220 related articles for article (PubMed ID: 19823097)
1. Preclinical studies of apogossypolone, a novel pan inhibitor of bcl-2 and mcl-1, synergistically potentiates cytotoxic effect of gemcitabine in pancreatic cancer cells.
Banerjee S; Choi M; Aboukameel A; Wang Z; Mohammad M; Chen J; Yang D; Sarkar FH; Mohammad RM
Pancreas; 2010 Apr; 39(3):323-31. PubMed ID: 19823097
[TBL] [Abstract][Full Text] [Related]
2. Preclinical studies of Apogossypolone: a new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in Follicular Small Cleaved Cell Lymphoma model.
Arnold AA; Aboukameel A; Chen J; Yang D; Wang S; Al-Katib A; Mohammad RM
Mol Cancer; 2008 Feb; 7():20. PubMed ID: 18275607
[TBL] [Abstract][Full Text] [Related]
3. Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo.
Sun Y; Wu J; Aboukameel A; Banerjee S; Arnold AA; Chen J; Nikolovska-Coleska Z; Lin Y; Ling X; Yang D; Wang S; Al-Katib A; Mohammad RM
Cancer Biol Ther; 2008 Sep; 7(9):1418-26. PubMed ID: 18769131
[TBL] [Abstract][Full Text] [Related]
4. Synergistic antitumoral activity and induction of apoptosis by novel pan Bcl-2 proteins inhibitor apogossypolone with adriamycin in human hepatocellular carcinoma.
Mi JX; Wang GF; Wang HB; Sun XQ; Ni XY; Zhang XW; Tang JM; Yang DJ
Acta Pharmacol Sin; 2008 Dec; 29(12):1467-77. PubMed ID: 19026166
[TBL] [Abstract][Full Text] [Related]
5. Apogossypolone induces autophagy and apoptosis in breast cancer MCF-7 cells in vitro and in vivo.
Niu X; Li S; Wei F; Huang J; Wu G; Xu L; Xu D; Wang S
Breast Cancer; 2014 Mar; 21(2):223-30. PubMed ID: 22711315
[TBL] [Abstract][Full Text] [Related]
6. ApoG2 inhibits antiapoptotic Bcl-2 family proteins and induces mitochondria-dependent apoptosis in human lymphoma U937 cells.
Sun J; Li ZM; Hu ZY; Lin XB; Zhou NN; Xian LJ; Yang DJ; Jiang WQ
Anticancer Drugs; 2008 Nov; 19(10):967-74. PubMed ID: 18827561
[TBL] [Abstract][Full Text] [Related]
7. ApoG2 inhibits the antiapoptotic protein, Mcl‑1, and induces mitochondria‑dependent apoptosis in human colorectal cancer cells.
Li T; Yuan G; Zhang L; Ye L; Li S; Fan Y; Sun J
Mol Med Rep; 2015 Nov; 12(5):6976-84. PubMed ID: 26352605
[TBL] [Abstract][Full Text] [Related]
8. Apogossypolone, a small-molecule inhibitor of Bcl-2, induces radiosensitization of nasopharyngeal carcinoma cells by stimulating autophagy.
He JH; Liao XL; Wang W; Li DD; Chen WD; Deng R; Yang D; Han ZP; Jiang JW; Zhu XF
Int J Oncol; 2014 Sep; 45(3):1099-108. PubMed ID: 24919770
[TBL] [Abstract][Full Text] [Related]
9. ApoG2 as the most potent gossypol derivatives inhibits cell growth and induces apoptosis on gastric cancer cells.
Xin J; Zhan YH; Xia LM; Zhu HW; Nie YZ; Liang JM; Tian J
Biomed Pharmacother; 2013 Feb; 67(1):88-95. PubMed ID: 23201009
[TBL] [Abstract][Full Text] [Related]
10. Combination therapy with gossypol reveals synergism against gemcitabine resistance in cancer cells with high BCL-2 expression.
Wong FY; Liem N; Xie C; Yan FL; Wong WC; Wang L; Yong WP
PLoS One; 2012; 7(12):e50786. PubMed ID: 23226540
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of Mcl-1 with the pan-Bcl-2 family inhibitor (-)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia.
