BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

305 related articles for article (PubMed ID: 19822523)

  • 1. p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity.
    Wendt MK; Smith JA; Schiemann WP
    J Biol Chem; 2009 Dec; 284(49):34145-56. PubMed ID: 19822523
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-beta signaling and metastasis.
    Wendt MK; Schiemann WP
    Breast Cancer Res; 2009; 11(5):R68. PubMed ID: 19740433
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lysyl oxidase contributes to mechanotransduction-mediated regulation of transforming growth factor-β signaling in breast cancer cells.
    Taylor MA; Amin JD; Kirschmann DA; Schiemann WP
    Neoplasia; 2011 May; 13(5):406-18. PubMed ID: 21532881
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Src phosphorylates Tyr284 in TGF-beta type II receptor and regulates TGF-beta stimulation of p38 MAPK during breast cancer cell proliferation and invasion.
    Galliher AJ; Schiemann WP
    Cancer Res; 2007 Apr; 67(8):3752-8. PubMed ID: 17440088
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PGE2 receptor EP2 mediates the antagonistic effect of COX-2 on TGF-beta signaling during mammary tumorigenesis.
    Tian M; Schiemann WP
    FASEB J; 2010 Apr; 24(4):1105-16. PubMed ID: 19897661
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Grb2 binding to Tyr284 in TbetaR-II is essential for mammary tumor growth and metastasis stimulated by TGF-beta.
    Galliher-Beckley AJ; Schiemann WP
    Carcinogenesis; 2008 Feb; 29(2):244-51. PubMed ID: 18174260
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cox-2 inactivates Smad signaling and enhances EMT stimulated by TGF-beta through a PGE2-dependent mechanisms.
    Neil JR; Johnson KM; Nemenoff RA; Schiemann WP
    Carcinogenesis; 2008 Nov; 29(11):2227-35. PubMed ID: 18725385
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Beta3 integrin and Src facilitate transforming growth factor-beta mediated induction of epithelial-mesenchymal transition in mammary epithelial cells.
    Galliher AJ; Schiemann WP
    Breast Cancer Res; 2006; 8(4):R42. PubMed ID: 16859511
    [TBL] [Abstract][Full Text] [Related]  

  • 9. p130Cas induces bone invasion by oral squamous cell carcinoma by regulating tumor epithelial-mesenchymal transition and cell proliferation.
    Yaginuma T; Gao J; Nagata K; Muroya R; Fei H; Nagano H; Chishaki S; Matsubara T; Kokabu S; Matsuo K; Kiyoshima T; Yoshioka I; Jimi E
    Carcinogenesis; 2020 Aug; 41(8):1038-1048. PubMed ID: 31996896
    [TBL] [Abstract][Full Text] [Related]  

  • 10. X-linked inhibitor of apoptosis protein and its E3 ligase activity promote transforming growth factor-{beta}-mediated nuclear factor-{kappa}B activation during breast cancer progression.
    Neil JR; Tian M; Schiemann WP
    J Biol Chem; 2009 Aug; 284(32):21209-17. PubMed ID: 19531477
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis.
    Petersen M; Pardali E; van der Horst G; Cheung H; van den Hoogen C; van der Pluijm G; Ten Dijke P
    Oncogene; 2010 Mar; 29(9):1351-61. PubMed ID: 20010874
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The integrin-coupled signaling adaptor p130Cas suppresses Smad3 function in transforming growth factor-beta signaling.
    Kim W; Seok Kang Y; Soo Kim J; Shin NY; Hanks SK; Song WK
    Mol Biol Cell; 2008 May; 19(5):2135-46. PubMed ID: 18321991
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutant p53 disrupts role of ShcA protein in balancing Smad protein-dependent and -independent signaling activity of transforming growth factor-β (TGF-β).
    Lin S; Yu L; Yang J; Liu Z; Karia B; Bishop AJR; Jackson J; Lozano G; Copland JA; Mu X; Sun B; Sun LZ
    J Biol Chem; 2011 Dec; 286(51):44023-44034. PubMed ID: 22039050
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Smad2 and Smad3 phosphorylated at both linker and COOH-terminal regions transmit malignant TGF-beta signal in later stages of human colorectal cancer.
    Matsuzaki K; Kitano C; Murata M; Sekimoto G; Yoshida K; Uemura Y; Seki T; Taketani S; Fujisawa J; Okazaki K
    Cancer Res; 2009 Jul; 69(13):5321-30. PubMed ID: 19531654
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibitory effect of a TGFbeta receptor type-I inhibitor, Ki26894, on invasiveness of scirrhous gastric cancer cells.
    Shinto O; Yashiro M; Kawajiri H; Shimizu K; Shimizu T; Miwa A; Hirakawa K
    Br J Cancer; 2010 Mar; 102(5):844-51. PubMed ID: 20145621
    [TBL] [Abstract][Full Text] [Related]  

  • 16. OSR1 phosphorylates the Smad2/3 linker region and induces TGF-β1 autocrine to promote EMT and metastasis in breast cancer.
    Li Y; Li L; Qin J; Wu J; Dai X; Xu J
    Oncogene; 2021 Jan; 40(1):68-84. PubMed ID: 33051597
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: the role of Smad3.
    Yang F; Chung AC; Huang XR; Lan HY
    Hypertension; 2009 Oct; 54(4):877-84. PubMed ID: 19667256
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p130Cas controls the susceptibility of cancer cells to TGF-β-induced growth inhibition.
    Kang YS; Jeong DE; Lee EK; Song WK; Kim W
    Biochem Biophys Res Commun; 2013 Aug; 438(1):116-21. PubMed ID: 23872147
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling.
    Brown KA; Pietenpol JA; Moses HL
    J Cell Biochem; 2007 May; 101(1):9-33. PubMed ID: 17340614
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β.
    Parvani JG; Galliher-Beckley AJ; Schiemann BJ; Schiemann WP
    Mol Biol Cell; 2013 Nov; 24(21):3449-59. PubMed ID: 24006485
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.