BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

355 related articles for article (PubMed ID: 19818716)

  • 1. KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta.
    Lee DF; Kuo HP; Liu M; Chou CK; Xia W; Du Y; Shen J; Chen CT; Huo L; Hsu MC; Li CW; Ding Q; Liao TL; Lai CC; Lin AC; Chang YH; Tsai SF; Li LY; Hung MC
    Mol Cell; 2009 Oct; 36(1):131-40. PubMed ID: 19818716
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetic disruption of KEAP1/CUL3 E3 ubiquitin ligase complex components is a key mechanism of NF-kappaB pathway activation in lung cancer.
    Thu KL; Pikor LA; Chari R; Wilson IM; Macaulay CE; English JC; Tsao MS; Gazdar AF; Lam S; Lam WL; Lockwood WW
    J Thorac Oncol; 2011 Sep; 6(9):1521-9. PubMed ID: 21795997
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Suppression of NF-kappaB signaling by KEAP1 regulation of IKKbeta activity through autophagic degradation and inhibition of phosphorylation.
    Kim JE; You DJ; Lee C; Ahn C; Seong JY; Hwang JI
    Cell Signal; 2010 Nov; 22(11):1645-54. PubMed ID: 20600852
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Marburg Virus VP24 Protein Relieves Suppression of the NF-κB Pathway Through Interaction With Kelch-like ECH-Associated Protein 1.
    Edwards MR; Basler CF
    J Infect Dis; 2015 Oct; 212 Suppl 2(Suppl 2):S154-9. PubMed ID: 25926686
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Keap1 regulates inflammatory signaling in Mycobacterium avium-infected human macrophages.
    Awuh JA; Haug M; Mildenberger J; Marstad A; Do CP; Louet C; Stenvik J; Steigedal M; Damås JK; Halaas Ø; Flo TH
    Proc Natl Acad Sci U S A; 2015 Aug; 112(31):E4272-80. PubMed ID: 26195781
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insight into the intermolecular recognition mechanism between Keap1 and IKKβ combining homology modelling, protein-protein docking, molecular dynamics simulations and virtual alanine mutation.
    Jiang ZY; Chu HX; Xi MY; Yang TT; Jia JM; Huang JJ; Guo XK; Zhang XJ; You QD; Sun HP
    PLoS One; 2013; 8(9):e75076. PubMed ID: 24066166
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Keap1 silencing boosts lipopolysaccharide-induced transcription of interleukin 6 via activation of nuclear factor κB in macrophages.
    Lv P; Xue P; Dong J; Peng H; Clewell R; Wang A; Wang Y; Peng S; Qu W; Zhang Q; Andersen ME; Pi J
    Toxicol Appl Pharmacol; 2013 Nov; 272(3):697-702. PubMed ID: 23906629
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.
    Furukawa M; Xiong Y
    Mol Cell Biol; 2005 Jan; 25(1):162-71. PubMed ID: 15601839
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kelch-like Protein 21 (KLHL21) Targets IκB Kinase-β to Regulate Nuclear Factor κ-Light Chain Enhancer of Activated B Cells (NF-κB) Signaling Negatively.
    Mei ZZ; Chen XY; Hu SW; Wang N; Ou XL; Wang J; Luo HH; Liu J; Jiang Y
    J Biol Chem; 2016 Aug; 291(35):18176-89. PubMed ID: 27387502
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Unique pattern of component gene disruption in the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in serous ovarian cancer.
    Martinez VD; Vucic EA; Thu KL; Pikor LA; Hubaux R; Lam WL
    Biomed Res Int; 2014; 2014():159459. PubMed ID: 25114896
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dimer of arfaptin 2 regulates NF-κB signaling by interacting with IKKβ/NEMO and inhibiting IKKβ kinase activity.
    You DJ; Park CR; Furlong M; Koo O; Lee C; Ahn C; Seong JY; Hwang JI
    Cell Signal; 2015 Nov; 27(11):2173-81. PubMed ID: 26296658
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural instability of IκB kinase β promotes autophagic degradation through enhancement of Keap1 binding.
    Kanamoto M; Tsuchiya Y; Nakao Y; Suzuki T; Motohashi H; Yamamoto M; Kamata H
    PLoS One; 2018; 13(11):e0203978. PubMed ID: 30500824
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nuclear IKKbeta is an adaptor protein for IkappaBalpha ubiquitination and degradation in UV-induced NF-kappaB activation.
    Tsuchiya Y; Asano T; Nakayama K; Kato T; Karin M; Kamata H
    Mol Cell; 2010 Aug; 39(4):570-82. PubMed ID: 20797629
    [TBL] [Abstract][Full Text] [Related]  

  • 14. IKKbeta-mediated nuclear factor-kappaB activation attenuates smac mimetic-induced apoptosis in cancer cells.
    Bai L; Chen W; Chen W; Wang X; Tang H; Lin Y
    Mol Cancer Ther; 2009 Jun; 8(6):1636-45. PubMed ID: 19509265
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Diffusion dynamics of the Keap1-Cullin3 interaction in single live cells.
    Baird L; Dinkova-Kostova AT
    Biochem Biophys Res Commun; 2013 Mar; 433(1):58-65. PubMed ID: 23454126
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Disruption of KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex components by multiple genetic mechanisms: Association with poor prognosis in head and neck cancer.
    Martinez VD; Vucic EA; Thu KL; Pikor LA; Lam S; Lam WL
    Head Neck; 2015 May; 37(5):727-34. PubMed ID: 24596130
    [TBL] [Abstract][Full Text] [Related]  

  • 17. IKKalpha and IKKbeta each function to regulate NF-kappaB activation in the TNF-induced/canonical pathway.
    Adli M; Merkhofer E; Cogswell P; Baldwin AS
    PLoS One; 2010 Feb; 5(2):e9428. PubMed ID: 20195534
    [TBL] [Abstract][Full Text] [Related]  

  • 18. EGFR-induced and PKCε monoubiquitylation-dependent NF-κB activation upregulates PKM2 expression and promotes tumorigenesis.
    Yang W; Xia Y; Cao Y; Zheng Y; Bu W; Zhang L; You MJ; Koh MY; Cote G; Aldape K; Li Y; Verma IM; Chiao PJ; Lu Z
    Mol Cell; 2012 Dec; 48(5):771-84. PubMed ID: 23123196
    [TBL] [Abstract][Full Text] [Related]  

  • 19.
    Yang S; Deng Q; Sun L; Zhu Y; Dong K; Wu S; Huang R; Li Y
    Front Cell Infect Microbiol; 2021; 11():641412. PubMed ID: 33816345
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NEMO-binding domains of both IKKalpha and IKKbeta regulate IkappaB kinase complex assembly and classical NF-kappaB activation.
    Solt LA; Madge LA; May MJ
    J Biol Chem; 2009 Oct; 284(40):27596-608. PubMed ID: 19666475
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.