340 related articles for article (PubMed ID: 19842660)
1. Exploring the importance of piperazine N-atoms for sigma(2) receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28).
Berardi F; Abate C; Ferorelli S; Uricchio V; Colabufo NA; Niso M; Perrone R
J Med Chem; 2009 Dec; 52(23):7817-28. PubMed ID: 19842660
[TBL] [Abstract][Full Text] [Related]
2. 4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activity.
Berardi F; Ferorelli S; Abate C; Colabufo NA; Contino M; Perrone R; Tortorella V
J Med Chem; 2004 Apr; 47(9):2308-17. PubMed ID: 15084129
[TBL] [Abstract][Full Text] [Related]
3. New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives.
Berardi F; Colabufo NA; Giudice G; Perrone R; Tortorella V; Govoni S; Lucchi L
J Med Chem; 1996 Jan; 39(1):176-82. PubMed ID: 8568804
[TBL] [Abstract][Full Text] [Related]
4. Methyl substitution on the piperidine ring of N-[omega-(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma(1) receptor.
Berardi F; Ferorelli S; Abate C; Pedone MP; Colabufo NA; Contino M; Perrone R
J Med Chem; 2005 Dec; 48(26):8237-44. PubMed ID: 16366605
[TBL] [Abstract][Full Text] [Related]
5. Analogues of σ receptor ligand 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with added polar functionality and reduced lipophilicity for potential use as positron emission tomography radiotracers.
Abate C; Niso M; Lacivita E; Mosier PD; Toscano A; Perrone R
J Med Chem; 2011 Feb; 54(4):1022-32. PubMed ID: 21229979
[TBL] [Abstract][Full Text] [Related]
6. Characterization of novel N,N'-disubstituted piperazines as sigma receptor ligands.
Zhang Y; Williams W; Torrence-Campbell C; Bowen WD; Rice KC
J Med Chem; 1998 Dec; 41(25):4950-7. PubMed ID: 9836612
[TBL] [Abstract][Full Text] [Related]
7. 2-Aminopyridine derivatives as potential σ(2) receptor antagonists.
Abate C; Ferorelli S; Niso M; Lovicario C; Infantino V; Convertini P; Perrone R; Berardi F
ChemMedChem; 2012 Oct; 7(10):1847-57. PubMed ID: 22890883
[TBL] [Abstract][Full Text] [Related]
8. Novel derivatives of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with improved fluorescent and σ receptors binding properties.
Abate C; Niso M; Marottoli R; Riganti C; Ghigo D; Ferorelli S; Ossato G; Perrone R; Lacivita E; Lamb DC; Berardi F
J Med Chem; 2014 Apr; 57(8):3314-23. PubMed ID: 24697311
[TBL] [Abstract][Full Text] [Related]
9. 1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Δ(8)-Δ(7) sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity.
Abate C; Niso M; Contino M; Colabufo NA; Ferorelli S; Perrone R; Berardi F
ChemMedChem; 2011 Jan; 6(1):73-80. PubMed ID: 21069657
[TBL] [Abstract][Full Text] [Related]
10. Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
Leopoldo M; Berardi F; Colabufo NA; Contino M; Lacivita E; Niso M; Perrone R; Tortorella V
J Med Chem; 2004 Dec; 47(26):6616-24. PubMed ID: 15588097
[TBL] [Abstract][Full Text] [Related]
11. Effects of linker elongation in a series of N-(2-benzofuranylmethyl)-N'-(methoxyphenylalkyl)piperazine σ₁ receptor ligands.
Moussa IA; Banister SD; Akladios FN; Chua SW; Kassiou M
Bioorg Med Chem Lett; 2011 Oct; 21(19):5707-10. PubMed ID: 21871797
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and structure-activity relationships of 1-aralkyl-4-benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent sigma ligands.
Costantino L; Gandolfi F; Sorbi C; Franchini S; Prezzavento O; Vittorio F; Ronsisvalle G; Leonardi A; Poggesi E; Brasili L
J Med Chem; 2005 Jan; 48(1):266-73. PubMed ID: 15634021
[TBL] [Abstract][Full Text] [Related]
13. Investigation of σ receptors agonist/antagonist activity through N-(6-methoxytetralin-1-yl)- and N-(6-methoxynaphthalen-1-yl)alkyl derivatives of polymethylpiperidines.
Niso M; Abate C; Ferorelli S; Cassano G; Gasparre G; Perrone R; Berardi F
Bioorg Med Chem; 2013 Apr; 21(7):1865-9. PubMed ID: 23415062
[TBL] [Abstract][Full Text] [Related]
14. Structure-activity comparison of YZ-069, a novel sigma ligand, and four analogs in receptor binding and behavioral studies.
Matsumoto RR; Potelleret FH; Mack A; Pouw B; Zhang Y; Bowen WD
Pharmacol Biochem Behav; 2004 Apr; 77(4):775-81. PubMed ID: 15099923
[TBL] [Abstract][Full Text] [Related]
15. Interaction of the sigma(2) receptor ligand PB28 with the human nucleosome: computational and experimental probes of interaction with the H2A/H2B dimer.
Abate C; Elenewski J; Niso M; Berardi F; Colabufo NA; Azzariti A; Perrone R; Glennon RA
ChemMedChem; 2010 Feb; 5(2):268-73. PubMed ID: 20077462
[TBL] [Abstract][Full Text] [Related]
16. N-[omega-(Tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine are highly potent and selective sigma1 or sigma2 ligands.
Berardi F; Santoro S; Perrone R; Tortorella V; Govoni S; Lucchi L
J Med Chem; 1998 Oct; 41(21):3940-7. PubMed ID: 9767631
[TBL] [Abstract][Full Text] [Related]
17. Fluorescent derivatives of σ receptor ligand 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) as a tool for uptake and cellular localization studies in pancreatic tumor cells.
Abate C; Hornick JR; Spitzer D; Hawkins WG; Niso M; Perrone R; Berardi F
J Med Chem; 2011 Aug; 54(16):5858-67. PubMed ID: 21744858
[TBL] [Abstract][Full Text] [Related]
18. Novel potent sigma 1 ligands: N-[omega-(tetralin-1-yl)alkyl]piperidine derivatives.
Berardi F; Giudice G; Perrone R; Tortorella V; Govoni S; Lucchi L
J Med Chem; 1996 Oct; 39(21):4255-60. PubMed ID: 8863803
[TBL] [Abstract][Full Text] [Related]
19. Relationships between the structure of 6-allyl-6,8-diazabicyclo[3.2.2]nonane derivatives and their sigma receptor affinity and cytotoxic activity.
Holl R; Schepmann D; Grünert R; Bednarski PJ; Wünsch B
Bioorg Med Chem; 2009 Jan; 17(2):777-93. PubMed ID: 19081725
[TBL] [Abstract][Full Text] [Related]
20. Arylamides hybrids of two high-affinity σ2 receptor ligands as tools for the development of PET radiotracers.
Abate C; Ferorelli S; Contino M; Marottoli R; Colabufo NA; Perrone R; Berardi F
Eur J Med Chem; 2011 Sep; 46(9):4733-41. PubMed ID: 21684636
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
