BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

530 related articles for article (PubMed ID: 19843849)

  • 1. Oncogenic KRAS and BRAF differentially regulate hypoxia-inducible factor-1alpha and -2alpha in colon cancer.
    Kikuchi H; Pino MS; Zeng M; Shirasawa S; Chung DC
    Cancer Res; 2009 Nov; 69(21):8499-506. PubMed ID: 19843849
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Oncogenic KRAS modulates mitochondrial metabolism in human colon cancer cells by inducing HIF-1α and HIF-2α target genes.
    Chun SY; Johnson C; Washburn JG; Cruz-Correa MR; Dang DT; Dang LH
    Mol Cancer; 2010 Nov; 9():293. PubMed ID: 21073737
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C; Moore JW; Robertson N; Harris AL
    Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mild chronic hypoxia-induced HIF-2α interacts with c-MYC through competition with HIF-1α to induce hepatocellular carcinoma cell proliferation.
    Mu H; Yu G; Li H; Wang M; Cui Y; Zhang T; Song T; Liu C
    Cell Oncol (Dordr); 2021 Oct; 44(5):1151-1166. PubMed ID: 34339013
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increased activation of the hypoxia-inducible factor pathway in varicose veins.
    Lim CS; Kiriakidis S; Paleolog EM; Davies AH
    J Vasc Surg; 2012 May; 55(5):1427-39. PubMed ID: 22277691
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutant V600E BRAF increases hypoxia inducible factor-1alpha expression in melanoma.
    Kumar SM; Yu H; Edwards R; Chen L; Kazianis S; Brafford P; Acs G; Herlyn M; Xu X
    Cancer Res; 2007 Apr; 67(7):3177-84. PubMed ID: 17409425
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hypoxia-inducible factors modulate the stemness and malignancy of colon cancer cells by playing opposite roles in canonical Wnt signaling.
    Santoyo-Ramos P; Likhatcheva M; García-Zepeda EA; Castañeda-Patlán MC; Robles-Flores M
    PLoS One; 2014; 9(11):e112580. PubMed ID: 25396735
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors.
    Nilsson MB; Zage PE; Zeng L; Xu L; Cascone T; Wu HK; Saigal B; Zweidler-McKay PA; Heymach JV
    Oncogene; 2010 May; 29(20):2938-49. PubMed ID: 20208561
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The role of hypoxia-inducible factor-1α and -2α in androgen insensitive prostate cancer cells.
    Jeong CW; Yoon CY; Jeong SJ; Hong SK; Byun SS; Kwak C; Lee SE
    Urol Oncol; 2013 Nov; 31(8):1448-56. PubMed ID: 22537539
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multidimensional Screening Platform for Simultaneously Targeting Oncogenic KRAS and Hypoxia-Inducible Factors Pathways in Colorectal Cancer.
    Bousquet MS; Ma JJ; Ratnayake R; Havre PA; Yao J; Dang NH; Paul VJ; Carney TJ; Dang LH; Luesch H
    ACS Chem Biol; 2016 May; 11(5):1322-31. PubMed ID: 26938486
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Opposite functions of HIF-α isoforms in VEGF induction by TGF-β1 under non-hypoxic conditions.
    Chae KS; Kang MJ; Lee JH; Ryu BK; Lee MG; Her NG; Ha TK; Han J; Kim YK; Chi SG
    Oncogene; 2011 Mar; 30(10):1213-28. PubMed ID: 21057546
    [TBL] [Abstract][Full Text] [Related]  

  • 12. c-Myc is regulated by HIF-2α in chronic hypoxia and influences sensitivity to 5-FU in colon cancer.
    Wang L; Xue M; Chung DC
    Oncotarget; 2016 Nov; 7(48):78910-78917. PubMed ID: 27793037
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lenticular cytoprotection. Part 1: the role of hypoxia inducible factors-1α and -2α and vascular endothelial growth factor in lens epithelial cell survival in hypoxia.
    Neelam S; Brooks MM; Cammarata PR
    Mol Vis; 2013; 19():1-15. PubMed ID: 23335846
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential roles of Sirt1 in HIF-1α and HIF-2α mediated hypoxic responses.
    Yoon H; Shin SH; Shin DH; Chun YS; Park JW
    Biochem Biophys Res Commun; 2014 Jan; 444(1):36-43. PubMed ID: 24423936
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BRAF(V600E) efficient transformation and induction of microsatellite instability versus KRAS(G12V) induction of senescence markers in human colon cancer cells.
    Oikonomou E; Makrodouli E; Evagelidou M; Joyce T; Probert L; Pintzas A
    Neoplasia; 2009 Nov; 11(11):1116-31. PubMed ID: 19881948
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Roles of hypoxia-inducible factor-1alpha (HIF-1alpha) versus HIF-2alpha in the survival of hepatocellular tumor spheroids.
    Menrad H; Werno C; Schmid T; Copanaki E; Deller T; Dehne N; Brüne B
    Hepatology; 2010 Jun; 51(6):2183-92. PubMed ID: 20513003
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of 18F-FDG accumulation in colorectal cancer cells with mutated KRAS.
    Iwamoto M; Kawada K; Nakamoto Y; Itatani Y; Inamoto S; Toda K; Kimura H; Sasazuki T; Shirasawa S; Okuyama H; Inoue M; Hasegawa S; Togashi K; Sakai Y
    J Nucl Med; 2014 Dec; 55(12):2038-44. PubMed ID: 25453050
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hypoxia and hypoglycaemia in Ewing's sarcoma and osteosarcoma: regulation and phenotypic effects of Hypoxia-Inducible Factor.
    Knowles HJ; Schaefer KL; Dirksen U; Athanasou NA
    BMC Cancer; 2010 Jul; 10():372. PubMed ID: 20637078
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of 2-methoxyestradiol on apoptosis and HIF-1α and HIF-2α expression in lung cancer cells under normoxia and hypoxia.
    Aquino-Gálvez A; González-Ávila G; Delgado-Tello J; Castillejos-López M; Mendoza-Milla C; Zúñiga J; Checa M; Maldonado-Martínez HA; Trinidad-López A; Cisneros J; Torres-Espíndola LM; Hernández-Jiménez C; Sommer B; Cabello-Gutiérrez C; Gutiérrez-González LH
    Oncol Rep; 2016 Jan; 35(1):577-83. PubMed ID: 26548300
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Concomitant mutations and splice variants in KRAS and BRAF demonstrate complex perturbation of the Ras/Raf signalling pathway in advanced colorectal cancer.
    Seth R; Crook S; Ibrahem S; Fadhil W; Jackson D; Ilyas M
    Gut; 2009 Sep; 58(9):1234-41. PubMed ID: 19474002
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.