecht D; Lomoio S; Haydon PG; Moss SJ; Tesco G
    PLoS One; 2016; 11(5):e0155799. PubMed ID: 27192432
    [TBL] [Abstract][Full Text] [Related]  

  • 16.
    Lomoio S; Willen R; Kim W; Ho KZ; Robinson EK; Prokopenko D; Kennedy ME; Tanzi RE; Tesco G
    Sci Transl Med; 2020 Nov; 12(570):. PubMed ID: 33208500
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
    Ye X; Feng T; Tammineni P; Chang Q; Jeong YY; Margolis DJ; Cai H; Kusnecov A; Cai Q
    J Neurosci; 2017 Mar; 37(10):2639-2655. PubMed ID: 28159908
    [TBL] [Abstract][Full Text] [Related]  

  • 18. GGA1 is expressed in the human brain and affects the generation of amyloid beta-peptide.
    Wahle T; Thal DR; Sastre M; Rentmeister A; Bogdanovic N; Famulok M; Heneka MT; Walter J
    J Neurosci; 2006 Dec; 26(49):12838-46. PubMed ID: 17151287
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Long-term oral melatonin alleviates memory deficits, reduces amyloid-β deposition associated with downregulation of BACE1 and mitophagy in APP/PS1 transgenic mice.
    Sun C; Qiu X; Wang Y; Liu J; Li Q; Jiang H; Li S; Song C
    Neurosci Lett; 2020 Sep; 735():135192. PubMed ID: 32619650
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Decreased expression of GGA3 protein in Alzheimer's disease frontal cortex and increased co-distribution of BACE with the amyloid precursor protein.
    Santosa C; Rasche S; Barakat A; Bellingham SA; Ho M; Tan J; Hill AF; Masters CL; McLean C; Evin G
    Neurobiol Dis; 2011 Jul; 43(1):176-83. PubMed ID: 21440067
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.