BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

300 related articles for article (PubMed ID: 19825520)

  • 1. Pharmacological inhibitors of the mevalonate pathway activate pro-IL-1 processing and IL-1 release by human monocytes.
    Massonnet B; Normand S; Moschitz R; Delwail A; Favot L; Garcia M; Bourmeyster N; Cuisset L; Grateau G; Morel F; Silvain C; Lecron JC
    Eur Cytokine Netw; 2009 Sep; 20(3):112-20. PubMed ID: 19825520
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Statin synergizes with LPS to induce IL-1beta release by THP-1 cells through activation of caspase-1.
    Kuijk LM; Mandey SH; Schellens I; Waterham HR; Rijkers GT; Coffer PJ; Frenkel J
    Mol Immunol; 2008 Apr; 45(8):2158-65. PubMed ID: 18242710
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Specific increase in caspase-1 activity and secretion of IL-1 family cytokines: a putative link between mevalonate kinase deficiency and inflammation.
    Normand S; Massonnet B; Delwail A; Favot L; Cuisset L; Grateau G; Morel F; Silvain C; Lecron JC
    Eur Cytokine Netw; 2009 Sep; 20(3):101-7. PubMed ID: 19825518
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Statins suppress THP-1 cell migration and secretion of matrix metalloproteinase 9 by inhibiting geranylgeranylation.
    Wong B; Lumma WC; Smith AM; Sisko JT; Wright SD; Cai TQ
    J Leukoc Biol; 2001 Jun; 69(6):959-62. PubMed ID: 11404382
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A role for geranylgeranylation in interleukin-1beta secretion.
    Mandey SH; Kuijk LM; Frenkel J; Waterham HR
    Arthritis Rheum; 2006 Nov; 54(11):3690-5. PubMed ID: 17075828
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Statin-induced proinflammatory response in mitogen-activated peripheral blood mononuclear cells through the activation of caspase-1 and IL-18 secretion in monocytes.
    Coward WR; Marei A; Yang A; Vasa-Nicotera MM; Chow SC
    J Immunol; 2006 May; 176(9):5284-92. PubMed ID: 16621994
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HMG-CoA reductase inhibition induces IL-1beta release through Rac1/PI3K/PKB-dependent caspase-1 activation.
    Kuijk LM; Beekman JM; Koster J; Waterham HR; Frenkel J; Coffer PJ
    Blood; 2008 Nov; 112(9):3563-73. PubMed ID: 18684863
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HMG-CoA reductase inhibitors activate caspase-1 in human monocytes depending on ATP release and P2X7 activation.
    Liao YH; Lin YC; Tsao ST; Lin YC; Yang AJ; Huang CT; Huang KC; Lin WW
    J Leukoc Biol; 2013 Feb; 93(2):289-99. PubMed ID: 23159926
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Leptin enhances the secretion of interleukin (IL)-18, but not IL-1β, from human monocytes via activation of caspase-1.
    Jitprasertwong P; Jaedicke KM; Nile CJ; Preshaw PM; Taylor JJ
    Cytokine; 2014 Feb; 65(2):222-30. PubMed ID: 24275551
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modulation of COX-2 expression by statins in human monocytic cells.
    Habib A; Shamseddeen I; Nasrallah MS; Antoun TA; Nemer G; Bertoglio J; Badreddine R; Badr KF
    FASEB J; 2007 Jun; 21(8):1665-74. PubMed ID: 17317725
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Defect in mevalonate pathway induces pyroptosis in Raw 264.7 murine monocytes.
    Marcuzzi A; Piscianz E; Girardelli M; Crovella S; Pontillo A
    Apoptosis; 2011 Sep; 16(9):882-8. PubMed ID: 21667041
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Decreased C-reactive protein-induced resistin production in human monocytes by simvastatin.
    Hu WL; Qiao SB; Li JJ
    Cytokine; 2007 Dec; 40(3):201-6. PubMed ID: 18023360
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel aspects of mevalonate pathway inhibitors as antitumor agents.
    Thurnher M; Nussbaumer O; Gruenbacher G
    Clin Cancer Res; 2012 Jul; 18(13):3524-31. PubMed ID: 22529099
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased expression of interleukin-1 in coronary artery disease with downregulatory effects of HMG-CoA reductase inhibitors.
    Waehre T; Yndestad A; Smith C; Haug T; Tunheim SH; Gullestad L; Frøland SS; Semb AG; Aukrust P; Damås JK
    Circulation; 2004 Apr; 109(16):1966-72. PubMed ID: 15051633
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Simvastatin inhibits C-reactive protein-induced pro-inflammatory changes in endothelial cells by decreasing mevalonate pathway products.
    Liang YJ; Shyu KG; Wang BW; Lai LP
    Cardiology; 2008; 110(3):182-90. PubMed ID: 18057884
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Simvastatin reduces lipoprotein-associated phospholipase A2 in lipopolysaccharide-stimulated human monocyte-derived macrophages through inhibition of the mevalonate-geranylgeranyl pyrophosphate-RhoA-p38 mitogen-activated protein kinase pathway.
    Song JX; Ren JY; Chen H
    J Cardiovasc Pharmacol; 2011 Feb; 57(2):213-22. PubMed ID: 21052011
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lack of isoprenoid products raises ex vivo interleukin-1beta secretion in hyperimmunoglobulinemia D and periodic fever syndrome.
    Frenkel J; Rijkers GT; Mandey SH; Buurman SW; Houten SM; Wanders RJ; Waterham HR; Kuis W
    Arthritis Rheum; 2002 Oct; 46(10):2794-803. PubMed ID: 12384940
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation.
    Lee MH; Cho YS; Han YM
    Stem Cells; 2007 Jul; 25(7):1654-63. PubMed ID: 17464088
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HMG-CoA reductase inhibitor simvastatin inhibits proinflammatory cytokine production from murine mast cells.
    Kagami S; Kanari H; Suto A; Fujiwara M; Ikeda K; Hirose K; Watanabe N; Iwamoto I; Nakajima H
    Int Arch Allergy Immunol; 2008; 146 Suppl 1():61-6. PubMed ID: 18504409
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Statins enhance toll-like receptor 4-mediated cytokine gene expression in astrocytes: implication of Rho proteins in negative feedback regulation.
    Konat GW; Krasowska-Zoladek A; Kraszpulski M
    J Neurosci Res; 2008 Feb; 86(3):603-9. PubMed ID: 17896797
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.