These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

48 related articles for article (PubMed ID: 19819138)

  • 1. Pyrazolo[1,5-a]pyrimidine-based inhibitors of HCV polymerase.
    Popovici-Muller J; Shipps GW; Rosner KE; Deng Y; Wang T; Curran PJ; Brown MA; Siddiqui MA; Cooper AB; Duca J; Cable M; Girijavallabhan V
    Bioorg Med Chem Lett; 2009 Nov; 19(22):6331-6. PubMed ID: 19819138
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Non-nucleoside inhibitors of the HCV polymerase.
    Sarisky RT
    J Antimicrob Chemother; 2004 Jul; 54(1):14-6. PubMed ID: 15190019
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aminothiazole inhibitors of HCV RNA polymerase.
    Shipps GW; Deng Y; Wang T; Popovici-Muller J; Curran PJ; Rosner KE; Cooper AB; Girijavallabhan V; Butkiewicz N; Cable M
    Bioorg Med Chem Lett; 2005 Jan; 15(1):115-9. PubMed ID: 15582422
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and SAR of novel 1,1-dialkyl-2(1H)-naphthalenones as potent HCV polymerase inhibitors.
    Bosse TD; Larson DP; Wagner R; Hutchinson DK; Rockway TW; Kati WM; Liu Y; Masse S; Middleton T; Mo H; Montgomery D; Jiang W; Koev G; Kempf DJ; Molla A
    Bioorg Med Chem Lett; 2008 Jan; 18(2):568-70. PubMed ID: 18068361
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of substituted pyrazolo[1,5-a]quinazolin-5(4H)-one as potent poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors.
    Orvieto F; Branca D; Giomini C; Jones P; Koch U; Ontoria JM; Palumbi MC; Rowley M; Toniatti C; Muraglia E
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4196-200. PubMed ID: 19541484
    [TBL] [Abstract][Full Text] [Related]  

  • 6. New acridone-4-carboxylic acid derivatives as potential inhibitors of hepatitis C virus infection.
    Stankiewicz-Drogon A; Palchykovska LG; Kostina VG; Alexeeva IV; Shved AD; Boguszewska-Chachulska AM
    Bioorg Med Chem; 2008 Oct; 16(19):8846-52. PubMed ID: 18801660
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A homogeneous, solid-phase assay for hepatitis C virus RNA-dependent RNA polymerase.
    Wang YK; Rigat KL; Roberts SB; Gao M
    Anal Biochem; 2006 Dec; 359(1):106-11. PubMed ID: 17054898
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel pyrazolo[3,4-d]pyrimidine-based inhibitors of Staphlococcus aureus DNA polymerase III: design, synthesis, and biological evaluation.
    Ali A; Taylor GE; Ellsworth K; Harris G; Painter R; Silver LL; Young K
    J Med Chem; 2003 May; 46(10):1824-30. PubMed ID: 12723946
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Docking ligands into flexible and solvated macromolecules. 2. Development and application of fitted 1.5 to the virtual screening of potential HCV polymerase inhibitors.
    Corbeil CR; Englebienne P; Yannopoulos CG; Chan L; Das SK; Bilimoria D; L'heureux L; Moitessier N
    J Chem Inf Model; 2008 Apr; 48(4):902-9. PubMed ID: 18341269
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Simple but highly effective three-dimensional chemical-feature-based pharmacophore model for diketo acid derivatives as hepatitis C virus RNA-dependent RNA polymerase inhibitors.
    Di Santo R; Fermeglia M; Ferrone M; Paneni MS; Costi R; Artico M; Roux A; Gabriele M; Tardif KD; Siddiqui A; Pricl S
    J Med Chem; 2005 Oct; 48(20):6304-14. PubMed ID: 16190757
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological characterization of B-ring amino analogues of potent benzothiadiazine hepatitis C virus polymerase inhibitors.
    Randolph JT; Flentge CA; Huang PP; Hutchinson DK; Klein LL; Lim HB; Mondal R; Reisch T; Montgomery DA; Jiang WW; Masse SV; Hernandez LE; Henry RF; Liu Y; Koev G; Kati WM; Stewart KD; Beno DW; Molla A; Kempf DJ
    J Med Chem; 2009 May; 52(10):3174-83. PubMed ID: 19402666
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Recent advances in the analysis of HCV NS5B RNA-dependent RNA polymerase.
    Lesburg CA; Radfar R; Weber PC
    Curr Opin Investig Drugs; 2000 Nov; 1(3):289-96. PubMed ID: 11249710
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of novel HCV RNA-dependent RNA polymerase inhibitors using pharmacophore-guided virtual screening.
    Kim J; Kim KS; Kim DE; Chong Y
    Chem Biol Drug Des; 2008 Dec; 72(6):585-91. PubMed ID: 19090925
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human immunodeficiency virus-reverse transcriptase inhibition and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of fullerene derivatives.
    Mashino T; Shimotohno K; Ikegami N; Nishikawa D; Okuda K; Takahashi K; Nakamura S; Mochizuki M
    Bioorg Med Chem Lett; 2005 Feb; 15(4):1107-9. PubMed ID: 15686922
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibitors of hepatitis C virus polymerase: synthesis and biological characterization of unsymmetrical dialkyl-hydroxynaphthalenoyl-benzothiadiazines.
    Wagner R; Larson DP; Beno DW; Bosse TD; Darbyshire JF; Gao Y; Gates BD; He W; Henry RF; Hernandez LE; Hutchinson DK; Jiang WW; Kati WM; Klein LL; Koev G; Kohlbrenner W; Krueger AC; Liu J; Liu Y; Long MA; Maring CJ; Masse SV; Middleton T; Montgomery DA; Pratt JK; Stuart P; Molla A; Kempf DJ
    J Med Chem; 2009 Mar; 52(6):1659-69. PubMed ID: 19226162
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification and characterization of mutations conferring resistance to an HCV RNA-dependent RNA polymerase inhibitor in vitro.
    Lu L; Dekhtyar T; Masse S; Pithawalla R; Krishnan P; He W; Ng T; Koev G; Stewart K; Larson D; Bosse T; Wagner R; Pilot-Matias T; Mo H; Molla A
    Antiviral Res; 2007 Oct; 76(1):93-7. PubMed ID: 17561278
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hit to lead optimization of pyrazolo[1,5-a]pyrimidines as B-Raf kinase inhibitors.
    Gopalsamy A; Ciszewski G; Shi M; Berger D; Hu Y; Lee F; Feldberg L; Frommer E; Kim S; Collins K; Wojciechowicz D; Mallon R
    Bioorg Med Chem Lett; 2009 Dec; 19(24):6890-2. PubMed ID: 19884006
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of 1'-C-cyano pyrimidine nucleosides and characterization as HCV polymerase inhibitors.
    Kirschberg TA; Mish M; Squires NH; Zonte S; Aktoudianakis E; Metobo S; Butler T; Ju X; Cho A; Ray AS; Kim CU
    Nucleosides Nucleotides Nucleic Acids; 2015; 34(11):763-85. PubMed ID: 26398773
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A study of the allosteric inhibition of HCV RNA-dependent RNA polymerase and implementing virtual screening for the selection of promising dual-site inhibitors with low resistance potential.
    Ismail NSM; Elzahabi HSA; Sabry P; Baselious FN; AbdelMalak AS; Hanna F
    J Recept Signal Transduct Res; 2017 Aug; 37(4):341-354. PubMed ID: 27829320
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Non-nucleoside analogue polymerase inhibitors in development.
    Pockros PJ
    Clin Liver Dis; 2013 Feb; 17(1):123-8. PubMed ID: 23177288
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 3.