BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 19819766)

  • 1. Identification and measurement of isoaspartic acid formation in the complementarity determining region of a fully human monoclonal antibody.
    Dick LW; Qiu D; Cheng KC
    J Chromatogr B Analyt Technol Biomed Life Sci; 2009 Nov; 877(30):3841-9. PubMed ID: 19819766
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Isomerization in the CDR2 of a monoclonal antibody: Binding analysis and factors that influence the isomerization rate.
    Dick LW; Qiu D; Wong RB; Cheng KC
    Biotechnol Bioeng; 2010 Feb; 105(3):515-23. PubMed ID: 19806678
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of the isomerization products of aspartate residues at two different sites in a monoclonal antibody.
    Sreedhara A; Cordoba A; Zhu Q; Kwong J; Liu J
    Pharm Res; 2012 Jan; 29(1):187-97. PubMed ID: 21809161
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-Function Assessment and High-Throughput Quantification of Site-Specific Aspartate Isomerization in Monoclonal Antibody Using a Novel Analytical Tool Kit.
    Zhou K; Cao X; Bautista J; Chen Z; Hershey N; Ludwig R; Tao L; Zeng M; Das TK
    J Pharm Sci; 2020 Jan; 109(1):422-428. PubMed ID: 31469998
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ion-pair reversed-phase high performance liquid chromatography method for the quantification of isoaspartic acid in a monoclonal antibody.
    Kern W; Mende R; Denefeld B; Sackewitz M; Chelius D
    J Chromatogr B Analyt Technol Biomed Life Sci; 2014 Apr; 955-956():26-33. PubMed ID: 24631807
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Aspartate isomerization in the complementarity-determining regions of two closely related monoclonal antibodies.
    Wakankar AA; Borchardt RT; Eigenbrot C; Shia S; Wang YJ; Shire SJ; Liu JL
    Biochemistry; 2007 Feb; 46(6):1534-44. PubMed ID: 17279618
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Separation and characterization of an IgG2 antibody containing a cyclic imide in CDR1 of light chain by hydrophobic interaction chromatography and mass spectrometry.
    Valliere-Douglass J; Jones L; Shpektor D; Kodama P; Wallace A; Balland A; Bailey R; Zhang Y
    Anal Chem; 2008 May; 80(9):3168-74. PubMed ID: 18355059
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification and characterization of monoclonal antibody fragments cleaved at the complementarity determining region using orthogonal analytical methods.
    Li W; Yang B; Zhou D; Xu J; Li W; Suen WC
    J Chromatogr B Analyt Technol Biomed Life Sci; 2017 Mar; 1048():121-129. PubMed ID: 28242491
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Unequivocal Identification of Aspartic Acid and
    Hui JO; Flick T; Loo JA; Campuzano IDG
    J Am Soc Mass Spectrom; 2021 Aug; 32(8):1901-1909. PubMed ID: 33390012
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Qualification of a Quantitative Method for Monitoring Aspartate Isomerization of a Monoclonal Antibody by Focused Peptide Mapping.
    Cao M; Mo WD; Shannon A; Wei Z; Washabaugh M; Cash P
    PDA J Pharm Sci Technol; 2016 11/12; 70(6):490-507. PubMed ID: 27091886
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Probing deamidation in therapeutic immunoglobulin gamma (IgG1) by 'bottom-up' mass spectrometry with electron transfer dissociation.
    Mukherjee R; Adhikary L; Khedkar A; Iyer H
    Rapid Commun Mass Spectrom; 2010 Apr; 24(7):879-84. PubMed ID: 20196189
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Isomerization of an aspartic acid residue in the complementarity-determining regions of a recombinant antibody to human IgE: identification and effect on binding affinity.
    Cacia J; Keck R; Presta LG; Frenz J
    Biochemistry; 1996 Feb; 35(6):1897-903. PubMed ID: 8639672
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of a high-affinity human antibody with a disulfide bridge in the third complementarity-determining region of the heavy chain.
    Almagro JC; Raghunathan G; Beil E; Janecki DJ; Chen Q; Dinh T; LaCombe A; Connor J; Ware M; Kim PH; Swanson RV; Fransson J
    J Mol Recognit; 2012 Mar; 25(3):125-35. PubMed ID: 22407976
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of Asp isomerization in proteins by ¹⁸O labeling and tandem mass spectrometry.
    Zhang J; Katta V
    Methods Mol Biol; 2012; 899():365-77. PubMed ID: 22735965
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of isomerization and racemization of aspartate in the Asp-Asp motifs of a therapeutic protein.
    Zhang J; Yip H; Katta V
    Anal Biochem; 2011 Mar; 410(2):234-43. PubMed ID: 21130067
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of deamidation and isomerization sites on pharmaceutical recombinant antibody using H(2)(18)O.
    Terashima I; Koga A; Nagai H
    Anal Biochem; 2007 Sep; 368(1):49-60. PubMed ID: 17617368
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HIC resolution of an IgG1 with an oxidized Trp in a complementarity determining region.
    Boyd D; Kaschak T; Yan B
    J Chromatogr B Analyt Technol Biomed Life Sci; 2011 Apr; 879(13-14):955-60. PubMed ID: 21440514
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Isomerization and Oxidation in the Complementarity-Determining Regions of a Monoclonal Antibody: A Study of the Modification-Structure-Function Correlations by Hydrogen-Deuterium Exchange Mass Spectrometry.
    Yan Y; Wei H; Fu Y; Jusuf S; Zeng M; Ludwig R; Krystek SR; Chen G; Tao L; Das TK
    Anal Chem; 2016 Feb; 88(4):2041-50. PubMed ID: 26824491
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody.
    Vlasak J; Bussat MC; Wang S; Wagner-Rousset E; Schaefer M; Klinguer-Hamour C; Kirchmeier M; Corvaïa N; Ionescu R; Beck A
    Anal Biochem; 2009 Sep; 392(2):145-54. PubMed ID: 19497295
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 18O labeling method for identification and quantification of succinimide in proteins.
    Xiao G; Bondarenko PV; Jacob J; Chu GC; Chelius D
    Anal Chem; 2007 Apr; 79(7):2714-21. PubMed ID: 17313184
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.