These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 19821461)

  • 1. Synthesis of a resorcylic acid lactone (RAL) library using fluorous-mixture synthesis and profile of its selectivity against a panel of kinases.
    Jogireddy R; Dakas PY; Valot G; Barluenga S; Winssinger N
    Chemistry; 2009 Nov; 15(43):11498-506. PubMed ID: 19821461
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Isosteric replacement of the Z-enone with haloethyl ketone and E-enone in a resorcylic acid lactone series and biological evaluation.
    Napolitano C; Natoni A; Santocanale C; Evensen L; Lorens JB; Murphy PV
    Bioorg Med Chem Lett; 2011 Feb; 21(4):1167-70. PubMed ID: 21273066
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular editing of kinase-targeting resorcylic acid lactones (RAL): Fluoroenone RAL.
    Jogireddy R; Barluenga S; Winssinger N
    ChemMedChem; 2010 May; 5(5):670-3. PubMed ID: 20209566
    [No Abstract]   [Full Text] [Related]  

  • 4. Diversity-oriented synthesis of pochonins and biological evaluation against a panel of kinases.
    Moulin E; Barluenga S; Totzke F; Winssinger N
    Chemistry; 2006 Nov; 12(34):8819-34. PubMed ID: 16953513
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeted covalent inactivation of protein kinases by resorcylic acid lactone polyketides.
    Schirmer A; Kennedy J; Murli S; Reid R; Santi DV
    Proc Natl Acad Sci U S A; 2006 Mar; 103(11):4234-9. PubMed ID: 16537514
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An efficient synthesis of an exo-enone analogue of LL-Z1640-2 and evaluation of its protein kinase inhibitory activities.
    Wang SQ; Goh SS; Chai CLL; Chen A
    Org Biomol Chem; 2016 Jan; 14(2):639-645. PubMed ID: 26541872
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Conformational analyses and MO studies of f152A1 and its analogues as potent protein kinase inhibitors.
    Ikemori-Kawada M; Kawai T; Goto M; Wang YJ; Kawakami Y
    J Chem Inf Model; 2009 Dec; 49(12):2650-9. PubMed ID: 19995092
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rational design of resorcylic acid lactone analogues as covalent MNK1/2 kinase inhibitors by tuning the reactivity of an enamide Michael acceptor.
    Xu J; Chen A; Joy J; Xavier VJ; Ong EH; Hill J; Chai CL
    ChemMedChem; 2013 Sep; 8(9):1483-94. PubMed ID: 23929665
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cis-enone resorcylic acid lactones (RALs) as irreversible protein kinase inhibitors.
    Wei L; Wu J; Li G; Shi N
    Curr Pharm Des; 2012; 18(9):1186-98. PubMed ID: 22316158
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular modeling and crystal structure of ERK2-hypothemycin complexes.
    Rastelli G; Rosenfeld R; Reid R; Santi DV
    J Struct Biol; 2008 Oct; 164(1):18-23. PubMed ID: 18571434
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological testing of purine derivatives as potential ATP-competitive kinase inhibitors.
    Laufer SA; Domeyer DM; Scior TR; Albrecht W; Hauser DR
    J Med Chem; 2005 Feb; 48(3):710-22. PubMed ID: 15689155
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rapid assembly of resorcylic acid lactone frameworks through sequential palladium-catalyzed coupling reactions.
    Fuse S; Sugiyama S; Takahashi T
    Chem Asian J; 2010 Dec; 5(12):2459-62. PubMed ID: 20872399
    [No Abstract]   [Full Text] [Related]  

  • 13. Docking simulation study and kinase selectivity of f152A1 and its analogs.
    Ikemori-Kawada M; Inoue A; Goto M; Wang YJ; Kawakami Y
    J Chem Inf Model; 2012 Aug; 52(8):2059-68. PubMed ID: 22830536
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-activity relationships and enzyme inhibition of pantothenamide-type pantothenate kinase inhibitors.
    Virga KG; Zhang YM; Leonardi R; Ivey RA; Hevener K; Park HW; Jackowski S; Rock CO; Lee RE
    Bioorg Med Chem; 2006 Feb; 14(4):1007-20. PubMed ID: 16213731
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Progress in the design of selective ATP-competitive kinase inhibitors].
    Deng XQ; Xiang ML; Jia R; Yang SY
    Yao Xue Xue Bao; 2007 Dec; 42(12):1232-6. PubMed ID: 18338633
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors.
    Woods KW; Fischer JP; Claiborne A; Li T; Thomas SA; Zhu GD; Diebold RB; Liu X; Shi Y; Klinghofer V; Han EK; Guan R; Magnone SR; Johnson EF; Bouska JJ; Olson AM; de Jong R; Oltersdorf T; Luo Y; Rosenberg SH; Giranda VL; Li Q
    Bioorg Med Chem; 2006 Oct; 14(20):6832-46. PubMed ID: 16843670
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Divergent syntheses of resorcylic acid lactones: L-783277, LL-Z1640-2, and hypothemycin.
    Dakas PY; Jogireddy R; Valot G; Barluenga S; Winssinger N
    Chemistry; 2009 Nov; 15(43):11490-7. PubMed ID: 19821460
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gini coefficient: a new way to express selectivity of kinase inhibitors against a family of kinases.
    Graczyk PP
    J Med Chem; 2007 Nov; 50(23):5773-9. PubMed ID: 17948979
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Selectivity of kinase inhibitor fragments.
    Bamborough P; Brown MJ; Christopher JA; Chung CW; Mellor GW
    J Med Chem; 2011 Jul; 54(14):5131-43. PubMed ID: 21699136
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design and effective synthesis of novel templates, 3,7-diphenyl-4-amino-thieno and furo-[3,2-c]pyridines as protein kinase inhibitors and in vitro evaluation targeting angiogenetic kinases.
    Miyazaki Y; Nakano M; Sato H; Truesdale AT; Stuart JD; Nartey EN; Hightower KE; Kane-Carson L
    Bioorg Med Chem Lett; 2007 Jan; 17(1):250-4. PubMed ID: 17027260
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.