BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

436 related articles for article (PubMed ID: 19840668)

  • 1. MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition.
    Böttcher E; Freuer C; Steinmetzer T; Klenk HD; Garten W
    Vaccine; 2009 Oct; 27(45):6324-9. PubMed ID: 19840668
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cleavage of influenza virus hemagglutinin by airway proteases TMPRSS2 and HAT differs in subcellular localization and susceptibility to protease inhibitors.
    Böttcher-Friebertshäuser E; Freuer C; Sielaff F; Schmidt S; Eickmann M; Uhlendorff J; Steinmetzer T; Klenk HD; Garten W
    J Virol; 2010 Jun; 84(11):5605-14. PubMed ID: 20237084
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells.
    Bestle D; Limburg H; Kruhl D; Harbig A; Stein DA; Moulton H; Matrosovich M; Abdelwhab EM; Stech J; Böttcher-Friebertshäuser E
    J Virol; 2021 Sep; 95(20):e0090621. PubMed ID: 34319155
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hemagglutinin activating host cell proteases provide promising drug targets for the treatment of influenza A and B virus infections.
    Böttcher-Friebertshäuser E; Lu Y; Meyer D; Sielaff F; Steinmetzer T; Klenk HD; Garten W
    Vaccine; 2012 Dec; 30(51):7374-80. PubMed ID: 23072892
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium.
    Böttcher E; Matrosovich T; Beyerle M; Klenk HD; Garten W; Matrosovich M
    J Virol; 2006 Oct; 80(19):9896-8. PubMed ID: 16973594
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TMPRSS2 Activates Hemagglutinin-Esterase Glycoprotein of Influenza C Virus.
    Sato K; Hayashi H; Shimotai Y; Yamaya M; Hongo S; Kawakami K; Matsuzaki Y; Nishimura H
    J Virol; 2021 Oct; 95(21):e0129621. PubMed ID: 34406864
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TMPRSS2 Is the Major Activating Protease of Influenza A Virus in Primary Human Airway Cells and Influenza B Virus in Human Type II Pneumocytes.
    Limburg H; Harbig A; Bestle D; Stein DA; Moulton HM; Jaeger J; Janga H; Hardes K; Koepke J; Schulte L; Koczulla AR; Schmeck B; Klenk HD; Böttcher-Friebertshäuser E
    J Virol; 2019 Nov; 93(21):. PubMed ID: 31391268
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Endogenous protease-dependent replication of human influenza viruses in two MDCK cell lines.
    Noma K; Kiyotani K; Kouchi H; Fujii Y; Egi Y; Tanaka K; Yoshida T
    Arch Virol; 1998; 143(10):1893-909. PubMed ID: 9856079
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation.
    Meyer D; Sielaff F; Hammami M; Böttcher-Friebertshäuser E; Garten W; Steinmetzer T
    Biochem J; 2013 Jun; 452(2):331-43. PubMed ID: 23527573
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Influenza virus activating host proteases: Identification, localization and inhibitors as potential therapeutics.
    Garten W; Braden C; Arendt A; Peitsch C; Baron J; Lu Y; Pawletko K; Hardes K; Steinmetzer T; Böttcher-Friebertshäuser E
    Eur J Cell Biol; 2015; 94(7-9):375-83. PubMed ID: 26095298
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases.
    Kühn N; Bergmann S; Kösterke N; Lambertz RLO; Keppner A; van den Brand JMA; Pöhlmann S; Weiß S; Hummler E; Hatesuer B; Schughart K
    J Virol; 2016 May; 90(9):4298-4307. PubMed ID: 26889029
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ACE2 acts as a novel regulator of TMPRSS2-catalyzed proteolytic activation of influenza A virus in airway cells.
    Heindl MR; Rupp A-L; Schwerdtner M; Bestle D; Harbig A; De Rocher A; Schmacke LC; Staker B; Steinmetzer T; Stein DA; Moulton HM; Böttcher-Friebertshäuser E
    J Virol; 2024 Apr; 98(4):e0010224. PubMed ID: 38470058
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparative study of influenza virus replication in Vero and MDCK cell lines.
    Youil R; Su Q; Toner TJ; Szymkowiak C; Kwan WS; Rubin B; Petrukhin L; Kiseleva I; Shaw AR; DiStefano D
    J Virol Methods; 2004 Sep; 120(1):23-31. PubMed ID: 15234806
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transcriptome profiling and protease inhibition experiments identify proteases that activate H3N2 influenza A and influenza B viruses in murine airways.
    Harbig A; Mernberger M; Bittel L; Pleschka S; Schughart K; Steinmetzer T; Stiewe T; Nist A; Böttcher-Friebertshäuser E
    J Biol Chem; 2020 Aug; 295(33):11388-11407. PubMed ID: 32303635
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Matriptase, HAT, and TMPRSS2 activate the hemagglutinin of H9N2 influenza A viruses.
    Baron J; Tarnow C; Mayoli-Nüssle D; Schilling E; Meyer D; Hammami M; Schwalm F; Steinmetzer T; Guan Y; Garten W; Klenk HD; Böttcher-Friebertshäuser E
    J Virol; 2013 Feb; 87(3):1811-20. PubMed ID: 23192872
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Suitability of MDCK cells grown in a serum-free medium for influenza virus production.
    Kessler N; Thomas-Roche G; Gérentes L; Aymard M
    Dev Biol Stand; 1999; 98():13-21; discussion 73-4. PubMed ID: 10494956
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SPINT2 inhibits proteases involved in activation of both influenza viruses and metapneumoviruses.
    Straus MR; Kinder JT; Segall M; Dutch RE; Whittaker GR
    Virology; 2020 Apr; 543():43-53. PubMed ID: 32056846
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel type II transmembrane serine proteases, MSPL and TMPRSS13, Proteolytically activate membrane fusion activity of the hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication.
    Okumura Y; Takahashi E; Yano M; Ohuchi M; Daidoji T; Nakaya T; Böttcher E; Garten W; Klenk HD; Kido H
    J Virol; 2010 May; 84(10):5089-96. PubMed ID: 20219906
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cleavage of influenza a virus hemagglutinin in human respiratory epithelium is cell associated and sensitive to exogenous antiproteases.
    Zhirnov OP; Ikizler MR; Wright PF
    J Virol; 2002 Sep; 76(17):8682-9. PubMed ID: 12163588
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A new approach to an influenza live vaccine: modification of the cleavage site of hemagglutinin.
    Stech J; Garn H; Wegmann M; Wagner R; Klenk HD
    Nat Med; 2005 Jun; 11(6):683-9. PubMed ID: 15924146
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.