Pan R; Ruvolo VR; Wei J; Konopleva M; Reed JC; Pellecchia M; Andreeff M; Ruvolo PP
Blood; 2015 Jul; 126(3):363-72. PubMed ID: 26045609
[TBL] [Abstract][Full Text] [Related]
12. ApoG2, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces apoptosis and suppresses tumor growth in nasopharyngeal carcinoma xenografts.
Hu ZY; Zhu XF; Zhong ZD; Sun J; Wang J; Yang D; Zeng YX
Int J Cancer; 2008 Nov; 123(10):2418-29. PubMed ID: 18712728
[TBL] [Abstract][Full Text] [Related]
13. CDK inhibitors upregulate BH3-only proteins to sensitize human myeloma cells to BH3 mimetic therapies.
Chen S; Dai Y; Pei XY; Myers J; Wang L; Kramer LB; Garnett M; Schwartz DM; Su F; Simmons GL; Richey JD; Larsen DG; Dent P; Orlowski RZ; Grant S
Cancer Res; 2012 Aug; 72(16):4225-37. PubMed ID: 22693249
[TBL] [Abstract][Full Text] [Related]
14. Synergistic antitumor activity of gemcitabine and ABT-737 in vitro and in vivo through disrupting the interaction of USP9X and Mcl-1.
Zhang C; Cai TY; Zhu H; Yang LQ; Jiang H; Dong XW; Hu YZ; Lin NM; He QJ; Yang B
Mol Cancer Ther; 2011 Jul; 10(7):1264-75. PubMed ID: 21566062
[TBL] [Abstract][Full Text] [Related]
15. Resistance of pancreatic cancer to gemcitabine treatment is dependent on mitochondria-mediated apoptosis.
Schniewind B; Christgen M; Kurdow R; Haye S; Kremer B; Kalthoff H; Ungefroren H
Int J Cancer; 2004 Mar; 109(2):182-8. PubMed ID: 14750167
[TBL] [Abstract][Full Text] [Related]
16. Chemoresistance is associated with increased cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (-)-Gossypol (AT-101).
Mani J; Vallo S; Rakel S; Antonietti P; Gessler F; Blaheta R; Bartsch G; Michaelis M; Cinatl J; Haferkamp A; Kögel D
BMC Cancer; 2015 Apr; 15():224. PubMed ID: 25885284
[TBL] [Abstract][Full Text] [Related]
17. Proapoptotic and antiapoptotic proteins of the Bcl-2 family regulate sensitivity of pancreatic cancer cells toward gemcitabine and T-cell-mediated cytotoxicity.
Bauer C; Hees C; Sterzik A; Bauernfeind F; Mak'Anyengo R; Duewell P; Lehr HA; Noessner E; Wank R; Trauzold A; Endres S; Dauer M; Schnurr M
J Immunother; 2015 Apr; 38(3):116-26. PubMed ID: 25751501
[TBL] [Abstract][Full Text] [Related]
18. Acquired resistance of pancreatic cancer cells towards 5-Fluorouracil and gemcitabine is associated with altered expression of apoptosis-regulating genes.
Shi X; Liu S; Kleeff J; Friess H; Büchler MW
Oncology; 2002; 62(4):354-62. PubMed ID: 12138244
[TBL] [Abstract][Full Text] [Related]
19. Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2.
Yue W; Zheng X; Lin Y; Yang CS; Xu Q; Carpizo D; Huang H; DiPaola RS; Tan XL
Oncotarget; 2015 Aug; 6(25):21208-24. PubMed ID: 26056043
[TBL] [Abstract][Full Text] [Related]
20. BH3 Mimetic ABT-199 Enhances the Sensitivity of Gemcitabine in Pancreatic Cancer in vitro and in vivo.
Zhou Y; Liu H; Xue R; Tang W; Zhang S
Dig Dis Sci; 2018 Dec; 63(12):3367-3375. PubMed ID: 30155839
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]