These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 19823097)

  • 1. Preclinical studies of apogossypolone, a novel pan inhibitor of bcl-2 and mcl-1, synergistically potentiates cytotoxic effect of gemcitabine in pancreatic cancer cells.
    Banerjee S; Choi M; Aboukameel A; Wang Z; Mohammad M; Chen J; Yang D; Sarkar FH; Mohammad RM
    Pancreas; 2010 Apr; 39(3):323-31. PubMed ID: 19823097
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Preclinical studies of Apogossypolone: a new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in Follicular Small Cleaved Cell Lymphoma model.
    Arnold AA; Aboukameel A; Chen J; Yang D; Wang S; Al-Katib A; Mohammad RM
    Mol Cancer; 2008 Feb; 7():20. PubMed ID: 18275607
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo.
    Sun Y; Wu J; Aboukameel A; Banerjee S; Arnold AA; Chen J; Nikolovska-Coleska Z; Lin Y; Ling X; Yang D; Wang S; Al-Katib A; Mohammad RM
    Cancer Biol Ther; 2008 Sep; 7(9):1418-26. PubMed ID: 18769131
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synergistic antitumoral activity and induction of apoptosis by novel pan Bcl-2 proteins inhibitor apogossypolone with adriamycin in human hepatocellular carcinoma.
    Mi JX; Wang GF; Wang HB; Sun XQ; Ni XY; Zhang XW; Tang JM; Yang DJ
    Acta Pharmacol Sin; 2008 Dec; 29(12):1467-77. PubMed ID: 19026166
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Apogossypolone induces autophagy and apoptosis in breast cancer MCF-7 cells in vitro and in vivo.
    Niu X; Li S; Wei F; Huang J; Wu G; Xu L; Xu D; Wang S
    Breast Cancer; 2014 Mar; 21(2):223-30. PubMed ID: 22711315
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ApoG2 inhibits antiapoptotic Bcl-2 family proteins and induces mitochondria-dependent apoptosis in human lymphoma U937 cells.
    Sun J; Li ZM; Hu ZY; Lin XB; Zhou NN; Xian LJ; Yang DJ; Jiang WQ
    Anticancer Drugs; 2008 Nov; 19(10):967-74. PubMed ID: 18827561
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ApoG2 inhibits the antiapoptotic protein, Mcl‑1, and induces mitochondria‑dependent apoptosis in human colorectal cancer cells.
    Li T; Yuan G; Zhang L; Ye L; Li S; Fan Y; Sun J
    Mol Med Rep; 2015 Nov; 12(5):6976-84. PubMed ID: 26352605
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Apogossypolone, a small-molecule inhibitor of Bcl-2, induces radiosensitization of nasopharyngeal carcinoma cells by stimulating autophagy.
    He JH; Liao XL; Wang W; Li DD; Chen WD; Deng R; Yang D; Han ZP; Jiang JW; Zhu XF
    Int J Oncol; 2014 Sep; 45(3):1099-108. PubMed ID: 24919770
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ApoG2 as the most potent gossypol derivatives inhibits cell growth and induces apoptosis on gastric cancer cells.
    Xin J; Zhan YH; Xia LM; Zhu HW; Nie YZ; Liang JM; Tian J
    Biomed Pharmacother; 2013 Feb; 67(1):88-95. PubMed ID: 23201009
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combination therapy with gossypol reveals synergism against gemcitabine resistance in cancer cells with high BCL-2 expression.
    Wong FY; Liem N; Xie C; Yan FL; Wong WC; Wang L; Yong WP
    PLoS One; 2012; 7(12):e50786. PubMed ID: 23226540
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of Mcl-1 with the pan-Bcl-2 family inhibitor (-)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia.
    Pan R; Ruvolo VR; Wei J; Konopleva M; Reed JC; Pellecchia M; Andreeff M; Ruvolo PP
    Blood; 2015 Jul; 126(3):363-72. PubMed ID: 26045609
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ApoG2, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces apoptosis and suppresses tumor growth in nasopharyngeal carcinoma xenografts.
    Hu ZY; Zhu XF; Zhong ZD; Sun J; Wang J; Yang D; Zeng YX
    Int J Cancer; 2008 Nov; 123(10):2418-29. PubMed ID: 18712728
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CDK inhibitors upregulate BH3-only proteins to sensitize human myeloma cells to BH3 mimetic therapies.
    Chen S; Dai Y; Pei XY; Myers J; Wang L; Kramer LB; Garnett M; Schwartz DM; Su F; Simmons GL; Richey JD; Larsen DG; Dent P; Orlowski RZ; Grant S
    Cancer Res; 2012 Aug; 72(16):4225-37. PubMed ID: 22693249
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synergistic antitumor activity of gemcitabine and ABT-737 in vitro and in vivo through disrupting the interaction of USP9X and Mcl-1.
    Zhang C; Cai TY; Zhu H; Yang LQ; Jiang H; Dong XW; Hu YZ; Lin NM; He QJ; Yang B
    Mol Cancer Ther; 2011 Jul; 10(7):1264-75. PubMed ID: 21566062
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Resistance of pancreatic cancer to gemcitabine treatment is dependent on mitochondria-mediated apoptosis.
    Schniewind B; Christgen M; Kurdow R; Haye S; Kremer B; Kalthoff H; Ungefroren H
    Int J Cancer; 2004 Mar; 109(2):182-8. PubMed ID: 14750167
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chemoresistance is associated with increased cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (-)-Gossypol (AT-101).
    Mani J; Vallo S; Rakel S; Antonietti P; Gessler F; Blaheta R; Bartsch G; Michaelis M; Cinatl J; Haferkamp A; Kögel D
    BMC Cancer; 2015 Apr; 15():224. PubMed ID: 25885284
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proapoptotic and antiapoptotic proteins of the Bcl-2 family regulate sensitivity of pancreatic cancer cells toward gemcitabine and T-cell-mediated cytotoxicity.
    Bauer C; Hees C; Sterzik A; Bauernfeind F; Mak'Anyengo R; Duewell P; Lehr HA; Noessner E; Wank R; Trauzold A; Endres S; Dauer M; Schnurr M
    J Immunother; 2015 Apr; 38(3):116-26. PubMed ID: 25751501
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Acquired resistance of pancreatic cancer cells towards 5-Fluorouracil and gemcitabine is associated with altered expression of apoptosis-regulating genes.
    Shi X; Liu S; Kleeff J; Friess H; Büchler MW
    Oncology; 2002; 62(4):354-62. PubMed ID: 12138244
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2.
    Yue W; Zheng X; Lin Y; Yang CS; Xu Q; Carpizo D; Huang H; DiPaola RS; Tan XL
    Oncotarget; 2015 Aug; 6(25):21208-24. PubMed ID: 26056043
    [TBL] [Abstract][Full Text] [Related]  

  • 20. BH3 Mimetic ABT-199 Enhances the Sensitivity of Gemcitabine in Pancreatic Cancer in vitro and in vivo.
    Zhou Y; Liu H; Xue R; Tang W; Zhang S
    Dig Dis Sci; 2018 Dec; 63(12):3367-3375. PubMed ID: 30155839
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.